{"title":"Sales \u0026 Specials","description":"","products":[{"product_id":"niacin-vitamin-b3-immediate-release","title":"Niacin (Vitamin B3) Immediate Release","description":"\n\u003cdiv class=\"row supplement product-information\"\u003e\n  \u003ch4 class=\"nm uppercase\"\u003eSupplement Facts \u0026amp; Directions\u003c\/h4\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003c!--           --\u003e\n    \u003c!-- BAGS PANEL START --\u003e\n    \u003c!--           --\u003e\n    \u003cdiv class=\"facts suppfacts supplement-powder\"\u003e\n      \u003ch2\u003eSupplement Facts\u003c\/h2\u003e\n      \u003cspan\u003e Serving Size: 500 milligrams\u003c\/span\u003e \u003cbr\u003e\n      \u003cspan\u003eServings Per Container: Varies\u003c\/span\u003e\n      \u003chr class=\"topHr\"\u003e\n      \u003ctable\u003e\n        \u003cthead\u003e\n          \u003ctr\u003e\n            \u003cth\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/th\u003e\n            \u003cth\u003e\u003cstrong class=\"go-right\"\u003e% Daily Value*\u003c\/strong\u003e\u003c\/th\u003e\n          \u003c\/tr\u003e\n        \u003c\/thead\u003e\n        \u003ctbody\u003e\n          \u003ctr\u003e\n            \u003ctd\u003eNiacin 500 mg\u003c\/td\u003e\n            \u003ctd class=\"go-right\"\u003e2500%\u003c\/td\u003e\n          \u003c\/tr\u003e\n        \u003c\/tbody\u003e\n      \u003c\/table\u003e\n      \u003chr class=\"bottomHr\"\u003e\n      \u003cdiv class=\"factsNotes\"\u003e\n        \u003cp\u003e\n          * Percent Daily Values are based on a 2,000 calorie diet.\u003cbr\u003e† Daily\n          Value Not Established \u003cbr\u003e‡ These supplement facts may vary from the\n          product you receive. Please call for exact numbers.\n        \u003c\/p\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n    \u003c!--           --\u003e\n    \u003c!-- VEGCAPS PANEL START --\u003e\n    \u003c!--           --\u003e\n    \u003cdiv class=\"facts suppfacts supplement-vegcaps\" style=\"display: none\"\u003e\n      \u003ch2\u003eSupplement Facts\u003c\/h2\u003e\n      \u003cspan\u003e Serving Size: 1 Capsule\u003c\/span\u003e \u003cbr\u003e\n      \u003cspan\u003eServings Per Container: Varies\u003c\/span\u003e\n      \u003chr class=\"topHr\"\u003e\n      \u003ctable\u003e\n        \u003cthead\u003e\n          \u003ctr\u003e\n            \u003cth\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/th\u003e\n            \u003cth\u003e\u003cstrong class=\"go-right\"\u003e% Daily Value*\u003c\/strong\u003e\u003c\/th\u003e\n          \u003c\/tr\u003e\n        \u003c\/thead\u003e\n        \u003ctbody\u003e\n          \u003ctr\u003e\n            \u003ctd\u003eNiacin 500 mg\u003c\/td\u003e\n            \u003ctd class=\"go-right\"\u003e2500%\u003c\/td\u003e\n          \u003c\/tr\u003e\n        \u003c\/tbody\u003e\n      \u003c\/table\u003e\n      \u003chr class=\"bottomHr\"\u003e\n      \u003cdiv class=\"factsNotes\"\u003e\n        \u003cp\u003e\n          * Percent Daily Values are based on a 2,000 calorie diet.\u003cbr\u003e† Daily\n          Value Not Established \u003cbr\u003e‡ These supplement facts may vary from the\n          product you receive. Please call for exact numbers.\n        \u003c\/p\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n    \u003c!--           --\u003e\n    \u003c!-- GELCAPS PANEL START --\u003e\n    \u003c!--           --\u003e\n    \u003cdiv class=\"facts suppfacts supplement-gelcaps\" style=\"display: none\"\u003e\n      \u003ch2\u003eSupplement Facts\u003c\/h2\u003e\n      \u003cspan\u003e Serving Size: 1 Capsule\u003c\/span\u003e \u003cbr\u003e\n      \u003cspan\u003eServings Per Container: Varies\u003c\/span\u003e\n      \u003chr class=\"topHr\"\u003e\n      \u003ctable\u003e\n        \u003cthead\u003e\n          \u003ctr\u003e\n            \u003cth\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/th\u003e\n            \u003cth\u003e\u003cstrong class=\"go-right\"\u003e% Daily Value*\u003c\/strong\u003e\u003c\/th\u003e\n          \u003c\/tr\u003e\n        \u003c\/thead\u003e\n        \u003ctbody\u003e\n          \u003ctr\u003e\n            \u003ctd\u003eNiacin 500 mg\u003c\/td\u003e\n            \u003ctd class=\"go-right\"\u003e2500%\u003c\/td\u003e\n          \u003c\/tr\u003e\n        \u003c\/tbody\u003e\n      \u003c\/table\u003e\n      \u003chr class=\"bottomHr\"\u003e\n      \u003cdiv class=\"factsNotes\"\u003e\n        \u003cp\u003e\n          * Percent Daily Values are based on a 2,000 calorie diet.\u003cbr\u003e† Daily\n          Value Not Established \u003cbr\u003e‡ These supplement facts may vary from the\n          product you receive. Please call for exact numbers.\n        \u003c\/p\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n  \u003c!--end supp facts--\u003e\n  \u003cdiv class=\"column whole medium-half np product-information--description\"\u003e\n    \u003c!--           --\u003e\n    \u003c!-- BAGS INFO START --\u003e\n    \u003c!--           --\u003e\n    \u003cdiv class=\"suppfacts supplement-powder\"\u003e\n      \u003cp\u003e\u003cspan class=\"directionsSpan\"\u003eOther Ingredients: \u003c\/span\u003eNone\u003c\/p\u003e\n      \u003cp style=\"display: none\"\u003e\u003cspan class=\"directionsSpan\"\u003eContains:\u003c\/span\u003e\u003c\/p\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsSpan\"\u003eFree of: \u003c\/span\u003eAdded Sugar, Soy, Dairy,\n        Yeast, Gluten, Corn \u0026amp; Additives.\n      \u003c\/p\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsSpan\"\u003eDirections: \u003c\/span\u003eAs a dietary supplement,\n        take 250 to 500 mg (3\/16 tsp) daily with meals or as directed by a\n        physician. An accurate gram weight scale is recommended.\n      \u003c\/p\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsWarning\"\u003eWarning: \u003c\/span\u003eIf you are pregnant,\n        nursing, taking any medications, or have any medical conditions consult\n        your physician before use. Niacin may cause a temporary flushing\n        reaction when serving more than 100 mg. Keep out of reach of children.\n      \u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003c!--           --\u003e\n    \u003c!-- VEGCAPS INFO START --\u003e\n    \u003c!--           --\u003e\n    \u003cdiv class=\"suppfacts supplement-vegcaps\" style=\"display: none\"\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsSpan\"\u003eOther Ingredients: \u003c\/span\u003eCellulose Capsule\n      \u003c\/p\u003e\n      \u003cp style=\"display: none\"\u003e\u003cspan class=\"directionsSpan\"\u003eContains:\u003c\/span\u003e\u003c\/p\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsSpan\"\u003eFree of: \u003c\/span\u003eAdded Sugar, Soy, Dairy,\n        Yeast, Gluten, Corn \u0026amp; Additives.\n      \u003c\/p\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsSpan\"\u003eDirections: \u003c\/span\u003eAs a dietary supplement,\n        take one capsule daily with a meal or as directed by a physician.\n      \u003c\/p\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsWarning\"\u003eWarning: \u003c\/span\u003eIf you are pregnant,\n        nursing, taking any medications, or have any medical conditions consult\n        your physician before use. Niacin may cause a temporary flushing\n        reaction when serving more than 100 mg. Keep out of reach of children.\n      \u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003c!--           --\u003e\n    \u003c!-- GELCAPS INFO START --\u003e\n    \u003c!--           --\u003e\n    \u003cdiv class=\"suppfacts supplement-gelcaps\" style=\"display: none\"\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsSpan\"\u003eOther Ingredients: \u003c\/span\u003eGelatin Capsule\n        (Bovine Source)\n      \u003c\/p\u003e\n      \u003cp style=\"display: none\"\u003e\u003cspan class=\"directionsSpan\"\u003eContains:\u003c\/span\u003e\u003c\/p\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsSpan\"\u003eFree of: \u003c\/span\u003eAdded Sugar, Soy, Dairy,\n        Yeast, Gluten, Corn \u0026amp; Additives.