Conjugated Linoleic Acid Oil 80%
| Name/Weight | Volume | Price | |
|---|---|---|---|
Conjugated Linoleic Acid Oil 80% 250ml |
1200cc | $19.25 | |
Conjugated Linoleic Acid Oil 80% 500ml |
2000cc | $34.75 | |
Conjugated Linoleic Acid Oil 80% 1000ml |
2800cc | $62.50 |
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What is Conjugated Linoleic Acid Oil?
Conjugated Linoleic Acid (CLA), a slightly altered form of the essential fatty acid linoleic acid, is an omega-6 essential fatty acid (EFA) found in corn oil, safflower oil, sunflower oil, canola oil, nuts, seeds, beef and dairy products, which is said to burn fat, build muscle, and fight cancer. This naturally occurring free fatty acid found mainly in meat and dairy products was discovered by accident in 1978 by Michael W. Pariza at the University of Wisconsin while studying beef extract for cancer prevention and while looking at mutagen formations in meat during cooking. What he discovered instead lead him to look further and research into the benefits of CLA as a fat reducer. After looking at decades of research scientists have found that CLA may in fact help the body to deposit less fat, build more muscle and may even help prevent fat cells from refilling. CLA is research proven to build muscle, reduce body fat, and induce an optimum cellular environment for improved health. CLA has been called “the good fat” and “the fat that makes you thin,” but the average American diet provides less than 1 gram of conjugated linoleic acid a day. Some researchers point to the consumption of less and less CLA as one of the reasons for the rise of obesity in America point.Conjugated Linoleic Acid Oil is a trans-fatty acid, but because it is also a conjugated system, it is believed by many researchers to be beneficial for human consumption. The FDA does not consider CLA to be a trans fat for the purposes of nutritional regulations or product labeling. Unlike other trans-fatty acids in the human diet CLA occurs naturally. In human nutritional research studies have shown that dietary supplementation of CLA may markedly reduce body fat, and in particular abdominal fat, and significantly increase muscle mass. Conjugated linoleic acid (CLA) is not a single substance because it is a mixture of positional and geometric isomers of linoleic acid (cis-9, cis-12-octadecadienoic acid). Conjugated linoleic acid is a naturally occurring mixture of various isomers of linoleic acid with conjugated double bonds. In contrast to linoleic acid, all the CLA isomers have conjugated bonds. Conjugated linoleic acid is a diunsaturated long chain (C18) fatty acid. CLA comprises a group of positional and geometric isomers of linoleic acid in various configurations of cis.
Linoleic acid is known as an "essential" fatty acid, meaning that a person must obtain it from external dietary sources since it the body does not make it. Conjugated linoleic acid (CLA) has become the focus of numerous research programs which seek to capitalize on its nutritional, therapeutic, and pharmacologic properties. The isomers of CLA have different shapes, functions, and benefits. CLA supplements, or fats containing CLA, generally contain a mixture of these isomers. Many studies on CLA in humans include the tendency for reduced body fat, particularly abdominal fat, changes in serum total lipids, and decreased whole body glucose uptake. Dietary CLA supplementation appears to be safe as it does not have any adverse effects. The maximum response to lower body fat mass was attained with a 3.4 g daily dose. CLA possesses anticarcinogenic properties. In addition to the mammary gland, CLA has also been demonstrated to play a role in helping regulate lipid and energy metabolism in other tissues.
What is Conjugated Linoleic Acid Oil used for and who uses it?
