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What is Creatine Gluconate?

Creatine Gluconate is a molecule of creatine bonded to a molecule of glucose [or gluconic acid]. It is the most easily absorbed creatine ever created. From the name itself, this product is simply creatine bonded to sugar or glucose. It maintains all the properties and gives the same benefits found in any other type of creatine, only with a much better absorption rate as its main edge over its counterparts. Since sugar helps the uptake of creatine in the cell, the result is creatine that gets absorbed into the system easily and almost completely. Owing to creatine gluconate being bonded to a fast-digesting carb which is glucose, the amount of creatine uptaken into the muscles is significantly increased.

Creatine is manufactured in the liver by methylation of guanidoacetate using SAM as the methyl donor. Guanidoacetate itself is synthesized in the kidney from the amino acids arginine and glycine. Creatine may also be derived from dietary sources primarily from eating meat or fish, which contains approximately four to five grams of creatine per kilogram. Following its biosynthesis, creatine is quickly taken to the skeletal muscle, heart, brain and other tissues. Most of the creatine is metabolized in these tissues to phosphocreatine (creatine phosphate), which is a primary energy storage form in the body. Creatine functions to increase the availability of cellular ATP, adenosine triphosphate. Creatine works by acting on mechanisms of ATP by donating a phosphate ion to increase the availability of ATP. Creatine is primarily stored in the muscle as free creatine and phosphocreatine. Creatine is used as a storage form of high energy phosphate. The phosphate of ATP is transferred to creatine, generating creatine phosphate, through the action of creatine phosphokinase. The reaction is reversible such that when energy demand is high (e.g. during muscle exertion) creatine phosphate donates its phosphate to ADP to yield ATP. hosphocreatine binds with adenosine diphosphate to convert it back to ATP (adenosine triphosphate), an important cellular energy source.

When Creatine Gluconate is absorbed, it is broken down into creatine and sugar. This in turn catalyzes insulin secretion which drives the creatine and other nutrients directly into your muscles. Using glucose as a delivery system, Creatine Gluconate represents a very safe and efficient form of cutting edge creatine. Creatine Gluconate, has not been reported to cause gastro intestinal bloating, intestinal discomfort, nausea or frequent urination problems unlike the other creatine analogs. The reason why these side effects are so common with many other creatine varieties is because other creatine analogs can be poorly absorbed through the intestines in some individuals. Poor creatine absorption and the discomforts of intestinal bloating, nausea and frequent urination problems do not affect all users of other creatine supplements but these side effects can be problematic for many individuals. With Creatine Gluconate, reports of intestinal bloating and other gastrointestinal related problems are rare and very seldom reported because it is so quickly and efficiently absorbed through the intestines and into portal circulation.

Creatine supplementation has become tremendously popular in recent years. Creatine has been clinically proven in numerous studies to increase muscle strength, and to delay fatigue, allowing athletes to train harder and achieve greater muscle gains beyond normal capacities. During high-intensity, short-duration exercise, such as lifting weights or sprinting, phosphocreatine is broken down into creatine and phosphate. The energy released in this process is used to regenerate ATP, a major source of energy within the human body that drives a number of biological processes including muscle contraction and protein production. ATP is used for all metabolic activities and is crucial for anaerobic activity such as weightlifting, sprinting and jumping that are short-term, high intensity activities the utilize fuel rapidly.

What is Creatine Gluconate used for and who uses it?

Creatine Gluconate essentially works just like other creatine sports supplements as an aid in increasing muscle mass significantly, improving high-energy sports performance, increasing energy levels and speeding up recovery. The main difference is with creatine gluconate, there is better absorption, which translates to improved gains and faster results. The reputed benefit of combining creatine and glucose into a single molecule is twofold. First, the Creatine Gluconate is absorbed faster or more completely through the gut and into systemic blood circulation than Creatine Monohydrate and other creatine analogs. Second, the absorption of Creatine Gluconate into muscle cells occurs more quickly and continuously thereby increasing muscle mass more effectively. Creatine Gluconate does not require a loading phase compared to other creatine products, and results can usually be noticed with as little as 3 days supplementation and physical training. They are primarily used by athletes who wish to build up their muscles and increase energy levels fast, including powerlifters, weightlifters, bodybuilders, sprinters, rowers and runners. This can also be used by people who go to the gym to increase muscle mass faster and to boost overall energy levels.

