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What is L-Arginine-AKG L-Ornithine-AKG

L-Arginine-AKG L-Ornithine-AKG combines the power of Arginine, with alpha-ketoglutarate (AAKG) and L-ornithine Alpha-ketoglutarate (OKG), and it promotes increased nitric oxide (NO) production for enhanced circulation leading to better delivery of oxygen and nutrients to working muscle. Ornithine alpha-ketoglutarate (OKG) is formed through combination of the amino acid L-Ornithine and alpha-ketoglutarate (AKG). L-Ornithine is used by athletes to improve performance, while AKG is a precursor to the amino acid glutamine and also plays a crucial role in the physiological process known as the Krebs cycle which is responsible for breaking down carbohydrates in your body to produce energy.

L-Arginine-alpha-ketoglutarate (AAKG) is a compound made from the amino acid L-arginine and alpha-ketoglutarate, a substance produced during the body's energy-generating process. L-arginine is known to promote circulation. It's a precursor to nitric oxide (NO), which is a key regulator of vasodilation (the process by which blood vessels dilate, allowing a greater volume of blood to flow through). L-arginine can significantly improve and enhance athletic performance by increasing oxygen supply and nutrient delivery to working muscles. The increased blood flow can also contribute and improve poor sexual performance. Additionally, L-arginine stimulates the production of human growth hormone (HGH), a chemical produced by the body that promotes growth and plays an essential role in metabolism. HGH is popular among athletes because it's believed to play a part in building lean muscle mass and increasing strength.

The amino acids ornithine and glutamine have been chemically added together to create ornithine alpha-ketoglutarate (OKG). OKG has been demonstrated to increase protein retention, speed up wound repair, and improve immune function in hospitalized patients partly by increasing levels of growth-promoting (anabolic) hormones such as insulin and growth hormone. In a large, well-controlled trial, nonhospitalized elderly people benefited from 10 grams per day of OKG as they recovered from various illnesses or surgery, showing improved appetite, weight gain, muscle growth, reduced need for medical care, and improved quality of life. L-ornithine Alpha-ketoglutarate (OKG) is a amino acid compound which enhances performance in hypercatabolic states associated with such activities as strenous sports and weightlifting (powerlifting, bodybuilding, strongman events etc.). L-ornithine and alpha-ketoglutarate work synergistically in hypercatabolic conditions to attain numerous favorable outcomes. OKG lowers the rate at which ammonia accumulates. The nitrogen-sparing quality of OKG may be related to its ability to reduce the rate of glutamine loss, since glutamine has a critical role in protein turnover during the catabolic states. As a result of these series of events, OKG is able to increase endurance, reduce muscle fatigue and shorten recovery time. Additionally, OKG increases production of human growth hormone, which in turn increases muscle mass.

L-arginine is a chemical building block called “an amino acid.” It can be derived from the diet and is necessary for the body to make proteins. L-arginine is found in red meat, poultry, fish, and dairy products. It can also be synthesized in a laboratory and used as medicine. L-arginine is converted in the body into a compound called nitric oxide which causes blood vessels in a process called vasodilation to open wider for improved blood flow. L-arginine also stimulates the release of growth hormone, insulin, and other substances and hormones essential in the proper overall functioning of the body. Because of this L-arginine is used for heart and blood vessel conditions including congestive heart failure (CHF), chest pain, high blood pressure, and coronary artery disease. L-arginine is also beneficial for recurrent pain in the legs due to blocked arteries (intermittent claudication), decreased mental capacity in the elderly (senile dementia), erectile dysfunction (ED), and male infertility. Some people use L-arginine for preventing the common cold, improving kidney function after a kidney transplant, high blood pressure during pregnancy (pre-eclampsia), improving athletic performance, and boosting the immune system.

What is L-Arginine-AKG L-Ornithine-AKG used for and who uses it?

Because L-Arginine-AKG L-Ornithine-AKG seems to be involved in amino acid synthesis and protein availability, many athletes supplement with OKG as a way to increase muscle mass, hormone levels and strength. Taking L-Arginine-AKG L-Ornithine-AKG decreases muscle protein catabolism (breakdown) and increases protein synthesis, in addition to promoting wound healing. L-Arginine-AKG L-Ornithine-AKG fulfills these functions by encouraging the secretion of insulin and human growth hormone, and by up regulating glutamine and arginine production. When given to trauma patients, there are notable improvements in both IGF-1 and growth hormone levels.

L-Arginine-AKG L-Ornithine-AKG is a potent anabolic muscle building food. It enhances and improves energy, endurance and muscle mass while at the same time inhibiting muscle breakdown, fatigue, and the build up of fat. L-Arginine-AKG L-Ornithine-AKG also has the ability to speed up recovery time which is why it has become a popular choice among many athletes. L-Ornithine and alpha-ketoglutarate (AKG) work synergistically in Ornithine alpha-ketoglutarate (OKG) to create a conducive environment for growth and development from most exercise and training regimens, by regulating glutamine levels. L-Glutamine is a primary source of cellular fuel, which makes metabolic processes possible.

L-Arginine-AKG L-Ornithine-AKG also stimulates the growth-promoting action of insulin, which encourages muscle growth and increases strength. It provides the amino acid arginine which triggers your pituitary gland to create and release Growth Hormone (GH). This hormone boosts the metabolism of body fat while at the same time protecting your muscle tissue from being broken down for energy, which results in a leaner appearance. By encouraging the excretion of ammonia (released during exercise), L-Arginine-AKG L-Ornithine-AKG also prevents the build up of lactic acid - known to accumulate with ammonia - which causes muscle fatigue, soreness and poor stamina.

