PureBulk

Note: This product is NOT Vegan. However, we do offer a vegan alternative if you prefer.

Related Purebulk products:

D-glucosamine-sulfate-potassium powder, d-glucosamine-sulfate-k gelatin and vegetarian capsules.

What is D-Glucosamine Hydrochloride Powder (Shellfish)?

Glucosamine, an amino derivative of the simple sugar glucose, supports cartilage and is an important constituent of many natural polysaccharides.

This D-glucosamine hydrochloride powder is obtained from the shells of crustaceans. It is made up of a sugar molecule (glucose), an amino group and a hydrochloride group. It contains 98% glucosamine, the most abundant naturally occurring amino sugar.

Glucosamine is made from glucose and the amino acid glutamine. Glucosamine helps the body synthesize and produce specialized molecules called glycosaminoglycans(Wikipedia). Glucosamine plays an important role as an intermediate in the biosynthetic pathway of proteoglycans, the main building blocks of connective tissue and cartilage.

Glucosamine is available in different forms, including glucosamine hydrochloride, glucosamine hydroiodide, glucosamine sulphate and N-acetyl glucosamine.

Glucosamine is often taken with chondroitin. Glucosamine and chondroitin sulfate are both basic constituents of articular cartilage. These substances are often taken together with manganese as well, a trace metal that is also needed for building cartilage.

Glucosamine, manufactured in a laboratory from chitin, a substance found in the shells of shrimp, crab, lobster, and other sea creatures, is often used as ingredient in sports drinks and cosmetics.

Glucosamine is sometimes combined with methylsulfonylmethane in nutritional supplements.

Difference between the other Glucosamine salts

There have been discussions over which of the two glucosamine salts, hydrochloride or sulfate, is preferred. Both salts, in the pure form, deliver equally effective amounts of glucosamine to joint cartilage. If there is a preference, it is usually based on relative purity and economics. Purebulk also offers D-glucosamine Sulfate Potassium in powder or capsules.

Benefits of D-Glucosamine-HCL

Glucosamine replenishes synovial fluids. It is easily absorbed into the bloodstream and is important in the formation and development of skin, eyes, bones, tendons, nails, ligaments and parts of the heart.

Glucosamine supplies the primary substrate for both collagen and proteoglycan synthesis. Glucosamine triggers the synthesis and production of glycosaminoglycans and proteoglycans, two crucial building blocks of cartilage. The polysaccharide groups in proteoglycans are known as glycosaminoglycans or GAGs. GAGs include hyaluronic acid, chondroitin sulfate, dermatan sulfate, keratan sulfate, heparin and heparan sulfate. All of the GAGs contain abundant derivatives of glucosamine or galactosamine. Glucosamine also triggers the integration of sulfur into cartilage, which is necessary for making and repairing cartilage.

Glucosamine has chondroprotective properties which appears to aid in balancing synthesis and degradation of cartilage tissue.

Glucosamine is needed in the production of mucus as a protective coating in the urinary, digestive and respiratory tracts, and it is also important for healthy skin. Sufficient levels of glucosamine in the blood are necessary for the production of hyaluronic acid, one of the substances needed to heal skin injuries.

Purity and Concentration of D-Glucosamine-HCL

This food grade D-glucosamine HCL nutritional supplement contains no fillers, taste additives or anti-caking agents.

D-Glucosamine HCL is cost-effective and provides a pure and stable source of glucosamine readily absorbed by the body.

Potential Side Effects of D-Glucosamine-HCl

Glucosamine sulfate can cause mild side effects including nausea, heartburn, diarrhea, and constipation. Uncommon side effects include drowsiness, skin reactions and headache.

Pregnant women and breast-feeding mothers should not take glucosamine. Persons with allergies to shellfish should not take this product as it is derived from shrimp and crab shells. Persons with diabetes should consult their physician before use. People with asthma should be cautious about taking products containing glucosamine.

Recommended Use of D-Glucosamine HCL

The recommended serving size for D-glucosamine HCL is 1000 milligrams taken up to three times daily, depending on individual needs. You can see the full bulk density/volumetric conversion chart for D-glucosamine HCL powder here. A serving size of a slightly rounded 1/4 teaspoon is about equal to 1000 mg (1 gram).

Bioavailability, Mixing and Solubility of D-Glucosamine-HCL

D-glucosamine HCL powder is an odorless white crystal with a mild, sweet taste. This product dissolves quickly in water or juice. D-glucosamine HCL is freely soluble in water, slightly soluble in methanol and insoluble in ethanol and related organic reagents. Mix with water, juice or another drink.

How should I store it?

You will receive a resealable bag of this powder. Store in a cool, dry area protected from light. Reseal after each use.

References and Further Research on D-Glucosamine-HCL

University of Maryland Medical Center: Glucosamine

National Center for Complementary and Alternative Medicine: Questions and Answers: NIH Glucosamine/chondroitin Arthritis Intervention Trial Primary Study

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.