Also known as CLA, this supplemental fatty acid has been extensively studied in animal subjects, where it shows promise as a way to reduce cholesterol, combat cancer, and even minimize body fat. In laboratory studies, CLA uses its antioxidant properties to slow and retard the growth of cancerous cells in the skin, breast, colon, and lung. To the athlete who wants to gain pounds in the form of muscle while dropping body fat, CLA is an effective compound that will be extremely helpful in getting anyone reach that goal easier and faster, while getting the positive impact on immune function and antioxidant status in the process as well.CLA works within your body in 4 possible different ways. First, CLA naturally suppresses an enzyme in the body called lipoprotein lipase or LPL, thus decreasing LPL activity which results in your body depositing and storing less fat altogether. Second, CLA effectively reduces the size and the number of fat cells in your body, otherwise known as adipocytes. Third, CLA hastens and facilitates the natural process of fat cell disintegration, otherwise known as “cell suicide” or the more clinical term, “apoptosis.” CLA enhances your body’s apoptosis rate (rate at which fat cells disintegrate) thus reducing the number of fat cells that will be stored in your body. Lastly, a CLA supplement can improve the activity of another enzyme called carnitine palmitoyltransferase or CPT, (which is responsible in transporting fatty acids converted to energy you need to keep going), thus burning fat at a much faster rate.
Research confirms CLA or conjugated linoleic acid may indeed be effective in reducing and eliminating significant amounts of body fat. In clinical studies done with mice, CLA lowered body fat by 88 percent in as short as six weeks. In humans preliminary studies on the benefits of CLA have been promising as well. In the December 2000 issue of the Journal of Nutrition, participants in a double-blind study who ingested CLA dropped six pounds more body fat relative to those in the placebo group. Overall data for this study concluded that 3.4 grams of CLA daily is necessary to significantly reduce body fat.
Conjugated linoleic acid has been looked at as a possible treatment for numerous diseases, including breast cancer, obesity, as well as myocardial infarction or heart disease. It may also help trigger improved metabolism, build muscle, strengthen the immune system, and help manage and keep optimal and healthy blood sugar levels. In a study done at Purdue University in Indiana, CLA was shown to significantly improve insulin levels in almost 70 percent of diabetic patients, and moderately lowered the blood glucose level and triglyceride levels. CLA supplementation may be particularly beneficial to those with diabetes or hypothyroidism, although anyone with a serious illness should first check with a doctor before considering new supplements.
How pure is your Conjugated Linoleic Acid Oil?
Conjugated Linoleic Acid Oil 80% is assayed by the manufacturer to be 81.06% total CLA content. You will receive a sealed and labeled heavy duty 4 mil polyethylene bag containing this clear to slightly yellow liquid oil. The total CLA composition of this pure bulk liquid oil product is 81.06% by weight with the remaining non-CLA products being other food grade vegetable oils as assayed in the attached COA (Certificate of Analysis).CLA occurs naturally in foods such as milk, cheese, beef, and lamb as well as many processed foods. One processed food in particular that's high in CLA is Cheez Wiz. But getting enough CLA from your diet for the preferred benefit would require considerable intake of these types of foods. Ironically, high-fat meats, such as ground beef and lamb, and full-fat dairy products, foods generally viewed as dietary bad guys, are the richest natural dietary sources of CLA. This is not only impractical, but would also have a seriously negative impact on your metabolism due to the high caloric penalty you would pay. Also, since the body doesn't make it, CLA can only come from the foods you eat. As such, the only way to get sufficient CLA is through supplementation. Due to the fact that our product is pharmaceutical grade, these are best utilized by the body, since they do not require digestion and are easily absorbed. Our product also has no additives, fillers or extenders included. For individuals who want the most Conjugated Linoleic Acid (CLA) for their money, this pure bulk product is one of the most potent and economical CLA supplement available. Buying in bulk is also your best bet for saving money because for sure you’ll pay more at a local nutrition store. Bulk costs are cheaper in the long run and you will receive a great deal at or below wholesale prices for a high purity bulk quantity of this product.
Do the Math! Why pay for expensive CLA capsules costing 3 to 4 times as much as this pure bulk wholesale 80% CLA oil? Typically a 90 capsule bottle of CLA will require 2 capsules at 500 milligrams each to yield 1 gram CLA, and each 90 capsule bottle (containing 45 grams CLA) will cost $20 or more! At that price per gram this 80% CLA oil might sell for hundreds of US dollars or more! This pure bulk wholesale 80% CLA oil is the most economical way to burn off that abdominal fat and look great!
