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Click to Enlarge Unit Weight: 1500 grams Unit Volume: 2000 cc Click to Enlarge Certificate of Analysis Click to Enlarge Volumetric Equivalents

What is L-Alanine?

Alanine, or L-alanine, is an amino acid that makes it possible for the body convert the simple sugar glucose into energy and dispose toxins from the liver. Amino acids are the building blocks of protein, and are key to building strong, healthy muscles—alanine has been shown to help protect cells from being damaged during intense aerobic activity, when the body cannibalizes muscle protein to help produce energy. It helps regulate and maintain healthy blood sugar levels to prevent chronic deficiencies that may cause muscle loss and poor glucose tolerance.

Alanine is a nonessential amino acid, as it is synthesized in the body in muscle tissue from branched chain amino acids such as valine, leucine, and isoleucine. This means since it is manufactured from other amino acids in the liver, it does not have to be obtained directly through the diet and a healthy body is able to manufacture its own supply of this substance. Alanine can also be manufactured in the body from pyruvate. Alanine is found in a wide selection of dietary sources, but it is particularly concentrated in meats. Other excellent food sources of alanine include beans, poultry, nuts, dairy products, seafood, seeds, soy, whey, brewer's yeast, brown rice bran, caseinate, corn, dairy products, eggs, fish, gelatin, legumes, and whole grains. Other protein-rich plant foods like avocado can provide alanine as well.

Alanine is of paramount importance for preserving balanced levels of nitrogen and glucose in the body. Through a series of chemical actions called the alanine cycle, any excess amino acids (proteins) in cells or tissues are transferred to a receptor molecule called pyruvate, which is made by the breakdown of glucose. The pyruvate is then converted to alanine and transported to the liver. The liver takes nitrogen from alanine and changes some of it back into pyruvate, which can then be used to produce more glucose. Any leftover nitrogen is then converted into urea and excreted during urination. This cycle of glucose breaking down to pyruvate then alanine then pyruvate then glucose again, is critical for the body for it to get the energy it needs to support cellular life. In essence Alanine is used by the body to draw upon blood sugar as an energy source. It also ensures that a steady supply of pyruvate is bioavailable to promote the synthesis of glucose and amino acids in the body.

What is L-Alanine used for and who uses it?

Alanine is a vital source of energy for muscle tissue, the brain and central nervous system. It strengthens the immune system by producing antibodies, and helps in the metabolism of sugars and organic acids as well. Everyone, from top-level athletes to ordinary people, needs L-alanine. Since alanine is utilized by the body to derive an energy source from blood sugar, it may prove beneficial for bodybuilders and other athletes who are attempting to reduce body fat levels. It supports the metabolism of glucose, a simple carbohydrate that the body uses for energy. For the same reason, obese or overweight individuals may benefit by using a supplement containing alanine. During strenuous exercise L-Alanine is made available for muscle tissues into systemic circulation, where it gets converted to pyruvate in the liver, after which it evolves into glucose again for increased energy and endurance during grueling physical exertions and trainings. This makes L-Alanine an excellent addition to many pre-workout energy drink and shakes because it serves as fuel for the muscles to increase power, strength and endurance for many performance athletes, especially strength athletes like powerlifters and body builders.

Alanine also guards against the buildup of toxic substances that are released in the muscle cells when muscle protein is broken down to quickly meet energy needs, which is what happens with aerobic exercise. Individuals suffering from hypertension may benefit from supplemental alanine because it has demonstrated a cholesterol-reducing effect in clinical studies done on rats. When used together with arginine and glycine it has been shown that an overall decrease in arterial plaque may result.

Diabetics, or individuals suffering from insulin insensitivity, can get some much needed help from alanine supplementation because alanine has been shown to be integral in the regulation of insulin. Research and studies conducted have concluded and found has found that taking an oral dose of L-alanine for people with insulin-dependent diabetes effectively prevents nighttime hypoglycemia. In cases of hypoglycemia (low blood sugar), alanine has been considered a reliable source for the production of glucose in order to regulate and maintain healthy and optimal blood sugar levels over longer periods. Alanine is also useful in improving prostate health. Because alanine is present in the prostate gland fluid, it has been theorized that this amino acid may help treat benign prostatic hyperplasia (BPH), a condition in which the prostate becomes enlarged and causes pain during urination. Because of this, elderly males may benefit from its use. In one study, participants with BPH used 780 milligrams of alanine, glycine, and glutamic acid daily for two weeks, then 390 milligrams of these amino acids for the next two and a half months, and saw a significant improvement in their health by a reduction in symptoms present before.

How pure is your L-Alanine?

This pharmaceutical grade pure bulk powder amino acid L-Alanine is assayed by the manufacturer to be 99.38% product. You will receive a sealed and labeled heavy-duty 4 mil polyethylene bag containing this white powder product. Most people do not need to supplement with alanine since it is well provided for in many diets, and can be synthesized from pyruvic acid (formed in the breakdown of carbohydrates). However, if you are among the many people who are on a very low protein diet, you could be at risk of a deficiency. Due to the fact that our product is pharmaceutical grade, these are best utilized by the body, since they do not require digestion and are easily absorbed. Our product does not contain any fillers, additives or anti-caking agents. If all you want are the health benefits made possible with L-Alanine, buying this product in bulk is the best way to get there. Buying in bulk is also your best bet for saving money because for sure you’ll pay more at a local nutrition store. Bulk costs are cheaper in the long run and you will receive a great deal at or below wholesale prices for a high purity bulk quantity of this product.