\n      \u003c\/p\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsSpan\"\u003eDirections: \u003c\/span\u003eAs a dietary supplement,\n        take one capsule daily with a meal or as directed by a physician.\n      \u003c\/p\u003e\n      \u003cp\u003e\n        \u003cspan class=\"directionsWarning\"\u003eWarning: \u003c\/span\u003eIf you are pregnant,\n        nursing, taking any medications, or have any medical conditions consult\n        your physician before use. Niacin may cause a temporary flushing\n        reaction when serving more than 100 mg. Keep out of reach of children.\n      \u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- split --\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003ch4 class=\"nm uppercase\"\u003e\n      \u003ca style=\"color: #7d7d7d !important\" name=\"ProductDetails\"\u003e\u003c\/a\u003eProduct\n      Details\n    \u003c\/h4\u003e\n    \u003cp\u003e\n      Niacin, also called nicotinic acid or Vitamin B3, is a water-soluble\n      member of the B complex family. Niacin is one of the most stable B\n      vitamins, as it is resistant to the effects of heat, light, air, acid, and\n      alkali. Niacin is critical for synthesizing coenzymes that play a role in\n      hundreds of bodily functions. However, its primary role is to obtain\n      usable energy from food by supporting the enzymes responsible for cellular\n      metabolism.\n    \u003c\/p\u003e\n    \u003cp\u003e\n      PureBulk's Niacin is the immediate release form of this vitamin, not a\n      timed or slow release.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--split--\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003ch2\u003ePotential Benefits of Niacin Supplements\u003c\/h2\u003e\n    \u003cp\u003e\n      Niacin is critical for transforming food into energy within the body. It\n      is a precursor for the nucleotide nicotinamide adenine dinucleotide (NAD).\n      NAD exists in an oxide and reduced form, which comprise a REDOX\n      (oxidation-reduction) pair. A NAD REDOX reaction occurs when one NAD\n      molecule oxidizes to transfer an electron to another NAD molecule. This\n      electron transfer is a significant source of cellular energy.\n    \u003c\/p\u003e\n    \u003ch4\u003eNiacin as an Antioxidant\u003c\/h4\u003e\n    \u003cp\u003e\n      Niacin supplements exert antioxidant effects as well. Niacin is a cofactor\n      for many antioxidant enzymes and energizes these enzymes through REDOX\n      reactions. The body needs an adequate supply of NAD to protect and repair\n      cells damaged by oxidative stress.\n    \u003c\/p\u003e\n    \u003ch4\u003eNiacin for Cholesterol\u003c\/h4\u003e\n    \u003cp\u003e\n      Niacin influences several lipids found in the blood, including HDL\n      cholesterol, LDL cholesterol, and triglycerides. Niacin supplements may be\n      able to help balance the blood levels of these lipids. Improving blood fat\n      levels also supports heart health. Niacin offers additional support for\n      heart health by releasing prostaglandins. Prostaglandins reduce\n      inflammation and help widen blood vessels, which improves blood flow.\n    \u003c\/p\u003e\n    \u003ch4\u003eNiacin for Skin\u003c\/h4\u003e\n    \u003cp\u003e\n      Niacin’s anti-inflammatory properties promote skin health. It also helps\n      protect skin from sun damage. Niacin may improve hyperpigmentation on the\n      skin by acting as a lightning agent.\n    \u003c\/p\u003e\n    \u003ch2\u003ePotential Niacin Side Effects\u003c\/h2\u003e\n    \u003cp\u003e\n      Niacin may increase blood sugar levels. Individuals that have problems\n      regulating their blood sugar should speak with their physician before\n      taking niacin supplements. High doses of niacin supplements may also cause\n      the skin to flush.\n    \u003c\/p\u003e\n    \u003ch2\u003eWhat is the Niacin Flush?\u003c\/h2\u003e\n    \u003cp\u003e\n      Large amounts of niacin supplements can cause the skin to turn red and\n      grow warm. Niacin supplements may widen blood vessels and increase blood\n      flow, which can lead to a flushed appearance. This flush isn’t harmful,\n      but some individuals experience headaches during a niacin flush.\n    \u003c\/p\u003e\n    \u003ch2\u003eNiacin vs Niacinamide\u003c\/h2\u003e\n    \u003cp\u003e\n      PureBulk offers two forms of Vitamin B3 supplements: niacin and\n      \u003ca href=\"https:\/\/purebulk.com\/products\/niacinamide-powder-vitamin-b3\"\u003eniacinamide.\u003c\/a\u003e\n      The chemical difference between the two forms is that niacinamide has an\n      amide group attached to the basic niacin form. Both compounds can convert\n      into the coenzymes NAD+, NADP+, NADH, and NADPH, playing key roles in\n      energy metabolism and anabolism.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--split--\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003ch4\u003eReferences\u003c\/h4\u003e\n    \u003col\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\"\u003ehttps:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26828517\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26828517\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28616955\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/28616955\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27793642\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/27793642\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33404619\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/33404619\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16322797\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16322797\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/bio.libretexts.org\/Bookshelves\/Microbiology\/Book%3A_Microbiology_(Bruslind)\/12%3A_Energetics_and_Redox_Reactions\"\u003ehttps:\/\/bio.libretexts.org\/Bookshelves\/Microbiology\/Book%3A_Microbiology_(Bruslind)\/12%3A_Energetics_and_Redox_Reactions\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18165311\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18165311\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7641178\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7641178\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20725615\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20725615\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25306426\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/25306426\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7657446\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7657446\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12100180\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12100180\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2779993\/\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2779993\/\u003c\/a\u003e\n      \u003c\/li\u003e\n    \u003c\/ol\u003e\n    \u003ch2\u003eTested by Accredited 3rd Party Labs\u003c\/h2\u003e\n    \u003cp\u003e\n      PureBulk's supplements are tested by accredited third party labs in the\n      USA to ensure their identity, purity and potency. To receive a copy of\n      these test results or any other PureBulk supplement please fill out the\n      \u003ca href=\"\/pages\/coa-request\"\u003eCOA request form\u003c\/a\u003e found\n      \u003ca href=\"\/pages\/coa-request\"\u003ehere\u003c\/a\u003e.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n  \u003c!-- end product-information--description --\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"row bottom-shadow product-information\"\u003e\n  \u003cp\u003e\n    \u003cstrong\u003e*NOTE: These statements have not been evaluated by the Food and Drug\n      Administration. This product is not intended to diagnose, treat, cure or\n      prevent any disease.