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Click to Enlarge Unit Weight: 1500 grams Unit Volume: 2100 cc Click to Enlarge Certificate of Analysis Click to Enlarge Volumetric Equivalents

What is L-Aspartic Acid?

Aspartic acid, also known as L-aspartate or Asparaginic acid, is found primarily in sugar cane and molasses and is believed to help promote a robust metabolism and is generally used to help treat fatigue and depression. Aspartic acid is of paramount importance in the citric acid cycle, or better known as the Krebs cycle, during which other amino acids and biochemicals, such as asparagine, arginine, lysine, methionine, threonine, and isoleucine, are synthesized. Aspartic acid became well-known as a treatment for chronic fatigue from the crucial role it plays in generating cellular energy. Aspartic acid transports the coenzyme nicotinamide adenine dinucleotide (NADH) molecules from the main body of the cell to its power plant or mitochondria, where it is utilized to generate adenosine triphosphate (ATP), the fuel that powers all cellular activity.

In essence, the more NADH a cell contains, the higher is its potential to produce the chemical fuel needed, to give you the energy you require to get through your day. Some studies have shown that aspartic acid actually increases both stamina and endurance levels in athletes because of its importance in generating ATP. In addition, this amino acid helps in the delivery of minerals where they are needed to form healthy RNA and DNA to the cells, and bolsters the immune system by stimulating increased production of immunoglobulins and antibodies (immune system proteins). Aspartic acid helps to keep your memory sharp by increasing concentrations of NADH in the brain, which is believed to trigger the production of neurotransmitters and chemicals necessary for normal mental functioning. It also aids in the disposal of excess toxins from the cells, particularly ammonia, which is very damaging to the brain and nervous system as well as the liver.

Aspartic acid is one of the nonessential amino acids. "Nonessential" means that our bodies produce it even if we don't get this amino acid from our daily diet or the food we eat. Owing to the fact that L-Aspartate is a non-essential amino acid, this means the body can manufacture its own supply for its needs, thus making a deficiency unlikely. It can also be derived from the diet through dairy, beef, poultry, sugar cane and molasses (the artificial sweetener aspartame is made from aspartic acid and phenylalanine, another amino acid). People with low protein diets, with eating disorders, or those with malnutrition may develop a deficiency not only in aspartic acid, but in other amino acids as well, and experience extreme fatigue or depression. With the use of L-Aspartic Acid, this can be averted since L-aspartic acid plays a vital role in energy production.

What is L-Aspartic Acid used for and who uses it?

Aspartic Acid is beneficial and useful in getting rid of harmful ammonia from the body. When ammonia enters the body’s circulatory system, it acts like a highly toxic substance which can harm the central nervous system. By getting rid of ammonia through the action of Aspartic acid, this leads to liver health benefits by sparing the liver from the stress of having to remove the excess ammonia from the bloodstream. Aspartic acid does this by combining with other amino acids to form molecules that absorb toxins and remove them from the body’s system. Recent studies demonstrate that Aspartic Acid can also improve resistance to fatigue and increase endurance, thus significantly helping people from experiencing chronic fatigue syndrome. Since aspartic acid increases stamina, it is good for fatigue. Chronic fatigue syndrome may result from low levels of aspartic acid, because this can lead to lowered cellular energy.

This free form amino acid L-Aspartic Acid is an excititory neuro transmitter and has a vital role as a necessary component and step in the transport of high-energy NADH (Nicotinamide Adenine Dinucleotide) molecules from the cellular body and into the mitochondria. Supplementation with L-Aspartic Acid increases resistance to fatigue and allows performance athletes and bodybuilders to train harder for longer with greater performance, less fatigue, increased stamina and increased endurance. L-Aspartic Acid is also involved in the synthesis of both RNA and DNA, helps to protect the liver, and helps to strengthen the immune system by enhancing the body's production of immunoglobulin and antiglobulin, key components of a healthy immune system. L-Aspartic Acid is also directly involved in proper fat and/or glucose metabolism and has been studied as a potential treatment for fat and/or glucose metabolic disorders of some overweight or obese individuals. One of the most significant benefits of L-Aspartic Acid involves the role it plays in removing toxic ammonia, a byproduct of the breakdown of muscle tissue caused by strenuous exercise, by converting to urea and the excretion from the body in urine.

How pure is your L-Aspartic Acid?

This pharmaceutical grade amino acid L-Aspartic Acid assayed by the manufacturer to be 99.1% product. You will receive a sealed and labeled heavy-duty 4 mil polyethylene bag containing this white powder product. It contains no fillers, taste additives, or anti-caking agents. This L-Aspartic Acid powder is a free form of the amino acid aspartate meaning that it is the most basic form without any additional chemical groups attached. This free form L-Aspartic Acid is therefore somewhat more potent and concentrated with aspartate than all other L-Aspartic Acid analog molecules. For individuals that want the most L-Aspartic Acid for their money, or want to encapsulate their L-Aspartic Acid supplement, this pure bulk powder ranks high among the most potent and economical L-Aspartic Acid supplements available.

