REPRESENTATIVE DOCUMENTS
COA
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Supplement Facts & Directions
Supplement Facts
Serving Size: 3000 milligramsServings Per Container: Varies
| Amount Per Serving | % Daily Value* |
|---|---|
| D-Aspartic Acid 3000 mg | † |
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡
These supplement facts may vary from the product you receive. Please call for exact numbers.
Other Ingredients: None
Free of: Added Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives.
Directions: As a dietary supplement, take 2500 to 3000 mg (1/2 Tbsp) once daily, preferably with the first meal of the day or as directed by a physician. DO NOT take more than the suggested serving or longer than eight continuous weeks without at least four weeks off.
Warning: If you are pregnant, nursing, taking any medications, or have any medical conditions consult your physician before use. Not to be used by men under 21 years old. Not to be used by women. This supplement could trigger a failed test from various sports governing agencies. Keep out of reach of children.
Product Details
What is D-Aspartic Acid (DAA)?
Aspartic acid exists in two forms: l-aspartic acid and d-aspartic acid. They are enantiomers, meaning their molecular formulas are mirror images that are not superimposable. The body incorporates l-aspartic acid into proteins. L-Aspartic acid also participates in the urea cycle to eliminate toxic ammonia buildup. D-Aspartic acid plays a role in increasing the release of testosterone-producing hormones, increasing testosterone production, and boosting the release of testosterone into the testes.
Potential D-Aspartic Acid Benefits
Potential D-Aspartic Acid Benefits for Testosterone
D-Aspartic acid acts as a signaling molecule in the neuroendocrine systems in the pituitary gland and the hypothalamus. DAA’s primary function revolves around regulating, releasing, or synthesizing numerous sex hormones. Its actions stimulate the secretion of gonadotropin-releasing hormone, growth hormone, luteinizing hormone, and prolactin.
It also upregulates the messenger RNA (mRNA) involved in producing Stimulating steroidogenic Acute Regulatory Protein (StAR) compounds. StAR controls the production of sex hormones in Leydig cells—the primary source of testosterone in men. One study found that participants taking DAA supplements experienced a 15% increase in testosterone at six days and a 42% increase after 12 days. Another study reported similar findings, with infertile men experiencing a 30-60% testosterone increase after three months.
D-Aspartic Acid and Fertility
D-Aspartic acid stimulates the release of several hormones involved in fertility, such as gonadotropin-releasing hormone. Gonadotropin-releasing hormone directly affects the levels of sex hormones, libido, and fertility. It causes the pituitary gland to produce luteinizing hormone and follicle-stimulating hormone. In men, luteinizing hormone promotes testosterone synthesis and triggers the production and maturation of sperm in the testes. In women, gonadotropin-releasing hormone prompts the ovaries to synthesize estrogen and progesterone, which are necessary for eggs to mature and for eventual ovulation. D-Aspartic acid may support fertility due to its influence on developing and releasing mature sperm and eggs.
D-Aspartic Acid and Cognition
DAA may support cognition and improve memory. It is a neurotransmitter involved in forming new neurons in the brain and learning. Animal studies show that DAA improves synaptic plasticity and cognition. One study noted that animals given DAA supplements had enhanced cognitive capabilities due to DAA’s role in modulating memory and learning. DAA may further enhance cognition by upregulating NMDA receptors—one of two glutamate receptors involved in learning and new memory formation.
Potential D-Aspartic Acid Side Effects
A 90-day study failed to find any d-aspartic acid side effects. That same study performed in-depth blood tests to measure creatinine, electrolytes, glucose, liver enzymes, urea, and both red and white blood cell function. The researchers found no anomalies. Some individuals are sensitive to amino acids and may experience mild stomach discomfort when taking d-aspartic acid supplements.
References
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC353039
- https://www.ncbi.nlm.nih.gov/pubmed/18642934
- https://pubmed.ncbi.nlm.nih.gov/17118457
- https://pubmed.ncbi.nlm.nih.gov/10744627
- https://pubmed.ncbi.nlm.nih.gov/18642934
- https://pubmed.ncbi.nlm.nih.gov/17118457
- https://pubmed.ncbi.nlm.nih.gov/33218144
- https://pubmed.ncbi.nlm.nih.gov/22872108
- https://www.cancer.gov/publications/dictionaries/cancer-terms/def/gonadotropin-releasing-hormone
- https://www.ncbi.nlm.nih.gov/pubmed/19860889
- http://www.scirp.org/journal/PaperInformation.aspx?paperID=24016
- https://pubmed.ncbi.nlm.nih.gov/21163862
- https://pubmed.ncbi.nlm.nih.gov/26707656
- https://pubmed.ncbi.nlm.nih.gov/19890700
- https://www.nature.com/articles/s41598-021-85360-w
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703758
- https://www.ncbi.nlm.nih.gov/books/NBK2532
Tested by Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.