|Amount Per Serving||% Daily Value*|
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡ These supplement facts may vary from the product you receive. Please call for exact numbers.
Other Ingredients: None
Free of: Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives.
Directions: As a dietary supplement, take 400 mg up to three times daily
between meals, or as directed by a physician. Accurate gram weight scale recommended..
Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children. Store in a cool, dark & dry place.
L-tyrosine, or simply tyrosine, is an amino acid required to synthesize several neurotransmitters. Tyrosine hydroxylase enzymes found in dopaminergic cells convert tyrosine into levodopa (L-DOPA), the direct precursor to dopamine. The body converts L-DOPA into the catecholamines (monoamine neurotransmitters) norepinephrine and epinephrine. Although many foods contain dopamine, it’s unable to cross the blood-brain barrier (BBB). The body must synthesize dopamine in the brain from amino acids, and tyrosine is the most common amino acid found in foods.
Tyrosine converts into several other important physiological compounds. The thyroid uses tyrosine to develop triiodothyronine (T3) and thyroxine (T4) hormones, and it’s necessary to create the benzoquinone structure of Coenzyme Q10 (CoQ10). The body also uses tyrosine to synthesize the skin pigment melanin. It is one of the 20 amino acids that cells use to synthesize proteins as well.
Mental stress or situations that require high cognitive demands rapidly deplete catecholamines, particularly dopamine and norepinephrine. As catecholamine levels diminish, cognitive performance suffers. Several human studies have shown that tyrosine supplements help improve working memory, cognitive flexibility, and task switching by replenishing these critical catecholamines. Another study reported that l-tyrosine improves alertness in sleep-deprived individuals, too. Animal studies show l-tyrosine also effectively attenuated the effects of environmental stress on memory, such as cold exposure.
Tyrosine supplements may exert neuroprotective effects in the brain, too. When catecholamines decrease in neuronal tissues, oxidative stress increases. Oxidative stress can lead to numerous adverse health effects, such as premature brain aging and neurodegenerative conditions. Researchers believe tyrosine supplements act as an antioxidant by increasing the availability of the catecholamines L-DOPA, dopamine, and noradrenaline, which may also help scavenge free radicals.
Tyrosine supplements may enhance exercise performance. Physical exercise impairs catecholamine function and leads to mental fatigue. While tyrosine does not exert a direct effect on exercise capacity, it does improve mental performance. For athletes, enhancing cognitive function allows for more successful execution of motor skills and tactics.
Most individuals tolerate tyrosine supplements well. However, it may interact with some medications, including Monoamine Oxidase Inhibitors (MAOIs), L-DOPA, and thyroid medications. Consult with a physician before taking any new supplements.
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.