What is Chondroitin Sulfate?
Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) and a significant component of cartilage. GAGs are
intricate polysaccharides most often found in connective tissues. They are a critical component of cell
growth, collagen synthesis, wound healing, and more. The body also uses GAGs to lubricate joints and cushion
them from shock.
Potential Benefits of Chondroitin Sulfate
Chondroitin is a slow-acting supplement that accumulates in the joints over time. Studies found most
participants noticed improvements in their joint health after taking chondroitin supplements for 4-8 weeks.
Chondroitin Supplements for Joint Support
The most notable use of chondroitin supplement is for joint health. Joint pain is a prevalent problem that
worsens with age. Cartilage thins and loses its resiliency as the body ages. Joints become inflamed, stiff,
and painful without this cushion to act as a shock absorber.
Chondroitin is one of the primary building blocks of cartilage, and it helps promote the synthesis of other
cartilage compounds. Increasing the availability of these compounds helps to reduce cartilage breakdown.
Chondroitin sulfate also helps cartilage resist compression, which improves joint mobility and flexibility.
Chondroitin sulfate may also provide joint pain relief due to its anti-inflammatory properties. Reducing
joint inflammation may relieve pressure and pain symptoms while simultaneously improving joint performance.
Chondroitin and Glucosamine
Methylsulfonylmethane (MSM) Synergy
The combination of chondroitin and glucosamine also synergizes with MSM. MSM is another potent
anti-inflammatory that helps reduce free radical damage, repair connective tissues, and support joint
Many individuals opt to take chondroitin and glucosamine together as they synthesize to
maximize joint health benefits. Glucosamine is another cartilage-synthesizing compound that may improve
joint function and reduce joint pain. Where chondroitin reduces cartilage breakdown, glucosamine slows
collagen degradation. Taking chondroitin and glucosamine further enhances both supplements’
Potential Side Effects of Chondroitin Sulfate
Most individuals do not experience any problems when taking chondroitin supplements. Some individuals may
experience mild stomach discomfort (e.g., nausea, bloating, and constipation).
Chondroitin is a natural anticoagulant that may interact with certain medications. Individuals with blood
disorders, taking blood thinners, or taking aspirin should consult a physician before starting chondroitin
How to Store Chondroitin Supplements
Keep chondroitin supplements in a cool, dry area away from sunlight. To maximize the shelf life of
chondroitin, reseal the product after each use.
Bioavailability, Mixing, and Solubility of Chondroitin Sulfate
Chondroitin supplements readily dissolve in water and have a high bioavailability. Individuals can take
chondroitin with or without meals. However, taking chondroitin supplements with food may reduce the
likelihood of stomach discomfort.
Purity and Concentration of Chondroitin Sulfate
PureBulk's chondroitin sulfate powder is extracted from bovine trachea cartilage and is assayed by the
manufacturer to contain at least 90% chondroitin sulfate. The remaining 10% is collagen material from the
extraction process. There are no additives, fillers, or anti-caking agents.
Tested by Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity
and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.