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What is Ferrous Gluconate?

Ferrous Gluconate is a salt of gluconic acid and elemental iron. As an ionic compound, Ferrous Gluconate consists of one atom of iron for every two molecules of gluconate (glucose). Ferrous Gluconate is a popular iron supplement because of its high bioavailability (high bioavailability) and gentleness on the gastrointestinal (GI) tract. Ferrous Gluconate powder synonyms include: Iron (II) di-D-gluconate powder, Iron (II) Gluconate Powder and Iron(2) Gluconate Powder. In supplements iron comes in various forms with the highest absorption rate being ferrous succinate or sulfate. Ferrous sulfate however can cause gut irritation. A good alternative to this is ferrous gluconate, which is easily absorbed without causing stomach pains. Also, since it is easily absorbed, you wouldn't need as high a dosage for this to be effective, compared to the other salts or forms. In the human body iron is kept primarily in bone marrow, the spleen, and the liver.

Iron supplements belong to a group of medications known as anemia therapy. Iron is available for oral use in different salt forms, which includes ferrous gluconate, ferrous sulfate, and ferrous fumarate. Iron is of paramount importance to make the production of red blood cells possible. It helps red blood cells bring oxygen to where it is needed and also to the various parts of the body. When the body is not able to get sufficient oxygen to use due to lack of iron, symptoms such as tiredness, shortness of breath and learning problems may occur, which leads to iron deficiency anemia. Iron preparations are made especially to treat this condition when sufficient iron is not readily available from the diet. It can also be used to supply iron during times or processes when the body needs extra, for example pregnancy, bleeding problems, burns, and certain stomach problems.

Iron is an important component of proteins necessary in oxygen transport and metabolism. Iron is also a critical ingredient in the synthesis of neurotransmitters such as dopamine, norepinephrine, and serotonin. About 15 percent of the body's iron is stored for future needs and mobilized when dietary intake is inadequate. The body usually maintains normal iron status by controlling the amount of iron absorbed from food, since we normally get iron from the foods we eat. There are two types of dietary iron: heme and non-heme. Good possible sources of heme iron include meat, fish and poultry. Sources of non-heme iron, which is not absorbed as well as heme iron, include beans, lentils, flours, cereals, and grain products. Other sources of iron include dried fruit, peas, asparagus, leafy greens, strawberries, and nuts. Iron deficiency can be determined by checking serum ferritin levels, which can also help differentiate between iron deficiency anemia and anemia associated with chronic disease.

What is Ferrous Gluconate used for and who uses it?

Ferrous Gluconate can help prevent or treat what is commonly known as low blood or more accurately, low levels of iron in the blood. It works by supplementing and replenishing iron in your body if your system does not produce enough on its own. Ferrous gluconate is a type of iron used to treat iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body. In the human body, iron becomes a part of hemoglobin and myoglobin. Hemoglobin transports oxygen through your blood to tissues and organs. Myoglobin aids your muscle cells store oxygen. Iron is essential to nutrition because it is needed to make hemoglobin, the protein that carries oxygen in the blood. The need for iron is heightened during growth, menstruation, pregnancy or when there is a loss of blood or a poor diet. Oral iron supplements are the most efficient way to restore iron levels for people who are iron deficient, but they should be used with caution and only after dietary measures have failed.

Iron is best known for its role as oxygen transporter within the protein hemoglobin. Red blood cells containing hemoglobin moves oxygen to various tissues as it passes through the lungs, largely because of the oxygen binding characteristic of iron. Myoglobin, which contains iron as well, is essential for all bodily tissues and their cellular activity because it carries and stores oxygen in cells. Every 120 days or 2 months, red blood cells and the iron they contain are replaced and recycled. Also, numerous enzymes involved in metabolism require iron to function. Iron is required for protein metabolism as well as cell division (mitosis) and development because of its role in DNA synthesis. Iron is also an integral part in connective tissue production, neurotransmitters, immune system maintenance, and in the production of thyroid hormone.

Only about 5-10 percent of the iron in our diets is retained and synthesized by our bodies. Hem-iron, the organic iron derived from meats, has a much better absorption rate than "non heme". This is where sugars and amino acids come in, because they may boost absorption. Female athletes, endurance athletes, and athletes on low-calorie diets are more susceptible to deficiency. Iron deficiency is also one of the most prevalent nutritional deficiencies in the US. Deficiency symptoms that are treated or alleviated by Ferrous Gluconate include fatigue, rapid heartbeat, breathlessness, lack of concentration, giddiness, disturbed sleep, severe menstrual pain and bleeding, cracked lips, eye inflammation, mouth ulcers, hair loss, and anemia.

How pure is your Ferrous Gluconate?

This Ferrous Gluconate Powder is assayed by the manufacturer to be 98.7% product. You will receive a sealed and labeled heavy duty 4 mil polyethylene bag containing this light green powder. It contains no fillers, taste additives, or anti-caking agents. The remaining 1.3% by weight are inactive byproducts of the extraction.

