N-acetyl L-cysteine (also known as NAC and acetylcysteine) is the acetylated form of L-cysteine. L-Cysteine
is a semi-essential, sulfur-containing amino acid that is an important structural component in many
proteins. Vegans may struggle to obtain enough cysteine from their diet, as it is most often found in eggs,
poultry, and beef.
L-cysteine forms bonds with glutamine and glycine to synthesize glutathione, an antioxidant tripeptide.
However, external factors like free radicals, illness, and stress deplete glutathione levels. NAC
supplements boost the availability of l-cysteine, which accelerates glutathione production.
Potential Benefits of NAC Supplements
Supplementation of L-cysteine via N-acetyl L-cysteine may support the immune system by improving the
availability of glutathione. Glutathione is a powerful antioxidant that scavenges free radicals and
activates natural killer cells. When glutathione levels deplete, the body is much more vulnerable to free
radical damage. Boosting glutathione levels can help repair this damage.
NAC also reduces the damaging effects of oxidative stress, which may support heart health. NAC may also
benefit heart health by improving blood flow and increasing glutathione concentrations in red blood cells.
Did You Know?
NAC synergizes with green
to reduce the damage caused by oxidized LDL cholesterol.
NAC supplements may support the body’s detoxification process and liver health. Toxic substances often
suppress glutathione levels, which NAC may counteract by preserving glutathione availability.
NAC also has anti-inflammatory and expectorant properties. Its ability to reduce inflammation, loosen mucus,
and boost glutathione levels may improve lung function. NAC’s anti-inflammatory properties also extend to
fat cells, which may help regulate blood sugar.
NAC may provide dermatological benefits as well. NAC accelerates wound healing, which may help acne lesions
to resolve faster. NAC may also improve acne healing time by reducing free radicals. NAC may also help
restore the skin’s natural barrier and reduce skin inflammation.
When to Take NAC: Morning or Night?
Individuals can take NAC supplements in the morning or at night. However, NAC supplements metabolize into the
amino acid l-cysteine. As certain foods can affect amino acid absorption, individuals should take NAC on an
empty stomach. Wait at least one hour after eating for maximum absorption. Keep NAC in a cool and dry
location to maximize its shelf-life.
Potential NAC Supplement Side Effects
NAC is well-tolerated by most individuals. Excessive doses of NAC may cause nausea, vomiting, constipation,
or diarrhea. Individuals taking blood thinners should not take NAC, as it may slow clotting.
Tested by Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity
and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.