\u003c\/strong\u003e\n  \u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"purebulkinc","offers":[{"title":"Bags \/ 100 grams","offer_id":14279475101745,"sku":"11123","price":4.24,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 250 grams","offer_id":14294913482801,"sku":"11125","price":9.05,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 500 grams","offer_id":14294913515569,"sku":"11126","price":16.37,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 1 kilogram","offer_id":14294913548337,"sku":"11124","price":29.46,"currency_code":"USD","in_stock":true},{"title":"Capsules \/ 120ct 500mg Veg. Caps.","offer_id":45867410653381,"sku":"13048","price":8.09,"currency_code":"USD","in_stock":true},{"title":"Capsules \/ 120ct 500mg Gel. Caps.","offer_id":45867410686149,"sku":"13046","price":8.67,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6379\/6273\/files\/M36736_-_PureBulk.com_3.png?v=1744899870"},{"product_id":"inositol-hexanicotinate","title":"Inositol Hexanicotinate Powder","description":"\u003cdiv class=\"row supplement product-information\"\u003e\n  \u003ch4 class=\"nm uppercase\"\u003eSupplement Facts \u0026amp; Directions\u003c\/h4\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003cdiv class=\"facts suppfacts supplement-powder\"\u003e\n      \u003ch2\u003eSupplement Facts\u003c\/h2\u003e\n      \u003cspan\u003e Serving Size: 500 milligrams\u003c\/span\u003e \u003cbr\u003e \u003cspan\u003eServings Per Container: Varies\u003c\/span\u003e\n      \u003chr class=\"topHr\"\u003e\n      \u003ctable\u003e\n        \u003cthead\u003e\n          \u003ctr\u003e\n            \u003cth\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/th\u003e\n            \u003cth\u003e\u003cstrong class=\"go-right\"\u003e% Daily Value*\u003c\/strong\u003e\u003c\/th\u003e\n          \u003c\/tr\u003e\n        \u003c\/thead\u003e\n        \u003ctbody\u003e\n          \u003ctr\u003e\n            \u003ctd\u003eNiacin (from Inositol Hexanicotinate) 400 mg\u003c\/td\u003e\n            \u003ctd class=\"go-right\"\u003e 2000%\u003c\/td\u003e\n          \u003c\/tr\u003e\n          \u003ctr\u003e\n            \u003ctd\u003eInositol (from Inositol Hexanicotinate) 100 mg\u003c\/td\u003e\n            \u003ctd class=\"go-right\"\u003e †\u003c\/td\u003e\n          \u003c\/tr\u003e\n        \u003c\/tbody\u003e\n      \u003c\/table\u003e\n      \u003chr class=\"bottomHr\"\u003e\n      \u003cdiv class=\"factsNotes\"\u003e\n        \u003cp\u003e* Percent Daily Values are based on a 2,000 calorie diet.\u003cbr\u003e† Daily Value Not Established \u003cbr\u003e‡\n          These supplement facts may vary from the product you receive. Please call for exact numbers.\u003c\/p\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n  \u003c!--end supp facts--\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003cdiv class=\"suppfacts supplement-powder\"\u003e\n      \u003cp\u003e\u003cspan class=\"directionsSpan\"\u003eOther Ingredients: \u003c\/span\u003eNone\u003c\/p\u003e\n      \u003cp style=\"display: none;\"\u003e\u003cspan class=\"directionsSpan\"\u003eContains:\u003c\/span\u003e\u003c\/p\u003e\n      \u003cp\u003e\u003cspan class=\"directionsSpan\"\u003eFree of: \u003c\/span\u003eFree Sugar, Soy, Dairy, Yeast, Gluten, Corn \u0026amp; Additives.\u003c\/p\u003e\n      \u003cp\u003e\u003cspan class=\"directionsSpan\"\u003eDirections: \u003c\/span\u003eAs a dietary supplement, take 500 mg (1\/8 tsp) up to two times\n        daily, preferably with a meal or as directed by a physician.\u003c\/p\u003e\n      \u003cp\u003e\u003cspan class=\"directionsWarning\"\u003eWarning: \u003c\/span\u003eIf you are pregnant, nursing, taking any medications or have\n        any medical condition consult your physician before use. Keep out of reach of children.\u003c\/p\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- split --\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003ch4 class=\"nm uppercase\" id=\"ProductDetails\"\u003e\n      \u003ca name=\"ProductDetails\" style=\"color: #7d7d7d !important\"\u003e\u003c\/a\u003eProduct\n      Details\n    \u003c\/h4\u003e\n\n    \u003ch2\u003eWhat Is Inositol Hexanicotinate?\u003c\/h2\u003e\n    \u003cp\u003e\n      Inositol hexanicotinate, also known as inositol nicotinate, is a\n      nutritional supplement taken as a flush-free niacin (vitamin B3) analog.\n      It is inositol esterified with niacin. Niacin is essential for converting\n      food into useable energy in the body. It also acts as an antioxidant and\n      may support healthy blood fat levels. Inositol, sometimes referred to as\n      vitamin B8, is a water-soluble, fatty lipid needed for the formation and\n      maintenance of healthy cell membranes. The hydrolysis of 1g inositol\n      hexanicotinate breaks down the compound into 0.91g nicotinic acid and\n      0.22g inositol.\n    \u003c\/p\u003e\n\n    \u003ch2\u003eWhat is the Niacin Flush?\u003c\/h2\u003e\n    \u003cp\u003e\n      Niacin is an essential vitamin, but it often produces a \"niacin flush.\" It\n      stimulates prostaglandin D2 production, a lipid that causes blood vessels\n      to dilate. The sudden surge in these lipids also boosts blood flow, thus\n      triggering a flush response. Flushing characteristics include tingling and\n      itching sensations, skin redness or warmth, sweating, shortness of breath,\n      increased heart rate, chills, dizziness, and even fainting.\n    \u003c\/p\u003e\n\n    \u003ch2\u003eInositol Hexanicotinate: Flush-Free Niacin\u003c\/h2\u003e\n    \u003cp\u003e\n      Inositol hexanicotinate provides the benefits of niacin without its\n      characteristic flush. The body metabolizes inositol hexanicotinate slower\n      than niacin, requiring 6-10 hours to reach peak serum levels compared to\n      0.5-1 hour. Nicotinamide is another flush-free niacin compound.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--split--\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003ch2\u003ePotential Niacin Benefits\u003c\/h2\u003e\n    \u003cp\u003e\n      Niacin is a vital, water-soluble form of vitamin B3, also called niacin,\n      nicotinic acid, nicotinamide, and niacinamide. Niacin is one of the most\n      stable water-soluble vitamins, as it resists the effects of heat, light,\n      air, acid, and alkali. The small intestines absorb niacin readily. Small\n      amounts may be kept in the liver, but the body excretes from of the excess\n      through urine. The body can’t produce niacin and relies on dietary\n      sources.\n    \u003c\/p\u003e\n\n    \u003ch4\u003eNiacin for Energy and Antioxidant Activity\u003c\/h4\u003e\n    \u003cp\u003e\n      Vitamin B3 helps to catalyze or speed up the chemical reactions\n      responsible for generating energy in the body, breaking down dietary fats,\n      creating certain hormones, boosting good cholesterol, processing genetic\n      material (DNA), and the growth and maturation of the cells in the body.\n      It’s a precursor to nicotinamide adenine dinucleotide (NAD), a compound\n      essential for several REDOX reactions. One of these reactions transfers\n      electrons to provide energy at the cellular level. It also energizes\n      antioxidant enzymes and provides the NAD molecules that protect against\n      oxidative stress and repair free radical damage.\n    \u003c\/p\u003e\n\n    \u003ch4\u003eNiacin and Blood Fats\u003c\/h4\u003e\n    \u003cp\u003e\n      Niacin exerts several effects on various blood fats. It’s able to increase\n      high-density lipoprotein (HDL) cholesterol (good cholesterol) while\n      decreasing low-density lipoprotein (LDL) cholesterol (bad cholesterol) and\n      triglycerides. It can boost HDL by more than 30% while lowering\n      triglycerides by 25%. More HDL cholesterol also contributes to lower LDL\n      cholesterol, as it helps remove bad cholesterol from the bloodstream.\n    \u003c\/p\u003e\n\n    \u003ch2\u003ePotential Side Effects of Inositol Hexanicotinate\u003c\/h2\u003e\n    \u003cp\u003e\n      Most individuals can take inositol hexanicotinate without experiencing\n      adverse effects. Some individuals may experience gastrointestinal side\n      effects, such as stomach upset, headache, nausea, burping, and hiccups. It\n      can cause liver damage if taken in excessive amounts. Those taking\n      prescription drugs to treat high cholesterol or elevated blood lipid\n      levels should consult the prescribing physician before taking this\n      product. Check with a health care provider before using inositol\n      hexanicotinate if you have a heart condition, diabetes, kidney problems,\n      or liver disease. Do not take inositol hexanicotinate while pregnant or\n      breastfeeding.