PureBulk

What is Glutathione Reduced?

Glutathione is a crystalline and water soluble tripeptide composed of the amino acids glutamate, cysteine and glycine. It exists in reduced and oxidized forms. Purebulk offers the reduced form (conventionally called glutathione and abbreviated GSH). The oxidized form is known as glutathione disulfide or GSSG.

Reduced glutathione tripeptide works as an antioxidant, protecting tissue by neutralizing free radical molecules in the body that can damage cell membranes.

Glutathione is present inside cells mainly in its reduced GSH state. GSH synthesis is dependent on the availability of substrates, with cysteine being the most critical. Aside from cysteine, vitamin B6, riboflavin, niacinamide, selenium, glutathione reductase and lipoic acid are all compounds necessary for generating and maintaining adequate levels of reduced glutathione within the body.

Glutathione plays crucial roles in catalysis, metabolism, signal transduction, gene expression and apoptosis. It protects the immune system by promoting antigen presentation and stimulating CD8 cells. Glutathione is directly involved in protecting the liver.

Glutathione is involved in amino acid transport across cell membranes (the g-glutamyl cycle) and is a part of the peptidoleukotrienes. It serves as a cofactor for some enzymatic reactions and as an aid in the rearrangement of protein disulfide bonds.

Glutathione is widely found in fresh and frozen fruits and vegetables, fish and meat. Plant sources rich in glutathione include asparagus, avocado and walnuts.

Benefits of Glutathione Reduced

Glutathione Reduced (GSH) is the body’s most abundant natural antioxidant. It helps turn carbohydrates into energy and inhibits the accumulation of oxidized fats. On the cellular level, glutathione facilitates the transport of important nutrients across cell membranes while supporting the integrity of red blood cells.

Sufficient levels of glutathione are required to support the immune system. Glutathione is also necessary for replication of the lymphocyte immune cells.

Purity and Concentration of Glutathione Reduced

Purebulk's glutathione reduced contains no fillers, taste additives or anti-caking agents.

Potential Side Effects of Glutathione Reduced

There are no known or documented side effects or interactions with oral administration of glutathione if used as directed.

Suggested use of Glutathione Reduced

The suggested serving size for glutathione ranges from 50 milligrams to 500 milligrams daily, depending on individual needs. A typical serving size is 500 milligrams. It is best taken with food, at mealtime. You can see the full bulk density/volumetric conversion chart for Glutathione Reduced here. A serving size of 50 mg will need to be measured on a milligram scale, which PureBulk also sells. A serving size of 1/8 teaspoon equals 275 milligram (mg). For a serving size of 500 mg take a little less than 1/4 teaspoon.

Bioavailability, Mixing and Solubility of Glutathione Reduced

Glutathione has almost no taste and dissolves quickly in water. Mix with water or add it to your favorite juice or smoothie.

How should I store it?

You will receive a resealable bag of this powder. Store in a cool, dry area protected from light. Reseal after each use.

References & Further Research

The American Journal of Clinical Nutrition: Polyphenols and glutathione synthesis regulation

Wikipedia: Amino Acids

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.

Other Purebulk Products of Interest

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