How pure is your Creatine Gluconate?

This Creatine Gluconate is a pure bulk nutritional powder assayed by the manufacturer to be 99.65% pure. This is an ultra white nutritional raw material powder with no additives, fillers or anticaking agents included. The remaining 0.35% by weight are inactive byproducts of the extraction. Creatine supplements fuels and enhances short bursts of high-energy exercise, increases both total work output in a single high intensity exercise bout, and increases the peak performance during a series of repetitive bouts. Low levels of creatinine are not common and are not usually a cause for concern. However, people involved in intense physical activity, especially those limiting their intake of red meat, may have low muscle stores of creatine. Creatine deficiency in situations of strenuous muscle function results in fatigue, lessened muscle strength, compromised endurance, increased muscle soreness, and the need for frequent resting. For these reasons, supplementation may be necesssary.

Precautions and Potential side effects of Creatine Gluconate

There has been no documented adverse creatine side effect primarily because it is a natural by-product of the body’s metabolism to begin with. Extensive experiments have been done to test the side effects of creatine on humans, and to date, the only documented adverse effect of creatine supplementation is an increase in body mass, which is in almost all cases something all bodybuilders, powerlifters, and strength athletes can live with. Be advised though that long term studies on high dosage effects on creatine use have not been done yet. It’s always recommended to just stick with the instructions on the label so as to not over do it.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

What is the solubility, taste, and recommended daily dose of Creatine Gluconate?

Creatine Gluconate dissolves or mixes readily in water. Thousands of athletes from around the world involved in various sports from the high school ranks to the professional level can attest to their great results using 5 to 10 grams of creatine per day. Creatine Gluconate has a mildly sour flavor and tastes reasonably good after mixing with water, fruit juice, or blended in your protein or energy shake. Creatine Gluconate really does have a very good taste as compared any other creatine analog supplement. Aside from shakes and beverages, people who take creatine with their daily meals like oats for example have also reported excellent results from such an approach.

The commonly recommended dose for Creatine Gluconate varies from as little as 1 gram (1,000 milligrams) once or twice per day to as much as much as 5 grams (5,000 milligrams) once or twice per day, depending upon individual needs. One half level teaspoon of this pure bulk powder Creatine Gluconate will weigh approximately 1.9 grams (1896 milligrams). You can see the full bulk density/volumetric conversion chart for Creatine Gluconate here. Take 4 grams of this Creatine Gluconate powder mixed with water or juice just previous to your workouts, and then take another 4 grams just before bed. Your total daily dose will be 8 grams on workout days or 4 grams on non-workout days. You may increase your dose for more optimal results and increased muscle mass gains if desired. If you experience any side effects from increased dosing or you find little or no improvement from your previous dose after 7 days cut back to find your optimal, or maximally effective daily dose.

It is recommended to drink lots of water while on the creatine, no matter what type of creatine you select. To perform its work in cell volumization of the muscle, and to make the muscle larger and firmer, creatine needs water, so it’s important to be well-hydrated or to replenish your water as needed. At the very least, drink a full eight ounce glass of water 8 times a day. Creatine Gluconate can be taken with most beverages and even with oats, but keep in mind to not use caffeine while on creatine. This is because caffeine reduces the effects of the creatine intake due to its nature of being a diuretic. While creatine makes your muscles hold water, caffeine will do the opposite, thereby neutralizing the benefits of creatine intake.

As always, if you have concerns or questions, consult a physician or a health care professional before taking any supplements. Before taking any kind of medicine, check with your doctor to ensure that the supplement you want to take is right for you. You may be allergic or you may have a sensitive stomach which may raise the need for special instruction as far as dosage goes.

What kind of results do people anticipate while taking Creatine Gluconate?