\n    \u003c\/p\u003e\n\n    \u003ch2\u003ePurity and Concentration of Inositol Hexanicotinate\u003c\/h2\u003e\n    \u003cp\u003e\n      PureBulk’s inositol hexanicotinate powder contains no fillers, additives,\n      or anti-caking agents.\n    \u003c\/p\u003e\n\n    \u003ch2\u003eHow Should I Store It?\u003c\/h2\u003e\n    \u003cp\u003e\n      PureBulk packages inositol hexanicotinate powder in a resealable bag.\n      Store it in a cool, dry area protected from light. Reseal after each use.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--split--\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003ch2\u003eReferences \u0026amp; Further Research\u003c\/h2\u003e\n    \u003cul\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/efsa.onlinelibrary.wiley.com\/doi\/pdf\/10.2903\/j.efsa.2009.949\"\u003ehttps:\/\/efsa.onlinelibrary.wiley.com\/doi\/pdf\/10.2903\/j.efsa.2009.949\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Inositol-niacinate\"\u003ehttps:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Inositol-niacinate\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/164246\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/164246\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\"\u003ehttps:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26828517\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26828517\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/high-blood-cholesterol\/in-depth\/niacin\/art-20046208\"\u003ehttps:\/\/www.mayoclinic.org\/diseases-conditions\/high-blood-cholesterol\/in-depth\/niacin\/art-20046208\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/lpi.oregonstate.edu\/mic\/vitamins\/niacin\"\u003ehttps:\/\/lpi.oregonstate.edu\/mic\/vitamins\/niacin\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\"\u003ehttps:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/B9780123918826000078\"\u003ehttps:\/\/www.sciencedirect.com\/science\/article\/pii\/B9780123918826000078\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.britannica.com\/science\/niacin\"\u003ehttps:\/\/www.britannica.com\/science\/niacin\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28616955\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/28616955\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27793642\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/27793642\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33404619\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/33404619\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16322797\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16322797\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/bio.libretexts.org\/Bookshelves\/Microbiology\/Book%3A_Microbiology_(Bruslind)\/12%3A_Energetics_and_Redox_Reactions\"\u003ehttps:\/\/bio.libretexts.org\/Bookshelves\/Microbiology\/Book%3A_Microbiology_(Bruslind)\/12%3A_Energetics_and_Redox_Reactions\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18165311\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18165311\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7641178\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7641178\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20725615\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20725615\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25306426\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/25306426\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7657446\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7657446\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12100180\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12100180\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2779993\/\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2779993\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22037771\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/22037771\/\u003c\/a\u003e\n      \u003c\/li\u003e\n    \u003c\/ul\u003e\n\n    \u003ch2\u003eTested by Accredited 3rd Party Labs\u003c\/h2\u003e\n    \u003cp\u003e\n      PureBulk's supplements are tested by accredited third party labs in the\n      USA to ensure their identity, purity and potency. To receive a copy of\n      these test results or any other PureBulk supplement please fill out the\n      \u003ca href=\"\/pages\/coa-request\"\u003eCOA request form\u003c\/a\u003e found\n      \u003ca href=\"\/pages\/coa-request\"\u003ehere\u003c\/a\u003e.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n  \u003c!-- end product-information--description --\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cp\u003e\n    \u003cstrong\u003e*NOTE: These statements have not been evaluated by the Food and Drug\n      Administration. This product is not intended to diagnose, treat, cure or\n      prevent any disease.\u003c\/strong\u003e\n  \u003c\/p\u003e\n\u003c\/div\u003e","brand":"purebulkinc","offers":[{"title":"Bags \/ 100 grams","offer_id":14279864057905,"sku":"10666","price":17.71,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 250 grams","offer_id":14279864090673,"sku":"10668","price":38.02,"currency_code":"USD","in_stock":false},{"title":"Bags \/ 500 grams","offer_id":14279864123441,"sku":"10670","price":68.87,"currency_code":"USD","in_stock":false},{"title":"Bags \/ 1 kilogram","offer_id":14279864156209,"sku":"10667","price":124.15,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6379\/6273\/files\/M36736-PureBulk.com_1.png?v=1744899792"},{"product_id":"pomegranate-extract-40-ellagic-acid","title":"Pomegranate Extract (40% Ellagic Acid)","description":"\u003cdiv class=\"row supplement product-information\"\u003e\n  \u003ch4 class=\"nm uppercase\"\u003eSupplement Facts \u0026amp; Directions\u003c\/h4\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003cdiv class=\"facts\"\u003e\n      \u003ch2\u003eSupplement Facts\u003c\/h2\u003e\n      \u003cspan\u003e Serving Size: 800 milligrams \u003c\/span\u003e \u003cbr\u003e\n      \u003cspan\u003eServings Per Container: Varies\u003c\/span\u003e\n      \u003chr class=\"topHr\"\u003e\n      \u003ctable\u003e\n        \u003cthead\u003e\n          \u003ctr\u003e\n            \u003cth\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/th\u003e\n            \u003cth\u003e\u003cstrong class=\"go-right\"\u003e% Daily Value*\u003c\/strong\u003e\u003c\/th\u003e\n          \u003c\/tr\u003e\n        \u003c\/thead\u003e\n        \u003ctbody\u003e\n          \u003ctr\u003e\n            \u003ctd\u003e\n              Pomegranate (\u003ci\u003ePunica granatum\u003c\/i\u003e) Extract (hulls) 800 mg \u003cbr\u003e\n              (standardized to contain 40% Ellagic Acid)\n            \u003c\/td\u003e\n            \u003ctd class=\"go-right\"\u003e†\u003c\/td\u003e\n          \u003c\/tr\u003e\n        \u003c\/tbody\u003e\n      \u003c\/table\u003e\n      \u003chr class=\"bottomHr\"\u003e\n      \u003cdiv class=\"factsNotes\"\u003e\n        \u003cp\u003e\n          * Percent Daily Values are based on a 2,000 calorie diet.\u003cbr\u003e† Daily\n          Value Not Established \u003cbr\u003e‡ These supplement facts may vary from the\n          product you receive. Please call for exact numbers.\n        \u003c\/p\u003e\n      \u003c\/div\u003e\n    \u003c\/div\u003e\n  \u003c\/div\u003e\n  \u003c!--end supp facts--\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003cp\u003e\n      \u003cspan class=\"directionsSpan\"\u003eOther Ingredients: \u003c\/span\u003eMaltodextrin (flow\n      agent 1-5%)\n    \u003c\/p\u003e\n    \u003cp style=\"display: none\"\u003e\u003cspan class=\"directionsSpan\"\u003eContains:\u003c\/span\u003e\u003c\/p\u003e\n    \u003cp\u003e\n      \u003cspan class=\"directionsSpan\"\u003eFree of: \u003c\/span\u003e Soy, Dairy, Yeast, \u0026amp;\n      Gluten.\u003cbr\u003e\n    \u003c\/p\u003e\n    \u003cp\u003e\n      \u003cspan class=\"directionsSpan\"\u003eDirections: \u003c\/span\u003e As a dietary supplement,\n      take 800 mg (1\/4 tsp) twice daily, or as directed by a physician.