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What is Hyaluronic Acid?

Hyaluronic acid is aptly described as "nature's moisturizer." Aside from being the normal lubricant in human joints (it is one of the most hydrophilic molecules in nature), hyaluronic acid affects the way the body responds to injury. Poor lubrication due to low hyaluronic acid (HA) levels is the leading cause of painful joints.

Also called sodium hyaluronate, HA is a component of connective tissue belonging to a family of proteins known as glycosaminoglycans. They aid in the body's water maintenance, providing essential moisture for body processes and molecular transport.

Hyaluronic acid's main function is to cushion and lubricate. It occurs naturally throughout the human body. It is a key component of cartilage concentrated in the synovial joint fluids (where it acts as a lubricant, shock absorber, metabolic medium and filter), the heart valves, in subcutaneous (skin) tissue where it functions as a cementing agent, and the eyes.

As a supplement, HA is a white, odorless powder also known as na hyaluronate. It supports the immune system by acting as an antioxidant.

Benefits of Hyaluronic Acid

Hyaluronic acid can be taken internally as a nutritional supplement for joint health or topically as a skin moisturizer. In topical applications, hyaluronic acid supports smooth, elastic skin, and it is used in many cosmetics such as make-up and moisturizing creams. Basically, HA helps to keep water in the skin.

Hyaluronic Acid Purity and Concentration

This food grade hyaluronic acid white powder does not contain any fillers, additives or anti-caking agents. It is assayed by the manufacturer to contain at least 43% of one of the active components, glucuronic acid. Keep the powder in a cool, dry, dark place for storage. Reseal after each use.

Potential Side Effects of Hyaluronic Acid

No known side effects exist, and clinical trials have shown that negative reactions are rare. As always, it is advisable to check with a doctor before deciding to take HA or any other type of supplement.

Suggested Use of Hyaluronic Acid

The suggested serving size is 100 milligrams twice per day. For measurement of this product use an accurate milligram weight scale.

Bioavailability, Mixing and Solubility of Hyaluronic Acid

Hyaluronic 1% Solution Preparation: To prepare 12 fluid ounces of 1% (by weight) Hyaluronic Acid solution, be aware it should only be dissolved in cold water. Never attempt to dissolve Hyaluronic Acid in hot or room temperature water. You will need the following items:

• 3.56 grams Hyaluronic Acid Powder.
  
• 12 fluid ounces cold distilled water.
  
• 16 fluid ounce or larger capacity wide mouth glass or plastic water bottle with a tightly sealing lid.
  
• Gram weight measuring scale with an accuracy of 0.01 gram and a capacity of 100 grams.
  
• Pint sized glass or plastic measuring cup.
  
• A wide-range cooking thermometer (that can go down to freezing)

Directions: 1. Measure out 12 fluid ounces distilled water and pour into water bottle. 2. Place in refrigerator for about 4 hours. 3. Measure the temperature of water to confirm water temperature is 39°F (4°C) or less. 4. Measure 3.56 grams Hyaluronic Acid powder (approximately two level teaspoons). 5. Add the Hyaluronic Acid powder into the water bottle on top of the cold water. 6. Seal the bottle lid tightly and shake the bottle a few times. The Hyaluronic Acid powder will not appear to dissolve but will clump together in floating white masses. This is normal. 7. Place the water bottle with the Hyaluronic Acid powder and cold water into the refrigerator (but do not freeze). 8. Periodically, about every two to four hours, shake the bottle and then place immediately back into refrigerator. After 4 to 8 hours you will notice that the Hyaluronic Acid clumps are turning clear and dispersing into solution. After 12 to 24 hours the Hyaluronic Acid will be completely dissolved forming a thickened and gelatinous liquid with a viscosity between maple syrup and honey, but still pourable. Yield: For internal use a level tablespoon will net approximately 150 milligrams Hyaluronic Acid.

Hyaluronic Acid solution storage: You can store your 1% Hyaluronic Solution in the refrigerator and use it as needed. This HA solution if prepared and stored properly should keep for a minimum of 48 to 72 hours with refrigeration. You should not attempt to store your HA solution at room temperature without the addition of preservatives. The maximum safe time you can keep your HA solution refrigerated without spoilage will depend upon your ability to keep the solution sterile. Microbial contamination of your solution will cause it to spoil and lose its thickness (viscosity). If over time the solution becomes thin or loses its thickness and viscosity it has spoiled and should be discarded.

Adding preservatives to your Hyaluronic Acid solution: To store this HA solution refrigerated for periods of time longer than 3 days you should start this recipe by first adding preservatives to the distilled water. Two such preservatives we inventory are Ascorbic Acid (Vitamin C) and DMAE Bitartrate. Add and dissolve approximately 6 grams Ascorbic Acid and 3 grams DMAE Bitartrate to 12 fluid ounces distilled water at room temperature. After both powders are completely dissolved chill the 12 fluid ounces to 39°F (4°C) (check with a wide-range cooking thermometer) and then follow the recipe directions above. When taken orally this preserved HA solution will net the following nutritional supplements per level tablespoon: Hyaluronic Acid 150mg, Ascorbic Acid 250mg, DMAE Bitartrate 125mg.

Internal Use: Hyaluronic Acid can be taken internally to support joint and connective tissue health. Hyaluronic Acid powder can be placed directly into the mouth and swallowed with water, or you can mix your dose in food or juice and consume. But for optimal results and bioavailability take a measured amount of a prepared 1% Hyaluronic Acid solution. See above for methods of preparing a 1% Hyaluronic Acid Solution which will approximate 150 milligrams Hyaluronic Acid per 1 level tablespoon of 1% solution.

Topical Use: Hyaluronic Acid can also be applied topically to the skin as a moisturizing agent. Topical use is usually recommended in concentrations between 0.5% but not to exceed 1%.

NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.