This medication is an iron supplement used to treat or prevent low blood levels of iron (e.g., for anemia or during pregnancy). Iron is an important mineral that the body needs to produce red blood cells and keep you in good health. Iron, one of the most abundant metals on Earth, is essential to most life forms and to normal human physiology. Iron is an integral part of many proteins and enzymes that maintain good health. In humans, iron is an essential component of proteins involved in oxygen transport. It is also essential for the regulation of cell growth and differentiation. Iron supplementation is indicated when diet alone cannot restore deficient iron levels to normal within an acceptable timeframe. Supplements are especially important when an individual is experiencing clinical symptoms of iron deficiency anemia.

What is the daily suggested dose of Ferrous Gluconate?

Supplemental iron is available in two forms: ferrous and ferric. Ferrous iron salts (ferrous fumarate, ferrous sulfate, and ferrous gluconate) are the best absorbed forms of iron supplements. Elemental iron is the amount of iron in a supplement that is available for absorption. The amount of elemental magnesium in a compound influence the effectiveness of the iron supplement.

Because ferrous gluconate is about 11.5% elemental iron, taking 100 milligrams of ferrous gluconate powder in a single dose will yield 11.5 milligrams elemental iron. You can see the full bulk density/volumetric conversion chart for Ferrous Gluconate here.

Recommended Dietary Allowances for Iron for Children, and Adults (mg/day)
1 to 3 years 7 (mg/day)
4 to 8 years 10
9 to 13 years 8
14 to 18 years 11
19 to 50 years 8
51+ years 8

As always, if you have concerns or questions, consult a physician or a health care professional before taking any supplements. Before taking any kind of medicine, check with your doctor to ensure that the supplement you want to take is right for you. You may be allergic or you may have a sensitive stomach which may raise the need for special instruction as far as dosage goes.

Precautions and Potential side effects of Ferrous Gluconate

Excessive use can cause abdominal cramping, diarrhea, constipation, nausea, deterioration of the gut lining, liver damage, and may increase your chances of acquiring atherosclerosis and heart disease. Take ferrous gluconate on an empty stomach, at least 1 hour before or 2 hours after a meal. Avoid ingesting antacids or antibiotics within 2 hours before or after taking ferrous gluconate. Ferrous gluconate can stain your teeth, but this effect doesn’t last very long. As a workaround to prevent this staining, mix ferrous gluconate with water or fruit juice (not with milk) and drink the mixture through a straw. Alternatively you may also clean your teeth with baking soda once per week to treat any tooth staining.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

Taste, solubility, and appearance of Ferrous Gluconate

Ferrous Gluconate Powder has a characteristically irony (or rusty mineral like) taste and is also somewhat sour. Ferrous Gluconate Powder does not readily dissolve in water by it will suspend into a somewhat cloudy mixture when stirred. Just measure and stir your usual dose into water or juice and drink.

Ferrous Gluconate is used in the following Proprietary Formulas

Meijer Ferrous Gluconate, Mason Natural Ferrous Gluconate, DexFerrum®, Femiron®, Feosol Caplets®, Feosol Tablets®, Feostat®, Feostat Drops®, Feratab®, Fer-gen-sol®, Fergon®,Fer-In-Sol Drops®, Fer-In-Sol Syrup®, Fer-Iron Drops®, Fero-Gradumet®, Ferospace®, Ferralet®, Ferralet Slow Release®, Ferralyn Lanacaps®, Ferra-TD®, Ferretts®, Ferrlecit®, Fumasorb®, Fumerin®, Hemocyte®, Hemofer®, Hytinic®, InFeD®, Ircon®, Mol-Iron®, Nephro-Fer®, Niferex®, Niferex-150®, Nu-Iron®, Nu-Iron 150®, Simron®, Slow Fe®, Span-FF®, Venofer®.

References & Further Research

Fortifying Milk with Ferrous Gluconate and Zinc Oxide in a Public Nutrition Program Reduced the Prevalence of Anemia in Toddlers
This study aimed to assess the efficacy of whole cow's milk fortified with ferrous gluconate and zinc oxide, along with ascorbic acid, in reducing the prevalence of anemia and improving iron status of low income children 10–30 mo of age. Data from the research demonstrated Ferrous gluconate added to whole cow's milk as a fortificant along with ascorbic acid is efficacious in reducing the prevalence of anemia and in improving iron status of Mexican toddlers.

Effectiveness and tolerability of oral liquid ferrous gluconate in iron-deficiency anemia in pregnancy and in the immediate post-partum period: comparison with other liquid or solid formulations containing bivalent or trivalent iron
This has shown that preparations containing ferrous salts (+2) are more easily absorbed than those containing ferric salts (+3) since the former can be immediately absorbed by the duodenal mucosa. The study reported here reveals that oral ferrous gluconate in liquid form is more effective and above all better tolerated than other solid or liquid formulations containing elementary iron.

Ferrous Gluconate for International Customers

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