Alanine is a nonessential amino acid, however, all amino acids can become essential, thus requiring dietary supplementation, if the body is for some reason unable to produce them in significant amounts. Those who eat low-protein diets or possess eating disorders, liver disease, diabetes, or genetic conditions that cause Urea Cycle Disorders (UCDs), are more susceptible to a deficiency, but this may be averted by taking alanine supplements. Low levels of alanine is something all patients with hypoglycemia, diabetes, and hepatitis share, although more studies are needed to know if alanine deficiency is the cause or result of these diseases. The body must always have alanine available for it to be able to process the B vitamins necessary for proper health, especially vitamin B5 (pantothenic acid) and vitamin B6 (pyridoxine). Most people do not need to supplement with alanine; for those who do use this amino acid as a supplement, right amounts should be determined with the advice of a physician.

What is the daily suggested dose of L-Alanine?

The typically recommended dose for L-Alanine ranges between 3 and 10 grams taken 30 minutes before your strenuous physical workout. For bodybuilders and performance athletes one half level tablespoon will supply approximately 6031 milligrams, or just about 6 grams for the bulk density of this L-Alanine powder. You can see the full bulk density/volumetric conversion chart for L-Alanine here.

What kind of results do people anticipate while taking L-Alanine?

During exercise the muscles release alanine into the bloodstream at a rate directly proportional to the intensity of the exertion. The alanine then evolves into glucose and released into the blood plasma. Alanine may help keep blood sugar levels stable during exercise. Glucose can be made from alanine in the liver or muscles when energy is needed, and thus it may help maintain the blood sugar level. Low levels of blood sugar have been linked with fatigue during exertion, which is why many experts think alanine supplements might enable athletes to exercise for longer periods of time at competitive intensities.

Potential side effects of L-Alanine

No side effects have been reported, although as with any amino-acid, overdose is a possibility. Individuals suffering from diabetes, prostatitis or hypertension should consult a qualified medical practitioner prior to the use of supplemental L-alanine. High levels of alanine, along with low levels of tyrosine and phenylalanine, have been associated with the Epstein-Barr virus and chronic fatigue syndrome. Keep in mind that although Alanine by itself does not have any side effects, taking any one amino acid could upset the balance of nitrogen in the body, and make it harder for the liver and kidneys eliminate waste. As such, people with liver or kidney disease should not consume high amounts of amino acids without consulting a health care professional first.

Taste, solubility, and suggested preparation of L-Alanine

This product dissolves quickly in water and has a pleasantly sweet taste. L-Alanine makes an excellent addition to your pre-workout or energy drink or protein shake.

L-Alanine is used in the following Proprietary Formulas

Optimum Superior Amino 2222, MuscleTech IntraVol, Twinlab Amino Fuel Liquid, Universal Natural Sterol Complex, Ultimate Nutrition Super Amino 2000, All American EFX NF-Pro, All The Whey Whey Protein Concentrate, ALRI Chain'd Out, Beverly Int. Mass, Beverly Int. Up-Lift, Champion Vita-Vault, Endurox Excel Electrolyte Replenisher, Enzymatic Therapy Energy Revitalization System, German American Technologies Amino 2100, Hammer Nutrition PSA Caps, Higher Power M3 Muscle Bound, John Scott's Nitro Amino Armor, KAL Amino Acid Complex 1000, LA Muscle LA Whey, Metabolic Diet Resolve Competition, MHP A-Bomb, Muscle Gauge Nutrition Recovery 911, Muscle Pharm Combat Powder, Muscleology Nitro-Pro, Next Generation Labs Finotrenbolone, Nimbus Nutrition Performance Post-Workout, Nimbus Nutrition Performance Protein Isolate, NPS VirMAX DS MAXimum Performance Enhancer For Men, NRG-X Labs Anabolic Raptor, NuCare NuBlend Whey, NxLabs AminoVol, Prolab Amino 2000, S.A.N. CM2 Nitrate, S.A.N. Myotein, SciFit Amino Infusion 5000, SciFit Muscle Smoothie, Shocker Nutrition AlphaMale, Techline Vita Tech, Twinlab Amino Fuel Tablets, Twinlab Brewers Yeast, Twinlab Mass Fuel Xtreme, Universal Lava, Universal Prostate Support, Weider Amino 6000,

References & Further Research

Effects of exercise on protein and amino acid metabolism
Some amino acids contribute to exercise energy needs. Although a number of mechanisms have been suggested, the current evidence strongly suggests that the branched-chain amino acids (glucose-alanine cycle) are the most important. In conclusion, recent investigations employing both humans and laboratory animals suggest that protein/amino acids, under some conditions, may contribute significantly to total exercise calories.

Amino acid and protein metabolism during exercise and recovery
The integrated use of several energy sources allows high muscular power outputs to be sustained. Muscle glycogen provides the major fuel source for muscular exercise, but other fuels can provide alternative energy sources which allow for muscle glycogen-sparing and an increased potential for prolonged high metabolic rates. Several amino acids, including the essential amino acid leucine, are also used directly as oxidizable fuels during exercise. Alanine, along with lactate and pyruvate, are recognized as the major gluconeogenic precursors. During exercise and recovery, amino acids likely play important anaplerotic functions sustaining the whole metabolic apparatus.

L-Alanine for International Customers

We have the most economical shipping costs & labeling practices for International orders. You can see our shipping costs here. Also, please note, that anything in a 1.5kg package can be shipped within a single flat rate envelope, however our shopping cart mistakenly displays 2 envelopes. Go ahead and ship the order, and you will notice that it only charges you the cost of 1 anyway. Look at the shipping costs tab above to see for yourself how you can calculate these charges.

Buying L-Alanine Bulk or Wholesale

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