PureBulk

Note:

This product is concentrated Cyanocobalamin. However, we do offer a 01% Cyanocobalamin and 99% Mannitol blended product as well.

Because of the extremely small recommended serving size for this product, and the potential for TOXICITY reactions from excess use, do not purchase this product unless you are a compounding pharmacist or other health practice professional. We request that you contact us via email at store@purebulk.com prior to purchasing this product to let us know why you are qualified to purchase, handle and dose this product safely. Please observe extreme caution when measuring and handling this product.

What is Cyanocobalamin?

Vitamin B12, also known as cyanocobalamin or cobalamin, is a water-soluble compound stored in the liver that works with other B vitamins to turn food into energy. It is considered the most potent vitamin in the body.

Unlike other water-soluble nutrients, high levels of vitamin B12 are stored in the liver, kidney and other body tissues. Vitamin B12 is a general term used to refer to a group of cobalt-containing compounds called corrinoids. Vitamin B12 is also known as cobalamin because a major constituent is the metal cobalt.

The major cobalamins include cyanocobalamin, hydroxocobalamin and the coenzyme analogs of vitamin B12, methylcobalamin and 5-deoxyadenosylcobalamin (adenosylcobalamin).

Cyanocobalamin is the common form of the vitamin used as an additive in the fortification of foods and in nutritional supplements. Vitamin B12 is bound to proteins in food, and hydrochloric acid in the stomach releases B12 from food proteins during digestion.

Cyanocobalamin is combined in the body with a substance called gastric intrinsic factor (IF), which is then absorbed by the intestinal tract. Intrinsic factor is secreted by the stomach lining, tightly binding vitamin B12 to help it pass through the intestinal lining and into the blood.

Any abnormal production or shortage of this intrinsic factor can result in Vitamin B12 deficiency.

Vitamin B12 is important for normal nerve cell activity, DNA replication and production of S-adenosyl-L-methionine (SAM).

Vitamin B12 also works intimately with vitamin B9 (folate) to regulate the formation of red blood cells, helping iron function better in the body and preventing anemia. Vitamin B12 is needed for the action of certain enzymes within calls that control fat and amino acid and carbohydrate metabolism. Vitamin B12 and folate are essential in the synthesis of DNA and RNA, the genetic material in the body.

Vitamin B12 is found naturally in food sources (primarily animal products) in protein-bound forms. Excellent dietary sources of vitamin B12 include liver, tuna, cottage cheese, yogurt and eggs. The only reliable unfortified sources of vitamin B12 are meat, dairy products and eggs.

Since Vitamin B12 is bound to the protein in many of these foods, it must be released during digestion. Persons with low levels of gastric acid may be unable to properly process these sources. Most standard multivitamin supplements are formulated with the recommended daily allowance of vitamin B12.

Benefits of Cyanocobalamin

Vitamin B12's main functions are in the formation of red blood cells and the maintenance of a healthy nervous system. Vitamin B12 helps maintain nerve cells and aids production of DNA and RNA, the body's genetic material.

Nerves are surrounded by an insulating fatty sheath comprised of a complex protein called myelin. B12 plays a vital role in the metabolism of fatty acids essential for the maintenance of myelin. Prolonged B12 deficiency can lead to nerve degeneration and irreversible neurological damage.

Vitamin B9 (folate) and vitamin B12 are critical to a process that clears homocysteine from the blood. Elevated plasma homocysteine concentrations are being studied as a risk factor for vascular problems.

Purity and Concentration of Cyanocobalamin

This cyanocobalamin powder contains no fillers, taste additives or anti-caking agents. You will receive a resealable bag of this powder. Store in a cool, dry area protected from light. Reseal after each use.

Potential Side Effects of Cyanocobalamin

Vitamin B12 is considered safe and nontoxic in suggested serving sizes. However, cyanocobalamin can be toxic if taken in excess! This is a concentrated product; extreme caution is required when measuring and handling this product.

Because of the extremely small serving size for this product and the potential for toxicity please do not purchase this product unless you are a compounding pharmacist or other health practice professional. Please observe extreme caution when measuring and handling this product. We request that you contact us via email at store@purebulk.com prior to purchasing this product to let us know why you are qualified to purchase, handle and measure this product safely.

DO NOT ATTEMPT TO MEASURE THIS PRODUCT USING MEASURING SPOONS OF ANY KIND! An accurate milligram weight scale should be used. (Purebulk offers several scales. See our product listings.)

What is vitamin B12 deficiency?

Vitamin B12 deficiency occurs when there is an abnormally low level of the vitamin absorbed in the body. It can be a factor in a variety of different health conditions and disorders. B12 deficiency inhibits the body’s ability to produce blood, increases blood cell destruction and is harmful to the nervous system. Characteristic signs of B12 deficiency include fatigue, weakness, nausea, constipation, flatulence, loss of appetite and weight loss. Symptoms of severe vitamin B12 deficiency (regardless of the cause) may include a burning feeling on the tongue, fatigue, weakness, loss of appetite, intermittent constipation and diarrhea, abdominal pain, weight loss, menstrual problems, psychological symptoms and nervous system problems such as numbness and tingling in the feet and hands.

Vitamin B12 is not usually present in plant food sources, and it is likely that a vegetarian will not consume enough of this vitamin in their diet. Cobalamin levels decline with age.

References & Further Research

National Institutes of Health, Office of Dietary Supplements: Vitamin B12

University of Maryland Medical Center: Vitamin B12 Overview

Linus Pauling Institute: Vitamin B12

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.