Note: This product is concentrated Cyanocobalamin (not for individual use). However, we do offer a 1% Cyanocobalamin and 99% Mannitol blended product as well.
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What is Vitamin B12?
Vitamin B12 is a water-soluble essential B vitamin that contains the mineral Cobalt. Vitamin B12 is a cofactor for several enzymes that are critical for several metabolic processes, including methionine synthase and l-methyl-malonyl-CoA mutase. Vitamin B12 is also essential for energy production and DNA synthesis.
The body can’t produce vitamin B12, so individuals obtain it through food and supplements. Most vitamin B12-rich foods come from animals, such as eggs, meats, and milk. As a result, vegans may struggle to meet their B12 dietary needs without supplementation.
Vegan Vitamin B12
PureBulk’s pure cyanocobalamin powder is a semi-synthetic form of vitamin B12 derived from bacterial fermentation that is safe for vegans and vegetarians.
What is Cyanocobalamin?
B12 is a member of the cobalt-containing compounds collectively known as cobalamins. Cobalamin vitamers have similar chemical structures that exert B12 vitamin activity when the body is in a B12-deficient state. Cobalamin exists in several forms, including cyanocobalamin, hydroxocobalamin, methylcobalamin, and adenosylcobalamin.
Cyanocobalamin forms when a cyanide molecule replaces the adenosyl ligand in vitamin B12. Cyanocobalamin is the most common form of vitamin B12, as it is the most stable. Once ingested, it converts into one of the active forms of vitamin B12, adenosylcobalamin or methylcobalamin.
Potential Benefits of Vitamin B12 Supplement Powder
Cyanocobalamin plays a pivotal role in red blood cell production. Low vitamin B12 can cause the malformation of red blood cells, making them bloated and oval-shaped rather than small and round. Oddly shaped red blood cells have difficulty entering the bloodstream and transporting oxygen to the organs. Without sufficient blood cells, the body is prone to fatigue and weakness.
Vitamin B12 supplements may support strong bones as well. Adults that don’t have sufficient B12 levels experience lower than normal bone density, an effect that is particularly prominent in women. Over time, bones can become fragile and weak.
Like most B vitamins, cyanocobalamin supports energy production. While vitamin B12 doesn’t innately provide energy, it’s a cofactor for energy-producing enzymes and supports energy metabolism.
Cognitive health relies on sufficient levels of vitamin B12. Low vitamin B12 levels can reduce the synthesis of methionine and S-adenosylmethionine (SAM), which are essential for methylation reactions. These reactions play a significant role in synthesizing components of the myelin sheath and neurotransmitters.
Vitamin B12 supplements have several other interesting properties that may help balance moods, support heart health, and promote eye health.
What Causes B12 Deficiency?
B12 insufficiency and deficiency are prevalent problems across the globe. Up to 20% of adults over the age of 60 in the US and UK have insufficient vitamin B12 levels, while 6% have a true B12 deficiency. Certain groups are more likely to experience a B12 deficiency, including the elderly, people with gastrointestinal disorders, individuals taking proton pump inhibitors, and vegans. Certain autoimmune conditions can affect B12 absorption as well.
Vitamin B12 Deficiency symptoms
The following are several signs that may indicate a B12 insufficiency or deficiency:
Fatigue. Fatigue is often the earliest symptom of low vitamin B12 levels due to B12’s role in red blood cell formation and energy production.
Pale skin. B12 deficiency can affect the formation of red blood cells. A lack of properly developed red blood cells can make the skin look pale. B12 deficiency can also cause a yellowing of the skin and eyes.
Headaches. Headaches are one of the most common symptoms of B12 deficiency in both children and adults.
Problems concentrating. B12 deficiency can exert negative effects on the central nervous system. The elderly have a higher risk of experiencing this symptom, as the likelihood of a B12 deficiency increases with age.
Oral health problems. B12 deficiency can present as several problems in the mouth, such as sores, ulcers, or an inflamed and painful tongue.
Paranesthesia in the extremities. Individuals with low B12 levels are more likely to experience a burning, tingling, or pins-and-needles sensation in the hands and feet.
Potential Side Effects of Vitamin B12 Supplement Powder
As an essential vitamin, individuals typically tolerate vitamin B12 well. As a water-soluble vitamin, the body excretes any excess B12 that it doesn’t need. However, taking excessively large doses can cause headaches, nausea, tingling sensations, weakness, or diarrhea.
Tested by Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.