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What is Gamma Aminobutyric Acid (GABA)?

GABA is among the most important of all nonessential nutrients. It is used by the brain to promote calmness and tranquility through brain metabolism. The amino acid was first discovered in 1883 in Berlin.

GABA is the most widespread inhibitory neurotransmitter in the brain. It is formed from glutamic acid with the help of vitamin B6.

In human physiology, a neurotransmitter (Wikipedia) is a substance that facilitates communication between nerve cells in the central nervous system (CNS).

Glutamic acid decarboxylase (GAD) catalyzes the formation of GABA from glutamic acid. GAD requires vitamin B6 (pyridoxal phosphate) as a coenzyme to manage the levels of GABA.

GABA is also important in mediating muscle activities and in triggering certain glands located throughout the body.

The production and synthesis of GABA is limited and controlled by B-vitamin compounds (Wikipedia), particularly B6. To ensure adequate GABA levels, food sources high in both protein and vitamin B6 are needed. GABA is abundant in several food sources, with the richest concentrations being in fish (particularly mackerel) and wheat bran.

Benefits of Gamma Aminobutyric Acid (GABA)

GABA, the primary inhibitory neurotransmitter in the central nervous system, is responsible for blocking the transmission of an impulse from one cell to another. GABA’s main purpose is to prevent the over-firing of the nerve cells and to decrease overall neuron activities occurring within the CNS.

GABA promotes normal brain function by helping to block stress-related messages from reaching receptor sites in the central nervous system.

Along with niacinamide(B3) and inositol, GABA is essential for brain metabolism.

In the United States, the GABA analog gabapentin has been approved for the treatment of epileptic seizures and post-herpetic neuralgia.

Purity and Concentration of Gamma Aminobutyric Acid (GABA)

This GABA (Gamma-AminoButyric-Acid) powder contains no fillers, taste additives or anti-caking agents.

Potential Side Effects of Gamma Aminobutyric Acid (GABA)

GABA appears to be safe when taken as directed. In high quantities, GABA can increase anxiety and insomnia. It may also cause numbness around the mouth and tingling in the extremities, mild nausea, a slight shortness of breath that lasts for a few minutes and temporary tingling of the skin. In extreme cases, GABA may cause a chemical imbalance in the brain, resulting in seizures. Toxicities, however, are rare.

The body needs a supply of all the amino acids in order to effectively create and utilize proteins. Those supplementing any of the amino acids should have a balanced intake of the other amino acids.

Those with liver or kidney disease should not take this or any other amino acid supplement without first consulting a physician.

Suggested Use of Gamma Aminobutyric Acid (GABA)

Individual preferences vary. The suggested serving size for GABA is 750 milligrams taken once or twice daily on an empty stomach prior to sleep. As you can see on the full bulk density/volumetric conversion chart for gamma amino butyric acid (GABA) here, a serving of a slightly rounded 1/4 teaspoon is about equal to 750 milligrams.

Bioavailability, Mixing and Solubility of Gamma Aminobutyric Acid (GABA)

This product dissolves quickly in water and has almost no taste. Mix with water or juice and drink.

How should I store it?

You will receive a resealable bag of this powder. Store in a cool, dry area protected from light. Reseal after each use.

References & Further Research

PubMed: Relaxation and immunity enhancement effects of gamma-aminobutyric acid administration in humans

Wikipedia: Gamma Aminobutyric Acid

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NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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