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N-Acetyl L-Cysteine (NAC)



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Supplement Facts & Directions

Supplement Facts

Serving Size: 750 milligrams
Servings Per Container: Varies
Amount Per Serving % Daily Value*
N-Acetyl L-Cysteine 750 mg

* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡ These supplement facts may vary from the product you receive. Please call for exact numbers.

Other Ingredients: None


Free of: Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives.

Directions: As a dietary supplement, take 750 mg (3/16 tsp) up to two times daily, or as directed by a physician. Accurate gram weight scale recommended.

Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. DO NOT use with heart medications. Keep out of reach of children.

Product Details

Sulfur Smell: NAC is a supplement with a characteristic sulfur or egg smell. This is normal. The product has not gone bad.

N-acetyl L-cysteine (also known as NAC and acetylcysteine) is the acetylated form of L-cysteine. L-Cysteine is a semi-essential, sulfur-containing amino acid that is an important structural component in many proteins. 

L-cysteine forms bonds with glutamine and glycine to synthesize glutathione, an antioxidant tripeptide. However, external factors like free radicals, illness, and stress deplete glutathione levels. NAC supplements boost the availability of l-cysteine, which accelerates glutathione production.

Potential Benefits of NAC Supplements

Supplementation of L-cysteine via N-acetyl L-cysteine may support the immune system by improving the availability of glutathione. Glutathione is a powerful antioxidant that scavenges free radicals and activates natural killer cells. When glutathione levels deplete, the body is much more vulnerable to free radical damage. Boosting glutathione levels can help repair this damage.

NAC also reduces the damaging effects of oxidative stress, which may support heart health. NAC may also benefit heart health by improving blood flow and increasing glutathione concentrations in red blood cells.

Did You Know?

NAC synergizes with green tea to reduce the damage caused by oxidized LDL cholesterol.

NAC supplements may support the body’s detoxification process and liver health. Toxic substances often suppress glutathione levels, which NAC may counteract by preserving glutathione availability.

NAC also has anti-inflammatory and expectorant properties. Its ability to reduce inflammation, loosen mucus, and boost glutathione levels may improve lung function. NAC’s anti-inflammatory properties also extend to fat cells, which may help regulate blood sugar.

NAC may provide dermatological benefits as well. NAC accelerates wound healing, which may help acne lesions to resolve faster. NAC may also improve acne healing time by reducing free radicals. NAC may also help restore the skin’s natural barrier and reduce skin inflammation.

When to Take NAC: Morning or Night?

Individuals can take NAC supplements in the morning or at night. However, NAC supplements metabolize into the amino acid l-cysteine. As certain foods can affect amino acid absorption, individuals should take NAC on an empty stomach. Wait at least one hour after eating for maximum absorption. Keep NAC in a cool and dry location to maximize its shelf-life.

Potential NAC Supplement Side Effects

NAC is well-tolerated by most individuals. Excessive doses of NAC may cause nausea, vomiting, constipation, or diarrhea. Individuals taking blood thinners should not take NAC, as it may slow clotting.


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  2. https://jissn.biomedcentral.com/articles/10.1186/1550-2783-2-2-38
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Tested by Accredited 3rd Party Labs

PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.

*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.