PureBulk, Inc.
NMN + Resveratrol (95% Piperine)
Supplement Facts
Serving Size: 2 CapsulesServings Per Container: Varies
| Amount Per Serving | % Daily Value* |
|---|---|
| NMN (beta-nicotinamide mononucleotide) 500 mg | † |
| Resveratrol (Polygonum cuspidatum) (Root) 500 mg | † |
| Piperine (from Black Pepper Extract) | 5 mg |
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡
These supplement facts may vary from the product you receive. Please call for exact numbers.
Other Ingredients: Cellulose Capsule
Free of: Added Sugar, Soy, Dairy, Yeast, Gluten, Corn, & Additives.
Directions: As a dietary supplement, take two capsules daily or as directed by a physician.
Warning: If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before use. Individuals with diabetes, bleeding disorders, or gastrointestinal issues should seek medical advice prior to use. Piperine may interact with certain medications. Do not use if you have Hepatitis C or are taking antiviral drugs. Keep out of reach of children.
Tested By Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
What is NMN?
Nicotinamide mononucleotide (NMN) is a naturally occurring compound and direct precursor to NAD+ (nicotinamide adenine dinucleotide), a critical coenzyme in energy metabolism. NAD+ is essential for converting nutrients into cellular energy (ATP), supporting DNA repair, and regulating enzymes called sirtuins that influence cellular health and longevity.
NAD+ levels naturally decline with age, contributing to fatigue, decreased metabolic efficiency, and reduced resilience to cellular stress. Taking NMN supplements can help restore NAD+ levels, promoting energy, metabolic balance, and age-related cellular maintenance.
What is Resveratrol?
Resveratrol is a naturally occurring polyphenol found in foods like red grapes, berries, and peanuts. It is known for its antioxidant properties and its ability to activate sirtuins, which help regulate longevity pathways, stress responses, and cellular repair mechanisms.
Pairing NMN with resveratrol enhances their abilities to activate sirtuins, as NMN provides the necessary NAD+ to fuel sirtuin activation. It is a synergistic combination that supports cellular energy, metabolic function, and longevity.
What is Piperine?
Piperine is the active compound in black pepper that enhances the absorption of certain nutrients, including polyphenols like resveratrol. In this formula, piperine 95% enhances the bioavailability of NMN and resveratrol, allowing the body to utilize these compounds more effectively.
Potential NMN + Resveratrol Benefits
- Boosts NAD+ Levels & Cellular Energy: NMN is a direct precursor to NAD+, a critical coenzyme found in every living cell that declines with age. By replenishing these levels, the duo supports mitochondrial efficiency and the production of ATP, providing the essential fuel required for cellular energy throughout the body.
- Activates Longevity Pathways: Combining NMN and resveratrol creates a synergistic fueling effect, where resveratrol activates sirtuins—proteins responsible for cellular health—while NMN provides the NAD+ they need to function optimally. Their synergy enhances DNA repair mechanisms and strengthens the body's resilience against environmental stressors.
- Supports Metabolic Health: These compounds help mimic the biological effects of exercise and calorie restriction by activating the AMPK pathway, leading to enhanced insulin sensitivity, improved glucose metabolism, and a more balanced approach to energy storage and utilization.
- Promotes Cognitive Function: NMN and resveratrol support sharper focus and memory retention by improving blood flow to the brain and protecting neurons from age-related decay. They may also help maintain neuroplasticity, which is vital for learning and long-term mental clarity.
- Antioxidant Protection: Resveratrol acts as a potent antioxidant, neutralizing free radicals, while NMN supports the cellular environment necessary for natural defense systems. Together, they significantly reduce oxidative stress, preventing the biological rusting that damages cellular integrity over time.
- Supports Cardiovascular Health: NMN and resveratrol promote nitric oxide production, which helps relax and dilate blood vessels for better circulation. By improving endothelial function and reducing arterial stiffness, the combination supports overall heart vigor and helps maintain healthy vascular pressure.
- Potential Anti-Aging Effects: Beyond simply living longer, these supplements aim to extend healthspan by promoting physical vitality and recovery. They help the body retain its youthful resilience and functional strength by maintaining the epigenome and slowing cellular senescence.
Potential NMN + Resveratrol Side Effects
Most individuals tolerate NMN and resveratrol well. Some people may experience:
- Mild digestive discomfort (nausea, bloating)
- Headache or dizziness in sensitive individuals
- Temporary flushing or warmth
References
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7963035
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3123408
- https://www.sciencedirect.com/science/article/pii/S221345302300188X
- https://www.cell.com/trends/cell-biology/abstract/S0962-8924(14)00063-4, https://www.cell.com/cell-metabolism/fulltext/S1550-4131(17)30670-8
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7238909
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10917541
- https://pmc.ncbi.nlm.nih.gov/articles/PMC12152427
- https://www.mdpi.com/2072-6643/11/1/143
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3462230
- https://www.pnas.org/doi/10.1073/pnas.0610068104
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3880862
- https://www.sciencedirect.com/science/article/pii/S2405580823000572
- https://pubmed.ncbi.nlm.nih.gov/27130898
- https://www.sciencedirect.com/science/article/pii/S0925443914002920
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6657254
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4994441
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7587336
- https://www.sciencedirect.com/science/article/pii/S2772753X2300360X
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11473484
- https://pubmed.ncbi.nlm.nih.gov/39832074, https://www.mdpi.com/1422-0067/20/9/2155
- https://www.sciencedirect.com/science/article/abs/pii/S1089860322001136
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8466271
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4854911
- https://www.mdpi.com/1422-0067/25/17/9526
- https://www.sciencedirect.com/science/article/pii/S2589004224028839


