Pure Bulk Niacin USP 1kg - $12.25 : Purebulk.com, Wholesale Nutritional Supplements

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Products :: Niacin USP :: Niacin USP 250g

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$12.25

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Unit Weight: 250 grams
Unit Volume: 500 cc

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Certificate of Analysis

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Volumetric Equivalents

Niacin USP, 250 grams

This pharmaceutical grade Niacin (also referred synonymously as Vitamin B3 or Nicotinic Acid) is assayed by the manufacturer to be 99.92% product. You will receive a double sealed labeled bulk polyethylene bag containing 250 grams of this white powder product. Two hundred and fifty grams is also 250 grams, or approximately 8.818 ounces by weight. You will not receive the fancy retail packaging, but you will receive a great deal at or below wholesale prices for a high purity bulk quantity of this product. This product dissolves quickly in water and has a sour taste that is only slightly bitter. Just mix your usual dose (not to exceed 500mg) with water or juice and drink.

Niacin when taken in sufficiently large doses (but not to exceed 500mg in a single dose) blocks the breakdown of fats and can have a dramatic lowering effect on blood lipid levels. Niacin is occasionally prescribed by physicians and taken for the treatment of hyperlipidemia because oral Niacin can reduce blood levels of VLDL (very-low-density lipoprotein) which are the precursors for LDL (the bad cholesterol). Because niacin blocks the breakdown of fats it can cause a decrease in free fatty acids in the blood, and thereby lead to decreased hepatic (liver) secretion of VLDL. When lowering VLDL blood levels niacin also has the effect of increasing the level of HDL (high density lipoproteins which is the good cholesterol). See: Anne White Robinson, DNS, RN; Helen L. Sloan, RN, CS, GNP, DNS; Gary Arnold, MD "Use of Niacin in the Prevention and Management of Hyperlipidemia", Prog Cardiovasc Nurs 16(1):14-20, 2001. See also: Guyton, J R : Capuzzi, D M "Treatment of hyperlipidemia with combined niacin-statin regimens. " Am-J-Cardiol. 1998 Dec 17; 82(12A): 82U-84U; discussion 85-86U.

Niacin supplementation and Hyperlipidemia: If you have high cholesterol or elevated blood lipid levels and are currently taking prescription drugs to treat your condition you should consult your prescribing physician before taking this product.

Niacin Flushing: This pharmaceutical grade bulk Niacin powder is the immediate release form that can cause niacin flushing in doses larger than 50 to 100 milligrams. The typical dose that causes mild flushing varies from individual to individual but is typically between 50 and 100 milligrams. When the dose taken is larger than 100 to 200 milligrams intense flushing, redness, itching, and irritation can occasionally occur. Be careful not to take doses that are too large and to increase your dose gradually to avoid uncomfortable flushing. Doses greater than 250 milligrams will generally result in marked and sometimes uncomfortable flushing. Doses larger than 1 but less than 2 grams will likely result in extreme flushing discomfort and the remote possibility of emergency medical treatment. Doses larger than 2 to 5 grams can potentially be life threatening.

Recommended doses for Niacin vary from the daily allowance to as much as 500 milligrams three times per day (totaling 1.5 grams per day). Since Niacin is also Vitamin B3, the daily allowance is 2-12 milligrams for children, 14 milligrams for women, 16 milligrams for men, and 18 milligrams for pregnant or breast-feeding women. However, as a dietary supplement taken for the purpose of lowering blood cholesterol, Niacin is frequently taken in multiple smaller doses that when combined will total up to 1 to 1.5 grams per day. However, care must be taken be individuals not to exceed their tolerated dose as niacin flushing can accompany large doses of 50 to 100 milligrams or larger. Niacin flushing can range from a mildly warm peripheral feeling in the skin to an extremely uncomfortable feeling of intense heat, burning, and itching than can last for several minutes to as long as 1 or 2 hours. In some cases single doses larger than 2 grams can be life threatening. Take care to adjust your divided daily dose (taken three times per day) and to cut back your dose if you experience uncomfortable flushing.

Aspirin may reduce Niacin flushing: One recent study by Auburn University of Alabama found that taking 325 milligrams aspirin 30 minutes prior to taking 500 milligrams of immediate release niacin significantly reduced the uncomfortable symptoms associated with niacin flushing. Most people also find that flushing symptoms are reduced when taken at meal-time. See: Paul W. Jungnickel, PhD,1 Pierre A. Maloley, PharmD,2,3 Elton L. Vander Tuin, PharmD,5 Tom E. Peddicord, PharmD,4 and James R. Campbell, "Effect of Two Aspirin Pretreatment Regimens on Niacin-Induced Cutaneous Reactions", MD3; J Gen Intern Med. 1997 October; 12(10): 591-596. doi: 10.1046/j.1525-1497.1997.

WARNING! Taking 2 grams Niacin or more in a single dose can result in potentially life threatening complications from flushing. Do not take more than 500 milligrams Niacin in a single dose as extreme discomfort associated with flushing may be experienced. Smaller doses of more than 50 to 100 milligrams can also result in uncomfortable flushing for some people. Taking a single 325mg aspirin 30 minutes before taking a dose of up to 500mg Niacin can help to reduce flushing symptoms (see citation above).

$12.25