Supplement Facts
Serving Size: 2 CapsulesServings Per Container: Varies
| Amount Per Serving | % Daily Value* |
|---|---|
| D-Glucosamine HCl (Vegan) 635 mg | † |
| Methylsulfonlymethane (MSM) 635 mg | † |
| Chondroitin Sulfate 300 mg | † |
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡
These supplement facts may vary from the product you receive. Please call for exact numbers.
Other Ingredients: Cellulose Capsule
Free of: Added Sugar, Soy, Dairy, Yeast, Gluten, & Additives.
Directions: As a dietary supplement, take two capsules daily with water or as directed by a physician. Taking it with meals may improve gastrointestinal tolerance.
Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children.
Tested By Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Supplements for Joint Health
Healthy joints rely on the integrity of cartilage, synovial fluid, and connective tissue to allow smooth movement and absorb mechanical stress. Over time, aging, repetitive movement, physical activity, and inflammation can contribute to cartilage breakdown, stiffness, and reduced mobility.
Researchers have studied nutritional compounds involved in cartilage structure and sulfur metabolism for their role in maintaining joint comfort and function. Advanced Joint Support combines three highly researched joint-support ingredients—vegan D-glucosamine hydrochloride (HCl), chondroitin sulfate, and methylsulfonylmethane (MSM)— into a single, synergistic formula to help support the structural and biochemical needs of healthy joints.
Potential Advanced Joint Support Benefits
Supports Cartilage Structure and Integrity
Glucosamine is a naturally occurring amino sugar involved in synthesizing glycosaminoglycans and
proteoglycans—critical structural components of cartilage and synovial fluid. Vegan D-glucosamine HCl provides a
non-shellfish, highly bioavailable form of glucosamine that supports cartilage synthesis and connective tissue
maintenance.
Chondroitin sulfate is a major component of cartilage that helps retain water within the cartilage matrix, allowing joints to resist compression and mechanical load better. Together, glucosamine and chondroitin help support the structural framework that cushions joints during daily movement and physical activity.
Promotes Joint Comfort and Mobility
MSM is a naturally occurring sulfur-containing compound that provides bioavailable sulfur for connective tissue,
collagen, and cartilage formation. Research shows that MSM may support joint comfort and physical function,
particularly in individuals experiencing stiffness related to exercise, aging, or repetitive use. When used
together, glucosamine, chondroitin, and MSM support joint mobility, flexibility, and overall comfort with
consistent use.
Supports Connective Tissue and Collagen Formation
Sulfur is essential for synthesizing collagen and other structural proteins found in ligaments, tendons, and
cartilage. MSM supplies sulfur, while glucosamine and chondroitin provide structural precursors that support the
integrity and resilience of connective tissue.
Encourages Long-Term Joint Function Proactive support is best for lasting joint health. Rather than acting as a short-term solution, this blend helps maintain joint structure and function over time, making it suitable for individuals seeking ongoing joint support.
Glucosamine and chondroitin provide the building blocks for cartilage, helping it retain moisture and maintain the cushioning needed to withstand everyday mechanical stress. At the same time, MSM supplies bioavailable sulfur that supports collagen formation in ligaments and tendons, helping to regulate inflammatory processes linked to stiffness and discomfort. Employing a multi-faceted approach supports a healthier joint environment overall, promoting lasting mobility, comfort, and flexibility.
Potential Advanced Joint Support Side Effects
Most individuals tolerate Advanced Joint Support well when taken as directed. Some may experience mild gastrointestinal effects, such as bloating, nausea, or loose stools, particularly during initial use.
Because this formula uses vegan glucosamine HCl, it is suitable for individuals avoiding shellfish-derived ingredients. Individuals who are pregnant, nursing, taking anticoagulant medications, or managing chronic joint conditions should consult a qualified healthcare professional before use.
References
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6035477
- https://pubmed.ncbi.nlm.nih.gov/17353133
- https://pubmed.ncbi.nlm.nih.gov/7575762
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3150191
- https://pubmed.ncbi.nlm.nih.gov/17516722
- https://pmc.ncbi.nlm.nih.gov/articles/PMC12250884
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5372953
- https://pubmed.ncbi.nlm.nih.gov/40647198
- https://pubmed.ncbi.nlm.nih.gov/25461402
- https://pubmed.ncbi.nlm.nih.gov/22525653
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4502733
- https://pubmed.ncbi.nlm.nih.gov/22525653
- https://pubmed.ncbi.nlm.nih.gov/28790224
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8180127


