PureBulk

Supplement Facts

Note Do not confuse this product with magnesium gluconate. They are NOT the same.

Caution: Because of the extremely small serving size for this product and the potential for toxicity of overconsumption, please do not purchase manganese gluconate unless you are a compounding pharmacist or other health practice professional. We request that you contact us via email at store@purebulk.com prior to purchasing this product to let us know why you are qualified to purchase, handle and measure this product safely. Please observe extreme caution when measuring and handling manganese gluconate!

What is Manganese Gluconate?

Manganese gluconate is a salt of manganese and gluconic acid that supports energy production, thyroid function and bone development in the body.

Manganese is an essential trace mineral necessary in all life forms. The primary function of manganese is to work as a coenzyme in a number of metabolic processes. Manganese activates enzyme systems involved in protein and energy metabolism and is involved in connective tissue and bone formation, insulin action and cholesterol synthesis.

Manganese is also vital in the biosynthesis of collagen (Wikipedia) as it helps activate key enzymes in collagen formation. It is a component of manganese superoxide dismutase (MnSOD) (Wikipedia), the principal antioxidant enzyme of mitochondria and the principal constituent of the mitochondrial oxidant defense system. Antioxidants such as MnSOD offer protection from the damage free radical molecules can cause to cell membranes in the body.

This mineral also helps facilitate proper mineral transport and absorption.

For athletes on high-protein diets, the supplement is popular because excess protein can deplete minerals, including manganese.

Good natural sources of manganese include avocados, seaweed, tea, raisins, spinach, broccoli, oranges, beans, blueberries, egg yolks, dried peas and green leafy vegetables. Many herbs are also rich in manganese, which include alfalfa, burdock root, chamomile, dandelion, fennel seed, fenugreek, ginseng, hops, horsetail, lemongrass, parsley, peppermint, wild yam and raspberry.

Health Benefits of Manganese Gluconate

Manganese is an essential trace mineral needed in small amounts to synthesize enzymes required for the metabolism of proteins and fat. It also boosts the immune system, helps maintain blood sugar balance and is directly involved in the production of cellular energy.

This mineral triggers one or more enzymes in fatty acid synthesis. Manganese also stimulates and triggers the enzymes responsible for DNA and RNA production, participates directly in the photosynthetic creation of oxygen from water and acts as a catalyst and cofactor in many enzymatic processes involved in the synthesis of fatty acids and cholesterol.

It aids in the formation of connective tissue, bones, blood-clotting factors and sex hormones and plays a role in fat and carbohydrate metabolism and calcium absorption.

Manganese improves the body’s ability to absorb and process vitamin B1 (thiamin) and vitamin E, and works synergistically with all B-complex vitamins.

Purity and Concentration of Manganese Gluconate

This pharmaceutical-grade manganese gluconate is a light pink powder product. Each molecule of manganese gluconate contains approximately 11% elemental manganese by weight. This product contains no fillers, taste additives or anti-caking agents.

Suggested Use of Manganese Gluconate

The suggested serving size for manganese gluconate is 100 milligrams daily. The FDA recommends a daily intake (DV) of 2 milligrams (mg) per day of elemental manganese. Elemental refers to the amount of manganese in a compound. As this supplement is 11% elemental manganese, taking 100 milligrams of manganese gluconate powder will yield 11 milligrams elemental manganese, or 550% of the daily value for adults.

Manganese gluconate can potentially be toxic, so extreme care should be exercised when measuring this product for individual use and dietary supplementation. We do not recommend using volumetric measuring techniques because, apart from the quantitative skills required, measuring spoon methods for determining milligram equivalents can be highly inaccurate. DO NOT ATTEMPT TO MEASURE THIS PRODUCT USING MEASURING SPOONS OF ANY KIND!

The only safe way to determine such a small amount of this product will be using an accurate milligram weight scale. We suggest using an accurate 1/100th gram weight scale such as the model 100AX that we sell on our website: 1/100th gram (milligram) weight scales.

Potential Side Effects of Manganese Gluconate

Manganese gluconate is safe at suggested serving sizes. If taken in excess amounts manganese can become toxic, just like other minerals. Toxicity can result in manganism, a form of Parkinson’s disease-type neurodegeneration. Manganese supplements are contraindicated in those with liver failure. Those with chronic liver disease or iron-deficiency anemia should not use this product. It is not recommended for women who are pregnant or nursing.

Bioavailability, Mixing and Solubility of Manganese Gluconate

Manganese gluconate is a pinkish powder that is water soluble, but insoluble in benzene and alcohol. Manganese supplements should be taken on an empty stomach and should not be combined with iron, calcium, copper or zinc, which reduce the absorption of manganese.

How should I store it?

You will receive this powder in a resealable bag. Store it in a cool, dry, dark location. Reseal tightly between uses.

References & Further Research

Wikipedia: Manganese University of Maryland Medical Center: Manganese

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.