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What is L-Arginine Alpha-Ketoglutarate (AAKG)?

Arginine alpha-ketoglutarate (AAKG) is a salt formed by combining two molecules of the amino acid Arginine and one molecule of alpha-ketoglutarate. Since AAKG is directly involved in amino acid synthesis and protein availability, many athletes supplement with AAKG as a way to increase muscle mass and strength. It is found in high concentrations in nuts and seeds like peanuts and almonds. It can also be found in chocolate and dairy products.

AAKG is a very well-known supplement for body builders and performance athletes wanting to increase Nitric Oxide (NO) production for increased muscle pump. Through the use of AAKG, strength athletes from powerlifters to bodybuilders can attain huge muscle gains and sports athletes can realize huge performance gains. AAKG is a major ingredient in many body building formulations and as such tens of thousands of bodybuilders and performance athletes supplement their diets and trainings with AAKG. AAKG supplementation is also recommended by many physicians and health practice professionals for cardiac health.

Arginine is a conditionally “essential” amino acid which means during heavy training cycles inadequate amounts are synthesized in the liver from other amino acids. As such Arginine must be supplied to the body from crude proteins and supplements. Arginine has a known role in natural Growth Hormone production, sperm production and motility and natural creatine production. Arginine also acts as a precursor to Nitric Oxide NO2. Nitric Oxide (NO2) is a very powerful vasodilator that increases the intensity and duration of the "pump" which is gained when working out (usually after heavy weights). Most users experience an almost immediate increase in vascularity and pump shortly after taking AAKG. Creatine Ethyl Ester (CEE), which we also carry in our inventory, combined with AAKG, makes an excellent stack for a very effective and powerful muscle-building combination.

What is AAKG used for and who can benefit the most from using it?

AAKG promotes increased nitric oxide (NO) production, thus enhancing blood flow, which in turn leads to better delivery of oxygen and nutrients to working muscle. AAKG creates an anabolic or muscle building environment in your body by hemodilation, or increasing the volume of blood flowing through muscle tissue. This results to an increased oxygen and nutrient delivery, better glucose uptake, and improved muscle velocity and power output. AAKG in essence increases muscle size and strength, reduces body fat, and stimulates the immune system. The increased blood flow may also contribute to enhanced sexual performance.

AAKG is used by many elite power and strength athletes who show deficiency of arginine within the body as it is used unsparingly for natural creatine production. Aside from people engaged in serious strength training, AAKG has been used to treat patients suffering from burns, surgery, malnutrition and other trauma. Although the precise mechanism is unknown, AAKG treatment decreases muscle protein catabolism (breakdown) and/or increases protein synthesis, in addition to promoting wound healing. AAKG may promote the secretion of anabolic hormones such as insulin and growth hormone and increase amino acid metabolism (glutamine & arginine), which may help explain some of the clinical findings.

How pure is your AAKG powder?

This pharmaceutical grade amino acid L-Arginine alpha-Ketoglutarate (2:1) assayed by the manufacturer to be 98.2% product. You will receive a sealed and labeled heavy duty 4 mil polyethylene bag of this white powder product. Due to the fact that our product is pharmaceutical grade, these are best utilized by the body, since they do not require digestion and are easily absorbed. Our product does not contain any fillers, additives or anti-caking agents. If all you want are the health benefits and muscle mass gains made possible with AAKG, buying this product in bulk is the best way to get there. Buying in bulk is also your best bet for saving money because for sure you’ll pay more at a local nutrition store. Bulk costs are cheaper in the long run and you will receive a great deal at or below wholesale prices for a high purity bulk quantity of this product.

What are some of the common effects of AAKG powder?

Aside from being an effective NO2 supplement, the key benefits of Arginine Alpha Ketoglutarate (AAKG) also include increased muscular pump and heightened energy levels. Used in conjunction with an exercise program, AAKG may support myodilation, the expansion of muscle tissue. AAKG is a more bio-available form of Arginine (or L-arginine) which is a crystalline free-form amino acid involved in numerous areas of body processes, including muscle metabolism, ammonia detoxification, hormone secretion and the immune system. Arginine supports protein synthesis as it is involved in the transport and storage of nitrogen and is important for proper physical performance because it is used by the body to produce creatine.