What is the daily suggested dose of L-Aspartic Acid?

The commonly recommended dose for L-Aspartic Acid Powder is from 2-6 grams per day, depending upon individual needs, and taken in divided doses between meals. For bodybuilders and performance athletes a 1/2 level teaspoon (approximately 1926 milligrams) two or three times per day (totaling about 4 grams to 6 grams per day) between meals is sufficient. You can see the full bulk density/volumetric conversion chart for L-Aspartic Acid here.

As always, if you have concerns or questions, consult a physician or a health care professional before taking any supplements. Before taking any kind of medicine, check with your doctor to ensure that the supplement you want to take is right for you. You may be allergic or you may have a sensitive stomach which may raise the need for special instruction as far as dosage goes.

Precautions and Potential side effects of L-Aspartic Acid

Aspartic acid, or otherwise known as aspartate, can work as an excitotoxin in the human body. Ideally, aspartate acts as a neurotransmitter in the brain. However, as with other excitotoxins, too much aspartate in the brain can be harmful to some brain cells when they become over stimulated or over saturated. This slow damaging of neurons can lead to Parkinson's disease and memory loss as well as many other neurological problems. For these reasons, talk to a medical professional about aspartic acid supplements before taking them.

Deficiency is very rare since the body makes it, but is still likely to occur especially in individuals who are on low protein diets. People who are not consuming enough food products rich in protein may not get enough aspartic acid in their diet. People included in these groups at risk of aspartic acid deficiency ought to talk to a medical practitioner regarding aspartic acid supplementation before using them. As with anything else, excessive doses of vitamins, minerals or other nutrients cannot cure illnesses and in fact can be very dangerous and produce toxic side effects and interfere with medicine you are taking. Always be sure to consult your doctor just to be on the safe side before taking any type of amino acid supplement.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

Taste, solubility, and suggested preparation of L-Aspartic Acid

This product dissolves quickly in hot water or somewhat slowly in cold water and has a slightly sour but agreeable taste. L-Aspartic Acid has such a mildly sour taste that few people have trouble taking this pure bulk powder dissolved in hot or cold water. Just mix your usual dose with hot water, stir until it is completely dissolved, and then cool with ice and drink, or add the cooled solution to citrus juice and drink.

L-Aspartic Acid is used in the following Proprietary Formulas

Artificial sweeteners (Nutrasweet, Equal, Canderel etc), Mega-Pro Amino 2200, Twinlab Brewers Yeast, All The Whey Whey Protein Concentrate, Twinlab Nitric Fuel, Metabolic Diet Power Drink, KAL Amino Acid Complex 1000, Muscle Gauge Nutrition Recovery 911, Next Generation Labs Finotrenbolone

References & Further Research

Effect of Aspartame and Aspartate Loading upon Plasma and Erythrocyte Free Amino Acid Levels in Normal Adult Volunteer
Aspartame is a dipeptide with a sweeting potential 180 to 200 times that of sucrose. Questions have been raised about potential toxic effects of its constituent amino acids, aspartate and phenylalanine when the compound is ingested in large amounts. In 12 normal subjects after administration of either Aspartame (34 mg/kg) or equimolar quantities of aspartate (13 mg/kg), no changes in either plasma or erythrocyte aspartate levels were noted at any time after either Aspartame or aspartate ingestion, meaning its constituent amino acids have shown no toxic effects.

In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery
Glucocorticoids remain one of the mainstays of therapy for acute attacks of inflammatory bowel disease despite systemic side effects that limit their use. Prodrugs that selectively deliver glucocorticoids to the colon may lower the required dose and side effects. Because enzymes of gut microflora are able to cleave certain peptide and ester bonds, the ability of an ester prodrug consisting of dexamethasone (DX) as model drug and poly(L-aspartic acid) as drug carrier was investigated to selectively release the drug in the large intestine. Results showed this conjugate should both increase efficacy and reduce toxicity to some extent.

L-Aspartic Acid for International Customers

We have the most economical shipping costs & labeling practices for International orders. You can see our shipping costs here. Also, please note, that anything in a 1.5kg package can be shipped within a single flat rate envelope, however our shopping cart mistakenly displays 2 envelopes. Go ahead and ship the order, and you will notice that it only charges you the cost of 1 anyway. Look at the shipping costs tab above to see for yourself how you can calculate these charges.

Buying L-Aspartic Acid Bulk or Wholesale

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