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ALCAR (Acetyl L-Carnitine)

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You are buying Acetyl L-Carnitine (ALCAR) is an acetylated form of L-carnitine, derived from the amino acids L-lysine and L-methionine, and is naturally produced in the liver and kidneys. ALCAR and L-Carnitine are used in the human body in the catabolism and transport of fatty acids within mitochondria. Additionally, ALCAR is able to enter the central nervous system, where it acts as a powerful antioxidant. In these ways, ALCAR and L-Carnitine are supportive of energy metabolism and the nervous system.

*NOTE: These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.

Supplement Facts
Alcar Supplement Facts

Disclaimer: This scientific independent research is provided by Aisle7 and is for informational use only. PureBulk provides this information as a service but does not endorse it. Likewise, Aisle7 does not recommend or endorse any specific PureBulk products.



Also indexed as:ALC, L-Acetyl-Carnitine
Acetyl-L-Carnitine: Main Image

Acetyl-L-carnitine is similar in form to the amino acid L-carnitine and also has some similar functions, such as being involved in the metabolism of food into energy. The acetyl group that is part of acetyl-L-carnitine contributes to the production of the neurotransmitter acetylcholine, which is required for mental function.

  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Used for AmountWhy
Age-Related Cognitive Decline
1,500 mg daily3 stars[3 stars]
Several clinical trials suggest that this supplement delays onset of ARCD and improves overall cognitive function in the elderly
500 to 1,000 mg three times daily 3 stars[3 stars]
Taking acetyl-L-carnitine may improve symptoms of diabetic neuropathy.
Alzheimer’s Disease
1 gram taken three times per day2 stars[2 stars]
Short-term studies have found that people with Alzheimer’s disease who supplement with acetyl-L-carnitine experience improved memory, enhanced overall performance, and delayed disease progression.
Refer to label instructions 2 stars[2 stars]
Acetyl-L-carnitine has been shown in several studies to significantly reduce depression symptoms in seniors.
Down’s Syndrome
500 mg three times per day2 stars[2 stars]
Acetyl-L-carnitine appears to improve visual memory and attention in people with Down’s Syndrome.
Erectile Dysfunction

2 grams of each daily2 stars[2 stars]
In one study, supplementing with the combination of propionyl-L-carnitine (a form of L-carnitine) and acetyl-L-carnitine significantly improved erectile function in elderly men.
1,500 mg daily for ten weeks 2 stars[2 stars]
Supplementing with acetyl-L-carnitine may improve musculoskeletal pain, depression, and general health in people with fibromyalgia.
Liver Cirrhosis
2 grams twice a day for 3 months 2 stars[2 stars]
A double-blind trial suggests that supplementing with acety-l-carnitine may improve mental and neurological function in people whose cirrhosis has impaired function.
Macular Degeneration

(Coenzyme Q10, Fish Oil)
Follow label directions2 stars[2 stars]
In one study, supplementing with a proprietary blend of acetyl-L-carnitine, fish oil, and coenzyme Q10 improved visual function in people with macular degeneration.
Type 1 Diabetes and Diabetic Neuropathy
500 to 1,000 mg three times per day2 stars[2 stars]
Taking acetyl-L-carnitine may improve symptoms of diabetic neuropathy.
Type 2 Diabetes and Diabetic Neuropathy
500 to 1,000 mg three times daily2 stars[2 stars]
Taking acetyl-L-carnitine may improve symptoms of diabetic neuropathy.
Refer to label instructions 1 star[1 star]
Acetyl-L-carnitine may help restore menstruation in some amenorrheic women.
Male Infertility
Refer to label instructions 1 star[1 star]
Acetylcarnitine may be a useful for treatment of male infertility caused by low quantities of immobile sperm.

Copyright © 2014 Aisle7. All rights reserved.

Learn more about Aisle7, the company.

Learn more about the authors of Aisle7 products.

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

Additional Information

Is Acetyl L-Carnitine (ALCAR) water soluble?
This product dissolves quickly in water and has a moderately sour but pleasing taste that mixes well with citrus drinks like lemonade. Mix the product with a citrus juice or dissolve in water and drink.

The bioavailability of Acetyl-L-Carnitine (ALCAR) is significantly greater than other carnitine supplements

What is the difference between Acetyl L-Carnitine (ALCAR) and L-Carnitine? Is one more effective than the other, or can a person take both?
The difference between Acetyl L-Carnitine and L-Carnitine Base is the attached acetyl group in the Acetyl L-Carnitine versus the free-form amino acid L-Carnitine Base, which does not include this added molecule.

The Acetyl L-Carnitine is considered to have increased bioavailability for crossing neurological membranes and therefore is taken for nootropic and neurological health benefits. The L-Carnitine Base, on the other hand, is generally taken for cardiovascular health and as a fat burner.

ALCAR is generally not recommended as a fat burner and for weight loss because it is too bioactive neurologically. Taking the higher serving sizes necessary to be effective as a fat burner is considered too large an amount given it’s neurological effects.

Both have differing targeted uses although there is overlap, and some recommend taking both

Customer Reviews
Review by Greg on 11/26/2012
Hard to capsulate. This stuff sticks to itself, and isn't very "powdery" or "grainy" - so it's hard to put into pills :| Wish I got it pre-capsuled.
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Size Conversion
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  • 0.88 oz
  • 1.76 oz
  • 3.5oz
  • 8.8oz
  • 1.1lb
  • 1.65lb
  • 2.2lb
  • 3.3lb
  • 11lb