\u003cbr\u003e\n    \u003c\/p\u003e\n    \u003cp\u003e\n      \u003cspan class=\"directionsWarning\"\u003eWarning: \u003c\/span\u003eIf you are pregnant,\n      nursing, taking any medications or have any medical condition consult your\n      physician before use. Keep out of reach of children. Store in a cool, dark\n      \u0026amp; dry place.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- split --\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003ch4 id=\"ProductDetails\" class=\"nm uppercase\"\u003e\n      \u003ca style=\"color: #7d7d7d !important\" name=\"ProductDetails\"\u003e\u003c\/a\u003eProduct\n      Details\n    \u003c\/h4\u003e\n\n    \u003ch2\u003eWhat is Pomegranate Extract?\u003c\/h2\u003e\n    \u003cp\u003e\n      Pomegranates are round fruits with a spongy inner membrane (mesocarp)\n      packed with juicy seeds (arils). Pomegranates can contain between 200 and\n      1400 seeds and range in size from a lemon to a grapefruit. The husk and\n      seeds of a pomegranate are a red-purple color, and the juice often leaves\n      a permanent stain on clothing. The name comes from the medieval Latin\n      words for apple (pōmum) and seeded (\u003cem\u003egrānātum\u003c\/em\u003e).\n    \u003c\/p\u003e\n\n    \u003ch2\u003eWhat is Ellagic Acid?\u003c\/h2\u003e\n    \u003cp\u003e\n      Pomegranates have a tart flavor due to their low pH level and high\n      polyphenol content. Ellagitannins, also known as punicalagins, are\n      polyphenols with potent antioxidant properties. Once consumed, the body\n      metabolizes them into another antioxidant compound called ellagic acid.\n      The name ellagic acid comes from the French term \u003cem\u003eacide ellagique\u003c\/em\u003e,\n      which derives from the word galle spelled in reverse. The reversal is a\n      nod to plant galls, a source of ellagic acid, and to distinguish the\n      compound from the French term for gallic acid, \u003cem\u003eacide gallique\u003c\/em\u003e.\n    \u003c\/p\u003e\n\n    \u003cp\u003e\n      PureBulk's pomegranate extract is standardized to at least 40% ellagic\n      acid.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--split--\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003ch2\u003ePotential Benefits of Pomegranate Extract (40% Ellagic Acid)\u003c\/h2\u003e\n    \u003ch4\u003ePomegranate Extract as an Antioxidant\u003c\/h4\u003e\n    \u003cp\u003e\n      Antioxidants fight and protect cells from free radical damage. Free\n      radicals are a normal part of human biology, but too many of them can\n      damage cells and lead to chronic health problems. Ellagic acid is a\n      natural phenolic antioxidant that protects fatty acids and other lipids\n      from damage by inhibiting hydroxyl radicals from stealing electrons. It’s\n      also an effective free radical scavenger, and it may inhibit the spread\n      and growth of unhealthy cells.\n    \u003c\/p\u003e\n\n    \u003ch4\u003ePomegranate Extract as an Anti-Inflammatory\u003c\/h4\u003e\n    \u003cp\u003e\n      Too many free radicals cause oxidative stress and contribute to long-term\n      inflammation. Inflammation is also a common side effect of free radical\n      damage. Chronic inflammation damages health and can cause or worsen\n      numerous health conditions. Ellagitannins have shown anti-inflammatory\n      effects in animal studies, as has pomegranate extract in both in vitro and\n      in vivo studies. Another study found that pomegranate’s active compounds\n      reduced several biochemical markers of inflammation, including\n      prostaglandin E2 and interleukin.\n    \u003c\/p\u003e\n\n    \u003cp\u003e\n      Reducing inflammation has several other potential health benefits.\n      Reducing inflammation and oxidative stress promotes heart health by\n      supporting artery function and inhibiting plaque buildup. It also exerts\n      neuroprotective effects, as oxidative stress and inflammation worsen\n      certain neurological conditions.\n    \u003c\/p\u003e\n\n    \u003ch4\u003ePomegranate Extract and Exercise Endurance\u003c\/h4\u003e\n    \u003cp\u003e\n      Pomegranate extract may increase how long individuals can work out before\n      they become tired. For example, one study found that taking pomegranate\n      extract before working out increased participants’ time to exhaustion by\n      12%. Another study found that pomegranate extract also assisted with\n      recovering from workouts.\n    \u003c\/p\u003e\n\n    \u003ch4\u003ePomegranate Benefits for Skin\u003c\/h4\u003e\n    \u003cp\u003e\n      As an antioxidant, pomegranate extract can protect skin from prematurely\n      aging due to free radical damage, oxidative stress, and UV exposure.\n      Pomegranate extract is also able to defend skin from the photodamage by\n      neutralizing UV radicals and inhibiting UV rays from penetrating the skin.\n      It also improves the skin’s resilience against damaging UVB rays.\n      Pomegranate extract may help with skin pigmentation caused by excessive\n      sun exposure as well.\n    \u003c\/p\u003e\n\n    \u003ch2\u003ePotential Side Effects of Pomegranate Extract\u003c\/h2\u003e\n    \u003cp\u003e\n      Pomegranate extract is generally safe, as it is a natural plant extract.\n      Human and animal studies have reported no side effects from taking\n      pomegranate extract. Ellagic acid may interact with P450 enzymes and\n      inhibit the metabolism of certain medications, including blood thinners,\n      statins, or antipsychotics. Speak with a medical professional before\n      starting any new supplements.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--split--\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cdiv class=\"column product-information--description\"\u003e\n    \u003cul\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5079168\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5079168\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"http:\/\/artflx.uchicago.edu\/cgi-bin\/dicos\/pubdico1look.pl\"\u003ehttp:\/\/artflx.uchicago.edu\/cgi-bin\/dicos\/pubdico1look.pl\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28608832\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/28608832\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28125044\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/28125044\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28867799\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/28867799\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11902978\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/11902978\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31298147\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/31298147\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24949028\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/24949028\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23359482\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/23359482\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33671442\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/33671442\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23320197\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/23320197\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31892167\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/31892167\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26559394\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/26559394\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7918969\/\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7918969\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25051173\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/25051173\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30350760\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/30350760\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5237561\/\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5237561\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31908068\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/31908068\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6098906\/\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6098906\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3288507\/\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3288507\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"http:\/\/ncbi.nlm.nih.gov\/labs\/pmc\/articles\/PMC6787198\/\"\u003ehttp:\/\/ncbi.nlm.nih.gov\/labs\/pmc\/articles\/PMC6787198\/\u003c\/a\u003e\n      \u003c\/li\u003e\n      \u003cli\u003e\n        \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4007340\/\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4007340\/\u003c\/a\u003e\n      \u003c\/li\u003e\n    \u003c\/ul\u003e\n\n    \u003ch2\u003eTested by Accredited 3rd Party Labs\u003c\/h2\u003e\n    \u003cp\u003e\n      PureBulk's supplements are tested by accredited third party labs in the\n      USA to ensure their identity, purity and potency. To receive a copy of\n      these test results or any other PureBulk supplement please fill out the\n      \u003ca href=\"\/pages\/coa-request\"\u003eCOA request form\u003c\/a\u003e found\n      \u003ca href=\"\/pages\/coa-request\"\u003ehere\u003c\/a\u003e.