PureBulk

Supplement Facts

Purebulk Vitamin E products:

Vitamin E (DL) Oil-ZMC, Vitamin E Acid Succinate, Vitamin E Clear 230IU, Vitamin E Oil 1300 IU, Vitamin E Powder 700IU, Mixed Tocopherols 1040 IU.

What are Mixed Tocopherols 1040 IU/g?

Purebulk's mixed tocopherols are comprised of naturally occuring stereoisomers of Vitamin E, the most effective fat-soluble antioxidant (Wikipedia) in the body. They provide protection from free radical molecules that can damage cell membranes.

Vitamin E is actually a collective term for a group of compounds called tocopherols and tocotrienols. Each form has its own biological activity - the measure of potency or functional use in the body.

Naturally occurring vitamin E exists in eight chemical forms (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol) that have varying levels of biological activity. This product contains the gamma, delta, alpha and some beta tocopherols.

Alpha-tocopherol is the preferred form of vitamin E for absorption and accumulation. It is the most active form of vitamin E in the body. Of the eight naturally occurring forms of vitamin E, it appears that only naturally occurring alpha-tocopherol (commonly known as d-alpha-tocopherol) is maintained in the human blood circulation. Synthetic alpha-tocopherol is commonly known as dl-alpha-tocopherol. There are indications that the mixed tocopherols may enhance the antioxidant ability of alpha tocopherol.

In terms of absorption and retention in the human body, this natural form of vitamin E is clearly superior over the other analogs. The name "tocopherol" was coined from the Greek words for childbirth (tos), to bring forth (phero), and the chemical designation for an alcohol (ol).

Vitamin E is largely used in skin creams and lotions for its role in stimulating skin healing and minimizing scarring after injuries such as burns. As one of the many nutrients that have protective properties, Vitamin E’s main function is to maintain the integrity of the body's intracellular membrane by shielding its physical stability and providing a defense line against tissue damage brought about by oxidation.

The vitamin is absorbed from the intestines, along with fat and bile salts, first into the lymph and then into the blood, which carries it to the liver to be used or stored. As a co-enzyme in cellular membranes, Vitamin E acts as a scavenger for free radicals that are destructive to the membrane and internal cellular components.

In supplements, vitamin E is usually sold as alpha-tocopheryl acetate, a form that protects its ability to function as an antioxidant.

Vitamin E is found naturally in some foods, is added to others and is also available as a dietary supplement. Antioxidants shield cells from the negative effects of free radicals, molecules that contain an unshared electron which can damage cells.

These unshared electrons are highly energetic and rapidly react with oxygen-yielding reactive oxygen species (ROS). The body forms ROS internally when it transforms food to energy, and antioxidants protect cells from the adverse effects of ROS. ROS are part of signaling mechanisms among cells. Environmental exposures, such as cigarette smoke, air pollution, and ultraviolet radiation from the sun also expose the body to free radicals.

This antioxidant limits and hinders the production of ROS synthesized when fat undergoes oxidation. Scientists are still studying how vitamin E and other mechanisms, by limiting free-radical production, might help prevent or delay the onset of chronic diseases involved with free radicals.

In addition to its activities as an antioxidant, vitamin E is linked to immune function, cell signaling, regulation of gene expression and other metabolic processes.

Health Benefits of Mixed Tocopherols

The most critical role of vitamin E is in maintaining the integrity of the body's intracellular membrane and providing a defense line against tissue damage resulting from oxidation.

Vitamin E has protective attributes because it can reduce oxidation of lipid membranes and unsaturated fatty acids and prevent the breakdown of other nutrients caused by oxygen.

As an antioxidant that prevents free radical damage in cell membranes, vitamin E helps to stabilize cells and protect the tissues of the skin, eyes, liver, breast and testes, which are more sensitive to oxidation.

The protective, nutritional antioxidant function of vitamin E also works synergistically with other antioxidants, such as vitamin C, beta-carotene, glutathione (L-cysteine), and selenium.

Vitamin E keeps arteries flexible and elastic to allow blood to flow freely and helps prevent arteries from clogging.

By supporting the immune system, antioxidants such as vitamin E can also help protect against oxidative damage to DNA.

Purity and Concentration of Mixed Tocopherols

Derived form all natural vegetable oils, Purebulk's Mixed Tocopherols contain no fillers, taste additives or anti-caking agents. The product is assayed to contain at least vitamin E as mixed tocopherols. Of these total tocopherols, 60% are in the form of D-gamma tocopherol, 28% in the form of D-delta tocopherol, 8% D-alpha tocopherol and 1% D-beta-tocopherol.

Suggested Use of Mixed Tocopherols

As a dietary supplement, take 1/8 tsp, preferably with a meal (or as directed by physician). Individual needs may vary. You can see the full bulk density/volumetric conversion chart for Vitamin E here.

This product is assayed to contain 1040 IU/gram of natural vitamin E. IU refers to International Unit: a standard unit of measurement for vitamin content. The U.S. Food and Drug Administration (FDA) recommends a Daily Value (DV) of 30 IU for adults and children four or more years of age. A serving of 1/8 teaspoon will provide 1963% of the Daily Value or 589 IU (international units) of vitamin E.

Potential Side Effects of Mixed Tocopherols

The health risk of too much vitamin E is low.

However, persons taking blood thinners (anticoagulants) should take not more than 800 IU a day of Vitamin E as it may interfere with the body's ability to clot blood.

Bioavailability, Mixing and Solubility of Vitamin E

Non-water-soluble or fat-soluble supplements such as Vitamin E should be taken at meal time with fatty foods. Since vitamin E is fat soluble, it need not be taken daily.

How should I store it?

Store in a cool, dry area protected from light. Reseal after each use. Refrigeration is not required, but be sure to keep away from heat or sun.

References & Further Research

University of Maryland Medical Center: Vitamin E

Linus Pauling Institute, Micronutrient Information Center: Vitamin E

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

The information at Purebulk.com is NOT a substitute for medical advice. ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell all your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than conventional medicines. The standards for supplements are found in the Dietary Supplement Health and Education Act (DSHEA), a federal law that defines dietary supplements and sets product-label­ing standards and health claim limits. To learn more about DSHEA, visit the FDA Web site.