This amino acid plays several roles in the body, such as in wound healing, removing excess ammonia from the body, stimulating immune function, and promoting secretion of certain hormones, including glucagon, insulin, and growth hormone. Severe burns, infections, and injuries can decrease the body’s supply of arginine. It is used in hospitals as a supplement for the immune system to speed up especially for patients coming from intensive care. Arginine can also be used to avert colds, asthma, kidney failure, and improve recovery from illness and injury. This amino acid also helps in the synthesis of proteins synthesis, which consequently leads to an increase in cellular replication. As such, arginine may help people with inadequate numbers of certain cells. In line with this, studies have shown that men with low sperm counts experienced an increase in the number of sperm when they supplemented with arginine.

Some evidence has also shown arginine may significantly help in regulating the cholesterol levels. By reducing platelet aggregation, it makes the blood thin and by increasing the protein synthesis in the body, it helps in the wound healing. Arginine is used to help treat conditions such as congestive heart failure, impotence, sexual dysfunction in women, intermittent claudication and interstitial cystitis as well. Among other functions, Arginine acts as a chemical messenger that is necessary for good memory and learning, as well as in the regulation of the sleep-wake cycle.

How pure is your L-Arginine-AKG L-Ornithine-AKG?

These pharmaceutical grade amino acids, L-Arginine alpha-Ketoglutarate (2:1) and L-Ornithine alpha-Ketoglutarate (1:1) are blended in a ratio of 2 parts AAKG to 1 part OKG and assayed by the manufacturer to be 99.1% product and 96.9% product respectively. You will receive a sealed and labeled heavy duty 4 mil polyethylene bag containing this blended white powder product consisting of 167 grams AAKG and 83 grams OKG (representing a 2 parts AAKG to 1 part OKG blend which is the standard blend ratio for these products). It contains no fillers, taste additives, or anti-caking agents.

What is the daily suggested dose of L-Arginine-AKG L-Ornithine-AKG?

Recommended dose for L-Arginine-AKG L-Ornithine-AKG vary from 2-5 grams daily. One level teaspoon will supply approximately 1925 milligrams, or just about 2 grams for the bulk density of this L-Arginine-AKG L-Ornithine-AKG powder. You can see the full bulk density/volumetric conversion chart for L-Arginine-AKG L-Ornithine-AKG here.

As always, if you have concerns or questions, consult a physician or a health care professional before taking any supplements. Before taking any kind of medicine, check with your doctor to ensure that the supplement you want to take is right for you. You may be allergic or you may have a sensitive stomach which may raise the need for special instruction as far as dosage goes.

Potential side effects of L-Arginine-AKG L-Ornithine-AKG

Side effect from higher doses of L-Arginine-AKG L-Ornithine-AKG principally involve gastric upset. However if you have kidney or liver disease you should consult your physician before taking any supplements. Arginine cannot be suggested as a supplement during pregnancy or breastfeeding because there is not enough scientific information available.

Keep in mind also that higher doses of arginine can increase stomach acid, and as such, this can harm people with heartburn, ulcers, or who are already taking drugs that are harmful to the stomach. Arginine may change and affect potassium levels, especially in people with liver disease. People with kidney problems and those who take ACE inhibitors or potassium sparing diuretics should not use supplemental arginine unless they are under medical supervision from a qualified professional.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

Taste, solubility, and suggested preparation of L-Arginine-AKG L-Ornithine-AKG

This product dissolves quickly in water and has a slightly sour taste, but not bad tasting at all. Just mix your usual dose with water or citrus juice and drink.

L-Arginine-AKG L-Ornithine-AKG is used in the following Proprietary Formulas

Sargenor, Spedifen®, BSN NO-Xplode, Gaspari Nutrition SuperPump250, USPlabs Jack3d, Gaspari Nutrition SizeOn, MuscleTech NaNO Vapor, 4Ever Fit L-Arginine, AllMax Nutrition Arginine, Cheap Supplements Arginine, Higher Power AAKG Powder,Jarrow Formulas Arginine 1000, Natrol L-Arginine, NOW AAKG Powder, Shocker Nutrition N.O. Extreme, Syntrax Nitrous, Twinlab L-Arginine, Ultimate Nutrition Arginine Power

References & Further Research

Influence of chronic supplementation of arginine aspartate in endurance athletes on performance and substrate metabolism
The intake of arginine aspartate has been shown to increase anabolic hormones like human growth hormone (hGH) and glucagon. The aim of this study was to investigate whether daily intake of two different dosages of arginine asparate during four weeks affects selected parameters of overtraining syndrome like performance, metabolic and endocrine parameters.

A pilot study of l-arginine supplementation on functional capacity in peripheral arterial disease
Peripheral arterial disease (PAD) impairs walking capacity and is often associated with a profound endothelial vasodilator dysfunction, characterized by reduced bioactivity and/or synthesis of endothelium-derived nitric oxide (NO). The results showed there was no significant difference observed in absolute claudication distance between the groups. However, a trend was observed for a greater increase in walking distance in the group treated with 3 g L-arginine daily, and there was a trend for an improvement in walking speed in patients treated with L-arginine. This pilot study provided data for safety, for power calculation and for dosing for the larger definitive trial that is now underway.

L-Arginine-AKG L-Ornithine-AKG for International Customers

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Buying L-Arginine-AKG L-Ornithine-AKG Bulk or Wholesale

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