\n    \u003c\/p\u003e\n  \u003c\/div\u003e\n  \u003c!-- end product-information--description --\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"row product-information\"\u003e\n  \u003cp\u003e\n    \u003cstrong\u003e*NOTE: These statements have not been evaluated by the Food and Drug\n      Administration. This product is not intended to diagnose, treat, cure or\n      prevent any disease.\u003c\/strong\u003e\n  \u003c\/p\u003e\n\u003c\/div\u003e\n","brand":"purebulkinc","offers":[{"title":"Bags \/ 100 grams","offer_id":14280803582001,"sku":"11204","price":9.63,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 250 grams","offer_id":14294887563313,"sku":"11206","price":20.6,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 500 grams","offer_id":14294887596081,"sku":"11208","price":37.16,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 1 kilogram","offer_id":14294887628849,"sku":"11205","price":77.0,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 1.5 kilograms","offer_id":14294887661617,"sku":"11203","price":95.48,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6379\/6273\/products\/pomegranate-extract.jpg?v=1653580161"},{"product_id":"l-norvaline","title":"L-Norvaline","description":"\u003cdiv class=\"row supplement product-information\"\u003e\n    \u003ch4 class=\"nm uppercase\"\u003eSupplement Facts \u0026amp; Directions\u003c\/h4\u003e\n    \u003cdiv class=\"column product-information--description\"\u003e\n        \u003cdiv class=\"facts suppfacts supplement-powder\"\u003e\n            \u003ch2\u003eSupplement Facts\u003c\/h2\u003e\n            \u003cspan\u003e Serving Size: 400 milligrams\u003c\/span\u003e \u003cbr\u003e \u003cspan\u003eServings Per Container: Varies\u003c\/span\u003e\n            \u003chr class=\"topHr\"\u003e\n            \u003ctable\u003e\n                \u003cthead\u003e\n                    \u003ctr\u003e\n                        \u003cth\u003e\u003cstrong\u003eAmount Per Serving\u003c\/strong\u003e\u003c\/th\u003e\n                        \u003cth\u003e\u003cstrong class=\"go-right\"\u003e% Daily Value*\u003c\/strong\u003e\u003c\/th\u003e\n                    \u003c\/tr\u003e\n                \u003c\/thead\u003e\n                \u003ctbody\u003e\n                    \u003ctr\u003e\n                        \u003ctd\u003eL-Norvaline 400 mg\u003c\/td\u003e\n                        \u003ctd class=\"go-right\"\u003e †\u003c\/td\u003e\n                    \u003c\/tr\u003e\n                \u003c\/tbody\u003e\n            \u003c\/table\u003e\n            \u003chr class=\"bottomHr\"\u003e\n            \u003cdiv class=\"factsNotes\"\u003e\n                \u003cp\u003e* Percent Daily Values are based on a 2,000 calorie diet.\u003cbr\u003e† Daily Value Not Established \u003cbr\u003e‡\n                    These supplement facts may vary from the product you receive. Please call for exact numbers.\u003c\/p\u003e\n            \u003c\/div\u003e\n        \u003c\/div\u003e\n    \u003c\/div\u003e\n    \u003c!--end supp facts--\u003e\n    \u003cdiv class=\"column product-information--description\"\u003e\n        \u003cdiv class=\"suppfacts supplement-powder\"\u003e\n            \u003cp\u003e\u003cspan class=\"directionsSpan\"\u003eOther Ingredients: \u003c\/span\u003eNone\u003c\/p\u003e\n            \u003cp style=\"display: none;\"\u003e\u003cspan class=\"directionsSpan\"\u003eContains:\u003c\/span\u003e\u003c\/p\u003e\n            \u003cp\u003e\u003cspan class=\"directionsSpan\"\u003eFree of: \u003c\/span\u003eAdded Sugar, Soy, Dairy, Yeast, Gluten, Corn \u0026amp; Additives.\n            \u003c\/p\u003e\n            \u003cp\u003e\u003cspan class=\"directionsSpan\"\u003eDirections: \u003c\/span\u003eAs a dietary supplement, take 400 mg (1\/8 tsp) daily or\n                as directed by a physician.\u003c\/p\u003e\n            \u003cp\u003e\u003cspan class=\"directionsWarning\"\u003eWarning: \u003c\/span\u003eIf you are pregnant, nursing, taking any medications or\n                have any medical condition consult your physician before use. Keep out of reach of children.\u003c\/p\u003e\n        \u003c\/div\u003e\n    \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!-- split --\u003e\n\u003cdiv class=\"row product-information\"\u003e\n    \u003cdiv class=\"column product-information--description\"\u003e\n        \u003ch4 id=\"ProductDetails\" class=\"nm uppercase\"\u003e\n            \u003ca style=\"color: #7d7d7d !important\" name=\"ProductDetails\"\u003e\u003c\/a\u003eProduct\n            Details\n        \u003c\/h4\u003e\n\n        \u003ch2\u003eWhat is L-Norvaline\u003c\/h2\u003e\n        \u003cp\u003e\n            L-norvaline is a non-essential amino acid and an isomer of the\n            \u003ca href=\"https:\/\/purebulk.com\/products\/branched-chain-amino-acids-bcaa-instantized\"\u003ebranched-chain amino\n                acid\u003c\/a\u003e\n            (BCAA) \u003ca href=\"https:\/\/purebulk.com\/products\/l-valine\"\u003evaline\u003c\/a\u003e.\n            Isomers share the same number of atoms and molecules of each element\n            component but have distinct arrangements. Unlike valine, l-norvaline is an\n            unbranched-chain amino acid. It’s a common ingredient in pre-workout\n            supplement stacks due to its interactions with\n            \u003ca href=\"https:\/\/purebulk.com\/products\/l-arginine-base\"\u003earginine\u003c\/a\u003e.\n            Recent research also shows that l-norvaline has neuroprotective properties\n            that may support long-term cognitive health.\n        \u003c\/p\u003e\n    \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--split--\u003e\n\u003cdiv class=\"row product-information\"\u003e\n    \u003cdiv class=\"column product-information--description\"\u003e\n        \u003ch2\u003ePotential L-Norvaline Benefits\u003c\/h2\u003e\n        \u003ch4\u003eL-Norvaline and Exercise Performance\u003c\/h4\u003e\n        \u003cp\u003e\n            L-Norvaline may enhance athleticism by inhibiting arginase enzymes. These\n            enzymes break down arginine into l-ornithine and urea as part of the urea\n            cycle to remove ammonia buildup. However, arginase competes with nitric\n            oxide synthase (NOS) enzymes for arginine. Arginase also has more than\n            1000 times the activity of NOS enzymes. NOS enzymes are essential for\n            nitric oxide synthesis, and too much arginase can create a nitric oxide\n            deficiency.\n        \u003c\/p\u003e\n        \u003cp\u003e\n            By inhibiting arginase, l-norvaline helps preserve arginine levels to use\n            for nitric oxide production. One study found that norvaline boosted nitric\n            oxide production by 55%. Nitric oxide is a vasodilator that improves blood\n            flow, relaxes blood vessels, and improves nutrient and oxygen delivery\n            throughout the body. Fueling the muscles with more nutrients and oxygen\n            may improve exercise performance.