During workouts and trainings, you'll feel stronger, more powerful, and you’ll be much more energized to train longer and harder. A side effect of creatine is water retention, and this translates to fuller and bigger muscles and gains in muscle mass. You'll also be able to lift slightly heavier weights and feel less fatigue.

Creatine Gluconate is used in the following Proprietary Formulas

DNAccelerator by Next Generation Labs, SizeOn Tabs/Powder by Gaspari Nutrition, Creatine Gluconate by NutraPlanet, CREATure by Beast Sports Nutrition, Nutrex VoluGro, Maximize by I Force, Ultimate Mass Pump Stack

References & Further Research

Oral creatine supplementation enhances upper extremity work capacity in persons with cervical-level spinal cord injury
The objective of this study is to examine the effects of short-term creatine monohydrate supplementation on the upper extremity work capacity of persons with cervical-level spinal cord injury (SCI) using a randomized, double-blind, placebo-controlled, crossover design study. Overall data suggest Creatine supplementation enhances the exercise capacity in persons with complete cervical-level SCI and may promote greater exercise training benefits.

Creatine supplementation in young soccer players
The purpose of this study was to examine the effects of acute creatine-monohydrate supplementation on soccer-specific performance in young soccer players. Twenty young male soccer players participated in the study and were matched and allocated to 2 randomly assigned trials: ingesting creatine-monohydrate supplement (3 x 10-g doses) or placebo for 7 days. Before and after the supplementation protocol, each subject underwent a series of soccer-specific skill tests: dribble test, sprint-power test, endurance test, and vertical jump test. Specific dribble test times improved significantly in the creatine group after supplementation protocol. Sprint-power test times were significantly improved after creatine-monohydrate supplementation as well as vertical jump height in creatine trial. Furthermore, dribble and power test times, along with vertical jump height, were superior in creatine versus placebo trial at post-supplementation performance. The main finding of the present study indicates that supplementation with creatine in young soccer players improved soccer-specific skill performance compared with ingestion of placebo.

Is the use of oral creatine supplementation safe?
This review focuses on the potential side effects caused by oral creatine supplementation on gastrointestinal, cardiovascular, musculoskeletal, renal and liver functions. No strong evidence linking creatine supplementation to deterioration of these functions has been found. In fact, most reports on side effects, such as muscle cramping, gastrointestinal symptoms, changes in renal and hepatic laboratory values, remain anecdotal because the case studies do not represent well-controlled trials, so no causal relationship between creatine supplementation and these side-effects has yet been established. The only documented side effect is an increase in body mass. Recently, controlled studies made to integrate the existing knowledge based on anecdotal reports on the side effects of creatine have indicated that, in healthy subjects, oral supplementation with creatine, even with long-term dosage, may be considered an effective and safe ergogenic aid. However, athletes should be educated as to proper dosing or to take creatine under medical supervision.

Creatine supplementation during pulmonary rehabilitation in chronic obstructive pulmonary disease
Skeletal muscle wasting and dysfunction are strong independent predictors of mortality in patients with chronic obstructive pulmonary disease (COPD). Creatine nutritional supplementation produces increased muscle mass and exercise performance in health. A controlled study was performed to look for similar effects in 38 patients with COPD. Creatine increased fat-free mass by 1.09 kg post loading and 1.62 kg post rehabilitation. Peripheral muscle performance improved: knee extensor strength 4.2 N.m and endurance 411.1 J post loading. Creatine supplementation led to increases in fat-free mass, peripheral muscle strength and endurance, health status, but not exercise capacity. Creatine may constitute a new ergogenic treatment in COPD.

Creatine supplementation and cognitive performance in elderly individuals
The purpose of this study was to examine the effect of creatine supplementation on the cognitive performance of elderly people. Participants were divided into two groups, which were tested on random number generation, forward and backward number and spatial recall, and long-term memory tasks to establish a baseline level. Results showed a significant effect of creatine supplementation on all tasks except backward number recall. It was concluded that creatine supplementation aids cognition in the elderly.

Creatine Gluconate for International Customers

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