PureBulk, Inc.
Tremella Mushroom Extract (Snow Fungus)
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Supplement Facts
Serving Size: 1/4 tsp (1g)Servings Per Container: Varies
| Amount Per Serving | % Daily Value* |
|---|---|
| Tremella Mushroom Extract (Tremella fuciformis) (Fruiting Body) 1000 mg | † |
| (Standardized to ≥40% Polysaccharides) |
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡
These supplement facts may vary from the product you receive. Please call for exact numbers.
Other Ingredients: Maltodextrin
Free of: Added Sugar, Dairy, Soy, Wheat, and Yeast.
Directions: As a dietary supplement, take 1g (1/4 tsp) daily with water or a beverage of your choice, or as directed by a physician.
Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children.
Tested By Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
What is Tremella Mushroom (Snow Fungus)?
Tremella mushroom (Tremella fuciformis), commonly called snow fungus or white jelly mushroom, is a distinctive, pale, translucent fungus that grows on the dead branches of deciduous trees across tropical and subtropical regions of Asia, Australia, and the Americas. It has featured in traditional Chinese remedies and culinary traditions for more than 2,000 years as a therapeutic mushroom and a beauty food. According to historical accounts, Yang Guifei, one of the four great beauties of ancient China, attributed her luminous complexion in part to regularly consuming snow fungus.
The mushroom’s biological activity is primarily driven by its acidic heteropolysaccharides, a class of complex carbohydrate structures with exceptionally high water-binding capacity and diverse immunological properties. These polysaccharides, sometimes referred to as Tremella polysaccharides (TPS), have garnered substantial scientific interest due to their effects on skin hydration, inflammation, neurology, and immune function.
Potential Tremella Mushroom Benefits
Exceptional Skin Hydration
Tremella polysaccharides are hygroscopic, meaning they attract and retain water, and have been compared to hyaluronic acid in their moisture-binding capacity. Research suggests that the molecular weight of Tremella polysaccharides may allow for better dermal penetration than conventional hyaluronic acid, making them particularly effective as an endogenous hydration support when ingested. In vitro and animal studies have demonstrated measurable increases in skin water content, improved epidermal barrier function, and upregulation of aquaporin channels following exposure to Tremella extract.
Anti-Inflammatory Effects
Tremella mushrooms have demonstrated anti-inflammatory activity in several preclinical models. TPS suppresses the production of pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-6, and inhibits NF-κB signaling—a central inflammatory pathway implicated in numerous chronic conditions. These anti-inflammatory mechanisms may contribute to its observed benefits across multiple organ systems, from the skin to the gut and nervous system.
Antioxidant Protection
In addition to its anti-inflammatory effects, Tremella extract has shown significant antioxidant capacity in multiple studies. TPS has demonstrated the ability to scavenge free radicals, elevate superoxide dismutase (SOD) activity, and reduce malondialdehyde (MDA) levels—a biomarker of lipid peroxidation and oxidative stress. These antioxidant properties complement its skin health benefits and contribute to broader systemic protection against oxidative damage.
Neuroprotection and Cognitive Support
Emerging research shows that Tremella has neuroprotective properties that parallel those of lion’s mane. Studies reported that TPS may stimulate nerve growth factor (NGF) synthesis, protect neurons from amyloid-beta-induced toxicity, and attenuate age-related cognitive decline in animal models. These findings suggest potential applications in supporting long-term brain health, though human clinical trials are still in early stages.
Immune Modulation
Like many therapeutic mushroom polysaccharides, TPS has shown immunomodulatory activity. Research has demonstrated its ability to enhance macrophage activity, stimulate NK cell function, and modulate cytokine production. These actions collectively strengthen the body’s innate immune response, creating a more robust defense against pathogens and cellular abnormalities.
Wound Healing Support
Several preclinical studies have shown that Tremella polysaccharides have wound-healing properties. Researchers attribute this to their ability to promote keratinocyte migration, fibroblast proliferation, and collagen synthesis. These processes are fundamental to healthy tissue repair, and the data suggests that Tremella extract may support post-injury healing and skin regeneration.
Potential Tremella Mushroom Side Effects
Tremella mushrooms are a common culinary food across East and Southeast Asia and are generally regarded as safe for long-term use in healthy adults. Adverse effects are rarely reported. As with other mushroom extracts, individuals with known mushroom sensitivities or fungal allergies should exercise appropriate caution.
Given its immunomodulatory properties, individuals with autoimmune conditions or those on immunosuppressive therapies should consult a healthcare provider before incorporating Tremella into their supplement regimen.
References
- https://pmc.ncbi.nlm.nih.gov/articles/PMC12027390
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8172338
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.944801/full
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6696028
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6682156
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5954968
- https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.648162/full
- https://pubmed.ncbi.nlm.nih.gov/36757441
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8049506
- https://iadns.onlinelibrary.wiley.com/doi/full/10.1002/fft2.70200
- https://link.springer.com/article/10.1007/s44462-025-00039-z
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8172338
- https://www.sciencedirect.com/science/article/pii/S2772566925000448
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3763079
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3763589
- https://www.sciencedirect.com/science/article/pii/S0753332225011606
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11901780
- https://pubmed.ncbi.nlm.nih.gov/29319408
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10970926
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10220659
- https://advances.umw.edu.pl/en/article/2024/33/5/533
- https://pmc.ncbi.nlm.nih.gov/articles/PMC12615138
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8931924
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9946334