Arginine is also useful in the treatment of medical conditions that are improved by vasodilation, such as angina, atherosclerosis, coronary artery disease, erectile dysfunction, heart failure, intermittent claudication/peripheral vascular disease, and vascular headache. Arginine also aids protein synthesis and has been studied for wound healing, bodybuilding, and increasing sperm production (spermatogenesis). L-Arginine is beneficial for overall cardiovascular maintenance and sexual function as well as other areas that depend on a healthy circulatory system.

Potential side effects of AAKG

Arginine Alpha-Ketoglutarate is a safe supplement, and its benefits are well documented through research and sports like bodybuilding for decades now. However, overuse and large doses of AAKG can lead to problems that include upset stomach, restlessness and insomnia. Some report that ingesting AAKG before bed can cause difficulty falling asleep. If you experience such problems, either reduce your bedtime dose or avoid taking AAKG powder within 4 to 6 hours of your bedtime.

Although there is no known toxicity of Arginine Alpha-Ketoglutarate, just for good measure anyone who wants to supplement with arginine with existing heart or psychiatric conditions should consult with their doctor prior to using any arginine-based product.

Taste, solubility, and daily recommended dose of AAKG

This product dissolves quickly in water and has a slightly sour taste, but can be added to your protein shakes or mixed with juice to make it more palatable and easier to ingest.

The typically recommended dose for AAKG varies between 2 grams and 15 grams per day, depending upon individual needs. For bodybuilders and performance athletes one half level tablespoon will supply approximately 3969 milligrams, or just about 4 grams for the bulk density of this AAKG powder. You can see the full bulk density/volumetric conversion chart for AAKG here. Taking 1/2 level tablespoon 3 times per day will supply a total daily dose of 12 grams. For individuals wanting to supplement with AAKG for their general cardiac and cardiovascular health should consider one level 1/2 teaspoon of approximately 1323 milligrams taken two or three times per day for a total daily dose of between 2 and 4 grams per day. AAKG is not recommended for continuous, high-level use for more than 80 days. Don’t take products that contain ephedrine while using AAKG as they may act as a vasoconstrictor reducing AAKG effects.

AAKG is used in the following Proprietary Formulas

NOW AAKG, 1Fast400 Arginine Alpha Ketoglutarate, Oxegen AKG Nitric Oxide Stimulator, Nitrostack Nitric Oxide, BSN NO-Xplode, Gaspari Nutrition SuperPump250, USPlabs Jack3d, Gaspari Nutrition SizeOn, MuscleTech NaNO Vapor, Creabolan 3rd Generation from Syn-Tec

References & Further Research

Effect of arginine ketoglutarate on the detoxifying capacity of the liver in cirrhosis of the liver
This study have shown that arginine ketoglutarate in sufficiently high dosage (3x3 g daily by mouth) produces a significant lowering of plasma ammonia and free serum phenols with a high-protein diet in patients with liver cirrhosis, compared to a previous day without this substance.

Pharmacokinetics, safety, and effects on exercise performance of L-arginine alpha-ketoglutarate in trained adult men
This study evaluated the pharmacokinetics, safety, and efficacy of l-arginine alpha-ketoglutarate (AAKG) in trained adult men. The researchers were able to conclude AAKG supplementation is safe and well tolerated, and positively influenced 1RM bench press and Wingate peak power performance.

Arginine alpha-ketoglutarate (AAKG) for International Customers

We have the most economical shipping costs & labeling practices for International orders. You can see our shipping costs here. Also, please note, that anything in a 1.5kg package can be shipped within a single flat rate envelope, however our shopping cart mistakenly displays 2 envelopes. Go ahead and ship the order, and you will notice that it only charges you the cost of 1 anyway. Look at the shipping costs tab above to see for yourself how you can calculate these charges.

Buying Arginine alpha-ketoglutarate (AAKG) Bulk or Wholesale

If you need AAKG in bulk or wholesale quantities, please feel free to contact us with sourcing/shipping/fulfilment questions. If you have any questions about shipping or would like to arrange a shipment to an excluded country please use the contact page!

Terms

AAKG, AKG, A-AKG, Arginine AKG, L-Arginine Alpha-Ketoglutarate, Arginine-Alpha-Ketoglutarate, L Arginine Alpha Keto Glutarate, L Arginine Alpha Ketoglutarate, best aakg, aakg powder.