\n        \u003c\/p\u003e\n        \u003ch4\u003eL-Norvaline and Heart Health\u003c\/h4\u003e\n        \u003cp\u003e\n            L-Norvaline exerts anti-inflammatory effects on the endothelial cells\n            found in blood vessels and the heart. It also provides a layer of\n            protection for the endothelium by acting as an arginase inhibitor.\n            Additionally, l-norvaline supports nitric oxide production, which promotes\n            vasodilation and can help reduce the pressure exerted against artery walls\n            when pumping blood.\n        \u003c\/p\u003e\n        \u003ch2\u003ePotential L-Norvaline Side Effects\u003c\/h2\u003e\n        \u003cp\u003e\n            Norvaline has fewer scientific studies compared to other alpha amino\n            acids. However, research is ongoing, and the existing norvaline studies\n            have not reported any side effects. Some individuals may experience mild\n            gastrointestinal side effects, such as nausea or upset stomach.\n            Individuals taking blood pressure medication should consult with a\n            physician before taking norvaline supplements.\n        \u003c\/p\u003e\n    \u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--split--\u003e\n\u003cdiv class=\"row product-information\"\u003e\n    \u003cdiv class=\"column product-information--description\"\u003e\n        \u003ch2\u003eReferences\u003c\/h2\u003e\n\n        \u003cul\u003e\n            \u003cli\u003e\n                \u003ca href=\"https:\/\/www.worldcat.org\/oclc\/46872308\"\u003ehttps:\/\/www.worldcat.org\/oclc\/46872308\u003c\/a\u003e\n            \u003c\/li\u003e\n            \u003cli\u003e\n                \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3124670\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3124670\u003c\/a\u003e\n            \u003c\/li\u003e\n            \u003cli\u003e\n                \u003ca href=\"https:\/\/journals.physiology.org\/doi\/full\/10.1152\/ajpheart.1998.274.1.H342\"\u003ehttps:\/\/journals.physiology.org\/doi\/full\/10.1152\/ajpheart.1998.274.1.H342\u003c\/a\u003e\n            \u003c\/li\u003e\n            \u003cli\u003e\n                \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2664787\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2664787\u003c\/a\u003e\n            \u003c\/li\u003e\n            \u003cli\u003e\n                \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32149110\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/32149110\u003c\/a\u003e\n            \u003c\/li\u003e\n            \u003cli\u003e\n                \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3682715\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3682715\u003c\/a\u003e\n            \u003c\/li\u003e\n            \u003cli\u003e\n                \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6557086\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6557086\u003c\/a\u003e\n            \u003c\/li\u003e\n            \u003cli\u003e\n                \u003ca href=\"https:\/\/link.springer.com\/article\/10.1007\/s13311-018-0669-5\"\u003ehttps:\/\/link.springer.com\/article\/10.1007\/s13311-018-0669-5\u003c\/a\u003e\n            \u003c\/li\u003e\n        \u003c\/ul\u003e\n\n        \u003ch2\u003eTested by Accredited 3rd Party Labs\u003c\/h2\u003e\n        \u003cp\u003e\n            PureBulk's supplements are tested by accredited third party labs in the\n            USA to ensure their identity, purity and potency. To receive a copy of\n            these test results or any other PureBulk supplement please fill out the\n            \u003ca href=\"\/pages\/coa-request\"\u003eCOA request form\u003c\/a\u003e found\n            \u003ca href=\"\/pages\/coa-request\"\u003ehere\u003c\/a\u003e.\n        \u003c\/p\u003e\n    \u003c\/div\u003e\n    \u003c!-- end product-information--description --\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"row product-information\"\u003e\n    \u003cp\u003e\n        \u003cstrong\u003e*NOTE: These statements have not been evaluated by the Food and Drug\n            Administration. This product is not intended to diagnose, treat, cure or\n            prevent any disease.\u003c\/strong\u003e\n    \u003c\/p\u003e\n\u003c\/div\u003e","brand":"purebulkinc","offers":[{"title":"Bags \/ 25 grams","offer_id":14284215550001,"sku":"10877","price":5.08,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 50 grams","offer_id":14294862430257,"sku":"10880","price":9.28,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 100 grams","offer_id":14294862463025,"sku":"10874","price":16.77,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 250 grams","offer_id":14294862495793,"sku":"10876","price":36.05,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 500 grams","offer_id":14294862528561,"sku":"10879","price":65.06,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 1 kilogram","offer_id":14294862561329,"sku":"10875","price":117.56,"currency_code":"USD","in_stock":false},{"title":"Capsules \/ 120ct 400mg Veg. Caps","offer_id":45867407605957,"sku":"14129","price":12.25,"currency_code":"USD","in_stock":true},{"title":"Capsules \/ 120ct 400mg Gel. Caps","offer_id":45867407638725,"sku":"14130","price":11.38,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6379\/6273\/files\/L-Norvaline.png?v=1761661744"},{"product_id":"benfotiamine","title":"Benfotiamine Powder","description":"\u003c!-- split --\u003e\n\u003cdiv class=\"row product-information\"\u003e\n\u003cdiv class=\"column product-information--description\"\u003e\n\u003ch4 class=\"nm uppercase\" id=\"ProductDetails\"\u003e\u003ca name=\"ProductDetails\" style=\"color: #7d7d7d !important;\"\u003e\u003c\/a\u003e\u003c\/h4\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch2\u003eWhat is Benfotiamine?\u003c\/h2\u003e\n\u003cp\u003eBenfotiamine is a derivative of vitamin B1 (thiamine). While B vitamins are naturally water-soluble, synthesized benfotiamine is fat-soluble. Once ingested, ecto-alkaline phosphatases dephosphorylate benfotiamine into S-benzoylthiamine, which thioesters enzymes hydrolyze into thiamine in the liver. Benfotiamine is stable and easier for the body to absorb than thiamine salts.\u003c\/p\u003e\n\u003c!--split--\u003e\n\u003cdiv class=\"row product-information\"\u003e\n\u003cdiv class=\"column product-information--description\"\u003e\n\u003ch2\u003eWhat is Benfotiamine?\u003c\/h2\u003e\n\u003cp\u003eBenfotiamine is a derivative of vitamin B1 (thiamine). While B vitamins are naturally water-soluble, synthesized benfotiamine is fat-soluble. Once ingested, ecto-alkaline phosphatases dephosphorylate benfotiamine into S-benzoylthiamine, which thioesters enzymes hydrolyze into thiamine in the liver. Benfotiamine is stable and easier for the body to absorb than thiamine salts.\u003c\/p\u003e\n\u003ch2\u003eVitamin B1 Deficiency Symptoms\u003c\/h2\u003e\n\u003cp\u003eBenfotiamine supplements increase cellular concentrations of thiamine diphosphate, another thiamine derivative and a cofactor that catalyzes several biological reactions. In animal studies, benfotiamine increased serum vitamin B1 levels five times greater than an equivalent dose of thiamine. As such, it’s an effective method for avoiding a vitamin B1 deficiency.\u003c\/p\u003e\n\u003cp\u003eSome individuals and medical conditions increase the risk of a B1 deficiency. These include consuming a lot of coffee or tea, eating raw fish regularly, eating a rice-based diet, alcoholism, dialysis, frequent use of diuretics, having diabetes, undergoing bariatric surgery, having a medical condition that inhibits nutrient absorption (e.g., celiac disease), and aging.