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Click to Enlarge Unit Weight: 1500 grams Unit Volume: 2500 cc Click to Enlarge Certificate of Analysis Click to Enlarge Volumetric Equivalents

What is EDTA Disodium?

Edetate disodium (EDTA) is primarily used as a chelating agent. A chelating agent is adept in removing a heavy metal, such as lead or mercury, from the blood. EDTA disodium is used to lower blood levels of calcium when they have become dangerously high, and also in the emergency treatment of hypercalcemia. EDTA is also used to control heart rhythm disturbances and ventricular arrhythmias caused by a heart medication called digitalis (digoxin, Lanoxin). EDTA Disodium forms chelates with polyvalent metals, especially calcium, thus increasing their urinary excretion.

EDTA in general is a substance which removes undesirable metals from the body. Many metals, including lead, mercury, and cadmium are poisonous to the body. Lead and cadmium levels are directly correlated with high blood pressure. EDTA is a chemical compound that binds minerals and metals like chromium, iron, mercury, copper, aluminum, nickel, zinc, calcium, cobalt, manganese, and magnesium to have them removed from the body so as for them to not have any adverse effects on the individual. All metals, even essential nutrients, are toxic if taken in excess or when not situated appropriately. EDTA fixes this by normalizing the distribution of most metallic elements in the body. EDTA improves calcium and cholesterol metabolism by eliminating metallic elements in the body and also by eliminating metallic catalysts which cause damage to cell membranes by producing “oxygen free radicals”. EDTA helps to prevent the production of harmful free radicals, and thus helps prevent atherosclerosis, cancer, diabetes, and other diseases of aging before they can even begin. EDTA Disodium has several synonyms, and is listed in several ways, including: (Ethylenedinitrilo) tetraacetic acid disodium salt, Disodium EDTA, disodium dihydrogen ethylenediaminetetraacetate, disodium edentate, disodium salt, dihydrate, EDTA, EDTA disodium, disodium, Disodium EDTA Violet 2, Disodium EDTE, and Disodiume EDTA.

The term “EDTA” is often used to refer to different drugs that bind to ("chelate") certain molecules within the body. This binding facilitates the elimination of these molecules from the body. For example, EDTA Disodium is injected into the bloodstream; it binds to calcium and speeds excretion of calcium through the kidneys. This type of EDTA compound has been used to manage high levels of calcium in the blood. This drug is approved by the FDA for use in selected patients with high blood calcium levels (hypercalcemia) as well as for use among patients with heart rhythm problems due to digoxin toxicity.

General Advice and Important Note: Do not confuse edetate (EDTA) disodium with edetate calcium disodium (CaEDTA). The former should not be used for lead poisoning, as this error may cause severe hypocalcemia. The two EDTA drugs are easily confused since both are referred to in clinical practice as "EDTA." This confusion has lead in medication errors wherein some patients have been issued the wrong substance, which has been tragic in some cases or caused serious side effects in others. The error is especially dangerous when edetate disodium is erroneously given to patients who are supposed to get edetate calcium disodium.

What is EDTA Disodium used for and who uses it?

The primary function of EDTA Disodium is to remove unwanted metals in particular calcium from vital organs and arteries. EDTA (Ethylenediaminetetraacetic Acid) in general is frequently taken as an oral chelation agent for the reduction of arterial plaque and/or chelation of heavy metals from the body. While oral EDTA Na2 absorption levels are usually less than 10%, clinical studies have consistently shown oral EDTA to be an effective chelation agent for the reduction of arterial plaque. Even at EDTA's low oral absorption rate enough EDTA will enter into the bloodstream to be an effective chelation agent. Many researchers also believe that the unabsorbed EDTA passing through the digestive track will contact and chelate heavy metals from the bile acids thus removing those toxins from the body. Even though a relatively small portion of your oral EDTA dose is absorbed into the blood stream that portion that is not absorbed can be effective as a heavy metal chelation agent. Aside from the principal uses of removing undesirable metals from the body particularly calcium, EDTA Disodium also reverses the process of atherosclerosis, improves cerebrovascular arterial occlusion, improves memory, concentration, and vision, prevents and reverses problems of degenerative diseases, and helps in the treatment of arthritis, scleroderma, lupus, radiation toxicity, snake venom poisoning, digitalis intoxication, and cardiac arrhythmia.

Disodium EDTA is also found in a wide range of personal care products, including contact solution, eye drops, shower and bath products, skin care preparations and cosmetics. It is also used as a preservative and stabilizer in many processed foods and beverages. In medicine, disodium EDTA has medical and laboratory applications including chelating therapy, where EDTA cleanses bodies of excess iron, mercury and other heavy metals; in blood testing and blood transfusions as anticoagulant; in cell proliferation analysis to keep cells separate from each other; and in dental and ophthalmology practices to prime sites for surgery, just to name a few. Disodium EDTA is an important agent in many medical uses and thus it isn't surprising to expect exposure to this chemical compound if you frequent clinics and medical laboratories for tests and treatments listed such as these.

How pure is your EDTA Disodium?

