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Alpha Lipoic Acid (R-ALA) (Thioctic Acid)

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Alpha Lipoic Acid (R-ALA) (Thioctic Acid)
From: $14.00

Availability: In stock

R-alpha lipoic acid (also known as R-ALA or thioctic acid) is a sulfur-containing organic acid powerful antioxidant, and an essential component of aerobic metabolism.

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NOTICE!   R-Alpha Lipoic Acid has a relatively low melting temperature of approximately 110° F (38° C). During the summer months it is not uncommon that temperatures encountered during shipping will exceed this melting temperature and your R-Alpha Lipoic Acid will melt during transit, forming a clumpy or semi-solid mass upon receipt. Melting does not effect the nutritional benefits, bioavailability or potency of R-Alpha Lipoic Acid. After melting and then cooling the re-solidified R-ALA will appear to be a semi-clumpy powder or rubbery solid yellow mass. Unfortunately, once melted it is not practical to restore R-ALA back to a free flowing powder, but it can still be used as a fully potent dietary supplement. If you are concerned about the possibility of melting during transit please DO NOT ORDER this product during the summer months. Please wait until cooler weather prevails in your area before ordering.

R-alpha lipoic acid (also known as R-ALA or thioctic acid) is a sulfur-containing organic acid powerful antioxidant, and an essential component of aerobic metabolism.

Alpha lipoic acid exists in two stereoisomers, the biologically active R-ALA, in addition to S-ALA, which is not produced in the human body. R-alpha lipoic acid is produced synthetically, and chemical manufacturing processes yield both the R- and S- isomers. The pure R- form is more costly to refine, as a result.

Supplementation of R-alpha lipoic acid may help support a healthy metabolism.

Alpha lipoic acid has an unpleasant chemical burning taste. Capsules are generally preferred.

*NOTE: These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.

Supplement Facts
Supplement Facts
Supplement facts displayed on this page may vary from the package you receive. (The serving size "volume" may vary depending on the density of each batch.)
Refrigerate upon arrival!
Alpha Lipoic Acid Supplement Facts
What is the difference between: Alpha Lipoic Acid (R-ALA) and Alpha Lipoic Acid (RS-ALA)?
R = Rectus (Latin for Right)
S = Sinister (Latin for Left)
R and S are the stereoisomers for this molecule, alpha lipoic acid.

When you see both RS before a given molecule name it means that it is a racemic mixture of both the Rectus and Sinister stereo isomers and in this case both are also enantiomers.

A racemic mixture is typically 50% of each of two stereo isomers below

The biggest difference between the R and the RS enantiomers of Alpha Lipoic acid is the cost. The R is about 10 times more expensive than the RS. Another consideration you might relate to is the fact that there is about 100 times more RS than R manufactured and consumed nutritionally.

Why would only 1% of alpha Lipoic Acid manufactured be the R? Because its cheaper than the RS.

Is there a difference between the R and the RS such that one would be better nutritionally than the other? Yes. The R is about twice as effective than the RS because the S is basically useless.

Is there a problem with the S such that having it with the R would justify paying 10 times more for the R versus the RS? Maybe. It depends upon what research you read and what you think of the research. Given that almost all the research supporting one camp or the other is theoretical there doesn't seem to be a whole lot of facts supporting either opinion.

My belief is that deciding which to take would depend upon your choice in the matter, and how much money you have to spend. The more money you have to spend on Alpha Lipoic acid the more you would probably want to purchase the R versus the RS. The less money you have to burn on Alpha Lipoic acid the more likely you would choose the RS. Unquestionably, the greatest bang for your buck is with the RS as 99% of Alpha Lipoic acid consuming public would likely concur.
Is this item vegetarian? What is the shelf life of this item?
The R-ALA is both Vegan and Vegetarian, the shelf life is a little over 3 years, but we suggest retesting after 3 years.

*NOTE: These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.

Do you have a question about this product? Fill out the box below and your question may appear on this page as an FAQ or we will email you the answer if not an FAQ!

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Customer Reviews 3 item(s)

Research on R-ALA
PureBulk provides a great service with so many excellent supplements. Regarding ALA, however, research shows that the R-lipoic form is not at all stable and is frequently very poorly absorbed. The truly excellent supplement on the market is sodium-R-lipoate, or the sodium salt of R-lipoic acid.

I strongly encourage you to carry this supplement. My own experience as well as the published research shows that it is better to take the common racemic (mixed isomers) form, or regular ALA than it is to take R-ALA. Please folks, consider adding the stable and far superior sodium-R-lipoate to your product line. Once you try it, you will never want to bother with any other form.
Review by Paul / (Posted on 11/19/2015)
Very pleased.
The first few days of taking this I just combined it in with a drink. Did okay even though I 'sensed' the chemical hotness of it.

BUT! now I am putting it into capsules because one day a large-ish particle (it does stick together) must have gotten into a laryngeal fold and my eyes teared and teared and throat burned for a long time, LOL... My fault... we are fore-warned about this.

Nevertheless, I am still quite pleased with the quality and results that I am getting. We are taking it with ALCAR too.
Review by Nancy / (Posted on 4/18/2015)
By happy chance
I ordered l-carnitine by mistake believing it to be something else but learned a synergetic partner than has great use for cognitive increase if taken for a few weeks. This may be only limited to my personal experience but Alpha Lipoic Acid (R-ALA) works great in conjunction with L-Carnitine. Though usually I shy from indorsing I got tremendous results on lumosity.com scores blowing them away consistently. I believe this may help others. I haven't take for more of this combination or any other supplements beyond 5 months, usually shorter and don't know long term side effects.
Review by Clarence / (Posted on 4/18/2015)

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