\u003c\/p\u003e\n\u003cp\u003eVitamin B1 deficiency symptoms are often vague and can mimic other conditions, which makes it challenging to diagnose. Some health indicators of a B1 deficiency include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eLoss of appetite\u003c\/li\u003e\n\u003cli\u003eUnintentional weight loss\u003c\/li\u003e\n\u003cli\u003eFatigue\u003c\/li\u003e\n\u003cli\u003ePins and needles sensation in the hands\u003c\/li\u003e\n\u003cli\u003eTingling extremities\u003c\/li\u003e\n\u003cli\u003eLoss of coordination\u003c\/li\u003e\n\u003cli\u003eLoss of sensitivity in hands and feet\u003c\/li\u003e\n\u003cli\u003eBrain fog\u003c\/li\u003e\n\u003cli\u003eMemory loss\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003ePotential Benfotiamine Benefits\u003c\/h2\u003e\n\u003cdiv class=\"infobox\"\u003e\n\u003ch3\u003eBenfotiamine and Alpha Lipoic Acid\u003c\/h3\u003e\nOne study noted that benfotiamine synergized with \u003ca href=\"https:\/\/purebulk.com\/products\/alpha-lipoic-acid-r-ala-thioctic-acid\"\u003ealpha lipoic acid\u003c\/a\u003e to normalize AGEs levels and impede other damaging reactions.\u003c\/div\u003e\n\u003ch4\u003eBenfotiamine as an Antioxidant\u003c\/h4\u003e\n\u003cp\u003eBenfotiamine inhibits free radical damage, enhances antioxidant defenses, and reduces oxidative stress. It also has anti-inflammatory effects on brain cells, white blood cells, blood vessels, and nerves. It also helps regenerate, repair, and reduce cell death by altering the production of endothelial nitric oxide synthase (eNOS) enzymes and protein kinase B enzymes. It can support healthy cellular growth by changing how cells use energy.\u003c\/p\u003e\n\u003cp\u003eBenfotiamine boosts thiamine diphosphate, a cofactor the body needs to active transketolase. Transketolase is an enzyme that helps convert sugar into energy instead of harmful advanced glycation end products (AGEs). AGEs are the result of a protein or fat binding to sugar. They interfere with normal cell functioning, damage cells, cause premature aging, and can worsen or advance diabetes complications.\u003c\/p\u003e\n\u003ch4\u003eBenfotiamine for Pain Management\u003c\/h4\u003e\n\u003cp\u003eBenfotiamine has antinociceptive effects, meaning it blocks sensory neurons from detecting painful stimuli. Animal studies found benfotiamine reduced short-term pain (e.g., heat-related pain or burning sensations) and chronic pain. A human clinical trial noted benfotiamine supplements made a pronounced improvement in participants’ nerve pain. Other studies have reported that a combination of benfotiamine and \u003ca href=\"https:\/\/purebulk.com\/products\/pyridoxine-hcl-vitamin-b6\"\u003evitamin B6\u003c\/a\u003e is also effective for relieving nerve pain. Benfotiamine may improve joint mobility as well by reducing inflammation and pain.\u003c\/p\u003e\n\u003ch2\u003eBenfotiamine Side Effects\u003c\/h2\u003e\n\u003cp\u003eBenfotiamine does not appear to cause notable side effects based on the available scientific literature. However, some individuals may experience dizziness, nausea, or a dip in blood pressure. Individuals with sulfur sensitivities or allergies should not take benfotiamine, as it contains sulfur. Individuals should consult with a physician before taking new supplements.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c!--split--\u003e\n\u003cdiv class=\"row product-information\"\u003e\n\u003cdiv class=\"column product-information--description\"\u003e\n\u003ch4\u003eReferences\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23066179\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23066179\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18549472\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18549472\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/13782394\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/13782394\/\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23066179\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/23066179\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/1776825\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/1776825\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20188835\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/20188835\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8929745\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8929745\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18549472\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18549472\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28880548\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/28880548\/\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12592403\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12592403\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21511829\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21511829\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16416271\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16416271\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19768736\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19768736\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20107192\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20107192\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19943121\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19943121\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25695433\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25695433\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25849583\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25849583\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16936154\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16936154\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25695433\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25695433\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20219672\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20219672\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16359659\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/16359659\/\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23119057\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/23119057\/\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22128427\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/22128427\/\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9064269\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/9064269\/\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9791922\/\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/9791922\/\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23354008\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23354008\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23091724\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23091724\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18509620\"\u003ehttps:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18509620\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c!-- end product-information--description --\u003e\n\u003c\/div\u003e","brand":"purebulkinc","offers":[{"title":"Bags \/ 50 grams","offer_id":14306782871601,"sku":"13111","price":15.95,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 100 grams","offer_id":14306782904369,"sku":"13112","price":28.95,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 250 grams","offer_id":14306782937137,"sku":"13113","price":61.95,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 500 grams","offer_id":14306782969905,"sku":"13114","price":111.95,"currency_code":"USD","in_stock":true},{"title":"Bags \/ 1 kilogram","offer_id":14306783002673,"sku":"13115","price":201.95,"currency_code":"USD","in_stock":true},{"title":"Capsules \/ 120ct 200mg Gel. Caps.","offer_id":45867404787909,"sku":"13384","price":0.0,"currency_code":"USD","in_stock":false},{"title":"Capsules \/ 120ct 200mg Veg. Caps.","offer_id":45867404820677,"sku":"13386","price":13.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6379\/6273\/products\/benfotiamine.jpg?v=1654111304"},{"product_id":"inositol-hexanicotinate-bulk","title":"Inositol Hexanicotinate Powder Bulk 25kg","description":"\u003cp\u003e\u003c\/p\u003e","brand":"purebulkinc","offers":[{"title":"Default Title","offer_id":14307813916721,"sku":"10669","price":2659.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0012\/6379\/6273\/products\/inositol-hexanicotinate.jpg?v=1744899792"}],"url":"https:\/\/purebulk.com\/collections\/sales-specials.oembed?page=5","provider":"PureBulk, Inc.","version":"1.0","type":"link"}