This EDTA Na2 (Ethylenediaminetetraacetic Acid Disodium) is assayed by the manufacturer to be 99.4% Product. You will receive a sealed and labeled heavy duty 4 mil polyethylene bag containing this white crystalline powder product. Due to the fact that our product is pharmaceutical grade, these are best utilized by the body, since they do not require digestion and are easily absorbed. Our product does not contain any fillers, additives or anti-caking agents. If all you want are the health benefits made possible with Disodium EDTA, buying this product in bulk is the best way to get there. Buying in bulk is also your best bet for saving money because for sure you’ll pay more at a local nutrition store. Bulk costs are cheaper in the long run and you will receive a great deal at or below wholesale prices for a high purity bulk quantity of this product.

What is the daily suggested dose of EDTA Disodium?

Oral daily dose recommendations for EDTA Disodium vary considerably from as little as 250 mg to as much as 5 grams for a 170 pound adult, depending upon individual needs. One level teaspoon will supply approximately 3527 milligrams, or just about 3.5 grams for the bulk density of this EDTA Disodium powder. You can see the full bulk density/volumetric conversion chart for EDTA Disodium here. For oral chelation purposes your optimal single dose should be approximately 1 gram EDTA Na2 per 100 pounds of body weight. For example, a 200 pound male or female would have an optimal single dose of approximately 2 grams taken three times per day for a total EDTA daily dose of 6 grams.

Potential side effects of EDTA Disodium

This recommended dose of 1 gram per 100 pounds of body weight may or may not be suited to all individuals. EDTA Na2 in higher doses and occasionally at doses approximating this recommended dose may cause gastric upset and/or nausea is some individuals. Your personally optimal dose for EDTA Na2 may by more or less than the recommended dose depending upon your tolerance and accommodation to this product when taken during fasting periods. Although many pro-natural organizations claims that it causes toxicity in mammals, in products regulated by the FDA, levels of disodium EDTA are too low to cause direct harm when products are used as directed. The only time to be very wary of disodium EDTA content is in processed foods and beverages, where disodium EDTA in reaction with active and unstable ingredients like Vitamin C and sodium Bicarbonate (baking soda) forms benzenes, a potent carcinogen.

Taste, Solubility, and Preparation needed for EDTA Disodium Supplementation

EDTA Na2 powder does not have an unpleasant taste (a little salty tasting perhaps) and can be taken orally with juice or water. Bear in mind, however, that EDTA will dissolve best in hot and slightly alkaline water (with pH above 7.2) and EDTA Na2 will not dissolve readily in acidic water or acidic juices such as citrus juices and drinks or lemonade. While a few EDTA sellers recommend taking this product sublingually for greater absorption, sublingual administration of this EDTA Na2 powder is not necessary and can be a challenging and an unpleasant experience owing to EDTA's positive heat of solution (it gives off heat as it dissolves). Taking EDTA Na2 orally by dissolving it in a glass of warm or hot water and drinking is by far the easiest and most practical way to take oral EDTA in this author's opinion.

Taking your EDTA Na2 doses while fasting is the most effective way to assure the highest absorption rates and the greatest chelation benefits from this product. Since EDTA Na2 is a very effective chelation agent it will bind with whatever minerals you have in your digestive tract if you take it with food or meals. For greatest effect you should take your EDTA Na2 doses three times per day while fasting. The first dose should be taken upon waking in the morning at least one half hour prior to breakfast. Your second dose should be taken in the afternoon at least 2 hours after lunch and at least one hour before dinner. Your third dose should be taken at least 2 to 3 hours after dinner or as close to your bedtime as practical.

Possible Interactions with EDTA Disodium

EDTA Disodium is contraindicated in patients with anuria. Because EDTA Na2 is a very effective mineral chelation agent you will want to avoid taking mineral supplements with or at the same time as your EDTA Na2 doses. Mineral supplements can and should be taken with meals if you take your EDTA dose between meals (during your fasting periods), but you may want to take a full spectrum mineral supplement that includes the minerals Calcium, Magnesium, Zinc, Chromium and Selenium. You may also consider taking your EDTA Na2 chelation doses for one week and then go off for one week while alternating your mineral supplementation during your non-EDTA weeks.

EDTA Disodium is used in the following Proprietary Formulas

Biorad Edta Disodium Dihydrate, PlusOne™ EDTA (GE Healthcare), Wonderlabs EDTA disodium chelate, Angioprim

References & Further Research

Chelation therapy for coronary heart disease: An overview of all clinical investigations
Chelation therapy is popular in the United States. The aim of this systematic review was to summarize all the clinical evidence for or against the effectiveness and efficacy of chelation therapy for coronary heart disease.

EDTA Chelation Therapy in the Treatment of Vascular Disease
Ethylenediamine tetraacetic acid (EDTA) chelation therapy has been used for decades for the treatment of vascular disease, alone or in combination with other treatments. This article includes a historic review of the research literature, current evidence of effectiveness, potential mechanisms of action of EDTA, and some brief case reports. The authors conclude that EDTA chelation therapy is a valuable therapeutic option for vascular disease, either alone or in conjunction with standard treatment protocols.

EDTA Disodium for International Customers

We have the most economical shipping costs & labeling practices for International orders. You can see our shipping costs here. Also, please note, that anything in a 1.5kg package can be shipped within a single flat rate envelope, however our shopping cart mistakenly displays 2 envelopes. Go ahead and ship the order, and you will notice that it only charges you the cost of 1 anyway. Look at the shipping costs tab above to see for yourself how you can calculate these charges.

Buying EDTA Disodium Bulk or Wholesale

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