What is the daily suggested dose of Conjugated Linoleic Acid Oil?
The recommended daily dose for CLA varies between 3 and 5 grams divided between two or three doses per day with meals. You can see the full bulk density/volumetric conversion chart for Conjugated Linoleic Acid Oil here. After considering that the CLA content of this product is 80% of the total oil, proper dosing will require you to measure by volume (or weight) approximately 25% more of this bulk oil product so as to net your desired CLA dose. For example, suppose you wanted to consume a daily dose of 4 grams CLA divided in two doses, one with your breakfast meal and the other with your evening dinner. You would therefore want to consume 2 grams CLA per dose. But since it takes 1.25 times as many grams of this bulk oil you would need to take 2.5 grams of this bulk oil twice per day to net 2 grams twice per day (totaling a net of 4 grams per day) CLA. Your daily dose of this CLA 80% oil, therefore, would be 5 grams divided in two 2.5 gram doses in this example. You may elect to take more or less than 5 grams per day of this bulk oil to meet your individual needs. Since this is an oil it does not dissolve at all in water and it has a characteristic taste and feel in the mouth that is probably unlike any oil with which you are familiar.Potential side effects of Conjugated Linoleic Acid Oil
CLA is available in most drugstores and health food stores in capsules or softgels, and often marketed as a weight-loss formulas or fat burners with potencies between 600mg and 1000mg. There have been no toxic effects linked to CLA supplementation, although some people do report stomach upset when they take extremely high doses. All preliminary evidence shows that CLA is nontoxic and safe at recommended dosages.Taste, solubility, and suggested preparation of Conjugated Linoleic Acid Oil
This pure bulk CLA oil isn’t repulsive, but it may come as a surprise for people who are not too used to it as it does not taste very good either, and it tends to leave a somewhat unpleasant aftertaste and as well as an unpleasant film or coating in your mouth and on your teeth (which usually disappears after a few minutes). If you are taking 2.5 grams of this bulk oil to yield 2 grams CLA per dose, you will want to measure out approximately one level 1/2 teaspoon (netting about 2.2 grams bulk oil). Mix 1/2 slightly rounded teaspoon in a glass with about 4 ounces hot water and stir and drink. Or, for increased bioavailability you can mix CLA with 8 ounces hot whole milk, half and half, or coconut milk. The fat content of the milk and/or coconut milk will help to dissolve the CLA and allow it to be digested and absorbed more efficiently. But before you do this, consider that CLA does taste somewhat bad and to overcome CLA's bad taste you might consider adding masking flavors such as hot sauce or sugar and then pinching your nose while drinking. You may want to have a glass of clear and flavorful beverage handy to chase down the CLA after drinking (wine can work fairly well as a chaser for most people).Conjugated Linoleic Acid Oil is used in the following Proprietary Formulas
Tonalin, MRM CLA 1250, Nutrex Lipo 6x, PrimaForce Max CLA, Universal Animal Omega, Optimum CLA, AllMax Nutrition CLA 80 Femme, AST CLA 1000, Cheap Supplements CLA, Country Life CLA Tonalin, Dymatize CLA, EAS CLA, HDT CLA 1000, Higher Power CLA, Iron-Tek Essential CLA, LiveLong Nutrition CLA-1000, Magnum Nutraceuticals Acid, Met-Rx Tonalin CLA, Myogenix CLA, Natrol Tonalin CLA, NOW CLA, Olympian Labs CLA, PhytoCeutical OptiCLA, PrimaForce Max CLA, Prolab CLA, SciFit Conjugated Linoleic Acid, Twinlab CLA FuelReferences & Further Research
Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitusSome animal studies have suggested that conjugated linoleic acid CLA supplementation may have therapeutic potential with respect to insulin sensitivity and lipid metabolism, which are important cardiovascular disease (CVD) risk factors associated with type 2 diabetes mellitus. We investigated the effect of CLA supplementation on markers of glucose and insulin metabolism, lipoprotein metabolism, and inflammatory markers of CVD in subjects with type 2 diabetes. The study was a randomized, double-blind, placebo-controlled trial. CLA supplementation significantly increased fasting glucose concentrations and reduced insulin sensitivity. The ratio of LDL to HDL cholesterol was significantly reduced. CLA supplementation reduced fibrinogen concentrations but had no effect on the inflammatory markers of CVD (C-reactive protein and interleukin 6). CLA supplementation had an adverse effect on insulin and glucose metabolism. Whereas CLA had positive effects on HDL metabolism and fibrinogen, a therapeutic nutrient should not be associated with potentially adverse effects on other clinical markers of type 2 diabetes.
Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans
Background: Short-term trials showed that conjugated linoleic acid CLA may reduce body fat mass (BFM) and increase lean body mass (LBM), but the long-term effect of CLA was not examined. Objective: The objective of the study was to ascertain the 1-y effect of CLA on body composition and safety in healthy overweight adults consuming an ad libitum diet using a double-blind, placebo-controlled study. Subjects were randomly assigned to 3 groups: CLA free fatty acid (FFA), CLA triacylglycerol, or placebo (olive oil). Overall data indicate long-term supplementation with CLA FFA or CLA triacylglycerol reduces body fat mass (BFM) in healthy overweight adults.
Conjugated linoleic acid inhibits proliferation and modulates protein kinase C isoforms in human prostate cancer cells
Prostate cancer is the second most common cancer in men. The disease etiology is poorly understood, but diet and lifestyle are contributory factors. Conjugated linoleic acids CLA, naturally occurring fatty acids in ruminant food products, have antitumor properties in animal models of cancer and antiproliferative effects on cancer cells in vitro. The cellular mechanisms by which CLA elicit these effects are unclear, particularly for prostate cancer cells. We have previously identified protein kinase C (PKC) isoforms, alpha, delta, iota, mu, and zeta in LNCaP prostate cancer cells. The objective of this study was to determine the effects of CLA (individual cis-9, trans-11 and trans-10, cis-12 isoforms and a 50:50 mixture) on PKC isoform abundance in LNCaP cells. CLA clearly modulated the abundance of these PKC isoforms, both positively and negatively, depending on the isoform, concentration of CLA, and period of treatment. Increased PKC-delta and decreased PKC-iota membrane abundance was consistent with CLA eliciting increased apoptosis and, in part, with their antitumor effects.
The effect of conjugated linoleic acid CLA supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects
To study the effects of 13 weeks conjugated linoleic acid CLA supplementation in overweight subjects after weight loss on weight regain, body composition, resting metabolic rate, substrate oxidation, and blood plasma parameters. Subjects either received 1.8 g CLA or placebo per day (low dosage, LD) or 3.6 g CLA or placebo per day (high dosage, HD). Multiple regression analysis showed that at the end of the 13-week intervention, CLA did not affect % body weight regain. In conclusion, the regain of fat-free mass was favorably, dose-independently affected by a 13-week consumption of 1.8 or 3.6 g CLA per day and consequently increased the resting metabolic rate. However, it did not result in improved body weight maintenance after weight loss.
Conjugated linoleic acid supplementation in humans--metabolic effects
Supplementation with conjugated linoleic acid CLA induces a number of physiological effects in experimental animals, including reduced body fat content, decreased aortic lipid deposition, and improved serum lipid profile. Controlled trials on the effects of CLA in humans have hitherto been scarce. The aim of this study was to evaluate the effects of supplementation with CLA in healthy humans on anthropometric and metabolic variables and on the fatty acid composition of serum lipids and thrombocytes. Results suggest that supplementation with CLA may reduce the proportion of body fat in humans and that CLA affects fatty acid metabolism.