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What is Creatine Ethyl Ester Malate - CEEM?

The best creatine supplement used by bodybuilders may be a matter of taste, with Creatine Ethyl Ester Malate (CEEM) considered one of the most effective forms of the product.

Creatine Ethyl Ester Malate is very similar to creatine ethyl ester HCL, but it tastes better and has fewer side effects in large doses.

Compared to creatine monohydrate, CEEM does not require a loading phase, making it less expensive to use.

Athletes working to increase stamina and sports performance find creatine benefits to be a useful tool. A review of clinical studies has found a preponderance of scientific evidence indicating creatine supplementation may be effective for a variety of exercise tasks.

The ethyl ester link in this creatine product increases absorption of the product. There is less waste and fewer gastrointestinal problems because of the small serving sizes needed.

Creatine is manufactured in the liver by methylation of guanidoacetate using S-adenosyl methionine (SAM) as the methyl donor. Creatine may also be derived from dietary sources, primarily from meat or fish, which contain approximately 4 to 5 grams of creatine per kilogram. Following its biosynthesis, creatine is quickly taken to the skeletal muscle, heart, brain and other tissues. Most of the creatine is metabolized in these tissues into phosphocreatine (creatine phosphate), which is a primary energy storage form in the body.

Creatine increases the availability of cellular energy ATP, adenosine triphosphate, by donating a phosphate ion. When energy demand is high, creatine phosphate helps ADP (adenosine diphosphate) produce ATP, which drives muscle contraction and protein production. This reaction is reversible. The phosphate of ATP can be transferred back to creatine, generating creatine phosphate by the action of creatine phosphokinase. Phosphocreatine is then stored in the muscle for later energy use. When needed, phosphocreatine later binds with ADP to convert it back to ATP.

Creatine has grown quite popular in recent years. Studies indicate it may support muscle gain. Creatine's influence on ATP is crucial for metabolic activities, especially high performance sports such as weightlifting, sprinting and jumping.

PureBulk also sells creatine gluconate and dicreatine malate.

Health Benefits of Creatine Ethyl Ester Malate

Studies have shown that creatine ethyl ester malate, when supplemented with proper diet, exercise and adequate hydration, may aid muscle development. Creatine also helps with faster recovery times, allowing for increased training sessions.

Adding muscle mass leads to weight gain, a result of creatine drawing water into the muscle cell.

Purity and Concentration of Creatine Ethyl Ester Malate

This pharmaceutical grade creatine ethyl ester malate (CEEM) contains no fillers, additives or anti-caking agents.

Potential Side Effects of Creatine Ethyl Ester Malate

CEEM is generally recognized as safe and there are no known side affects found in the many studies performed on CEEM powder. Renal dialysis or kidney transplant patients may have trouble eliminating CEEM.

Suggested Use of Creatine Ethyl Ester Malate

The suggested serving size for CEEM is 3000 milligrams (a scant 1/2 tablespoon) taken with water 30 to 60 minutes before a workout, depending on individual needs or as directed by a physician. May repeat after a workout. You can see the full bulk density/volumetric conversion chart for creatine ethyl ester malate here.

Bioavailability, Mixing, and Solubility of Creatine Ethyl Ester Malate

CEEM is an odorless white-colored crystalline powder, which appears colorless and clear in solution. CEEM absorbs quickly. Mix with citrus juice or beverage. Do not use caffeine while on creatine. Caffeine is a diuretic. Creatine makes muscles hold water, caffeine does the opposite. For best results, CEEM can be consumed one hour before and/or after training with a high glucose drink for better CEEM transport.

Do not mix CEEM powder too far in advance. It will eventually separate from the liquid and break down. Mix only the amount needed. For those on the go, simply measure the correct amount of powder into an empty beverage container. When ready fill the bottle with the preferred drink.

Drink lots of water while on creatine. To perform its work in cell volumization of the muscle and to make the muscle larger and firmer, creatine needs water. Drink at least a full 8-ounce glass of water eight times a day.

References & Further Research

WebMD: An Overview of Creatine Supplements

University of Maryland Medical Center: Creatine

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.