Thiamine HCl (Vitamin B1)



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Supplement Facts & Directions

Supplement Facts

Serving Size: 100 milligrams
Servings Per Container: Varies
Amount Per Serving % Daily Value*
Thiamine (Vitamin B1) (as Thiamine HCI) 89 mg 5933%

* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡ These supplement facts may vary from the product you receive.    Please call for exact numbers.

Other Ingredients: None


Free of:  Added Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives.

Directions:  As a dietary supplement, take 100 mg daily or as directed by a physician. An accurate gram weight scale is recommended.

Warning: If you are pregnant, nursing, taking any medications, or have any medical conditions consult your physician before use. Keep out of reach of children.

Product Details

Thiamine HCl (vitamin B1) is a water-soluble essential nutrient that all bodily tissues need to function. Thiamine has the designation as vitamin B1 because it was the first B vitamin that scientists discovered. It is necessary to generate adenosine triphosphate (ATP) molecules. These molecules are responsible for transferring energy between cells. It is also a cofactor for several enzymes that help metabolize glucose, amino acids, and lipids.

Potential Thiamine Benefits

Vitamin B1 aids several metabolic functions in the body. It is a cofactor to pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase, two enzymes that help generate ATP. ATP is the primary source of energy for cells, which the body can store or use as needed. Thiamine also helps convert carbohydrates into glucose, another significant source of energy for the body.

It’s also a cofactor to several enzymes that help metabolize carbohydrates, including transketolase and branched-chain α-keto acid dehydrogenase. Pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase are also critical for carbohydrate metabolism. Many of these enzymes also help metabolize glucose and amino acids. Thiamine contributes to the breakdown of proteins and fats as well. It also aids digestion by contributing to hydrochloric acid production.

Thiamine is integral to a healthy immune system, as it helps strengthen the body’s ability to endure stressful environments and situations. Thiamine deficiency causes inflammation and decreases how well the immune system functions.

Thiamine is integral to a healthy immune system, as it helps strengthen the body’s ability to endure stressful environments and situations. Thiamine deficiency causes inflammation and decreases how well the immune system functions.

What Causes Thiamine Deficiency?

Thiamine deficiency can occur for several reasons. The most common risk factors include:

  • Drinking a lot of coffee or tea, including decaf
  • Frequently eating raw fish and shellfish
  • Aging
  • Weight loss surgery
  • Having diabetes
  • Eating disorders
  • Dialysis
  • A diet high in rice or grains that lack thiamine
  • High doses of diuretics
  • Lon-term alcohol misuse
  • Conditions that prevent the absorption or cause excess excretion of thiamine

Thiamine Deficiency Symptoms

Identifying a thiamine deficiency can be challenging, as many of the symptoms are unspecific or appear similar to other health concerns. The following are some of the signs of a thiamine deficiency:

  • Loss of appetite. Thiamine sends signals to the brain to indicate hunger and fullness. Insufficient thiamine can disrupt this process and cause individuals to feel full even when they’re not. Not eating enough can lead to other nutrient deficiencies as well, as the individual isn’t consuming enough from food. A sudden loss of appetite is one of the earliest indicators of a thiamine deficiency.
  • Unintentional weight loss. Not feeling hungry can cause unintentional weight loss. Losing weight without meaning to can cause several health problems, particularly if the individual drops below a healthy weight.
  • Neuropathy. Neuropathy secondary to a thiamine deficiency was the first deficiency syndrome identified in humans. It is also the most recognized symptom of a thiamine deficiency. It can present as tingling in the extremities, loss of coordination, and desensitized hands and feet. It typically starts as a pins and needles sensation before more severe neuropathy symptoms begin.
  • Fatigue. A thiamine deficiency can cause excessive tiredness within a few weeks from the onset. Thiamine plays a critical role in energy production. When the body has less thiamine to work with, it doesn’t have enough energy to perform all its functions well.
  • Cognitive problems. Thiamine deficiency can cause confusion and brain fog. It can also make it difficult to think clearly. Severe deficiencies can cause hallucinations and memory loss.

Potential Thiamine Side Effects

Thiamine is water-soluble, and the body excretes any excess it does not need. However, individuals with a thiamine sensitivity may experience flushing, nausea, itching, or hives. Individuals should consult with a doctor before taking any new supplements.


  2. Butterworth RF (2006). "Thiamin". In Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ (eds.).

Tested by Accredited 3rd Party Labs

PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.

*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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