Combat Stress and Fatigue with Supplements
December 05, 2023
Stress and fatigue are all too familiar companions for many individuals. Whether it's due to work pressures, personal
responsibilities, or the challenges of maintaining a healthy lifestyle, the toll of stress and fatigue on our
overall well-being is undeniable. Fortunately, several strategies can help combat these common adversaries,
including exercise, meditation, unwinding with a good book, or spending time with friends. Sometimes, however, these
go-to stress relievers can fall short of expectations, leaving you tired and tense. For many, supplements can be the
transformative element that enables them to manage their stress and fatigue better, boost resilience, and foster a
healthier, more balanced lifestyle.
Ashwagandha for stress relief.
Ashwagandha is an adaptogenic herb that helps the body adapt to and resist the effects of stress. Adaptogens
modulate the body's stress response by influencing stress hormone production (cortisol) and supporting overall
adrenal function. Several studies reported that participants taking ashwagandha supplements experienced significant
improvements in stress scores and sleep quality compared to the placebo groups. By incorporating adaptogens like
ashwagandha into your daily routine, you may find a natural and holistic approach to managing stress and fatigue. [1
- 6]
L-Theanine to promote relaxation without
sedation.
L-Theanine is an amino acid found in tea leaves, particularly in green tea. Known for its calming effects,
L-Theanine promotes relaxation without inducing drowsiness. L-theanine works by increasing alpha brain waves to
promote wakeful relaxation, increasing neurotransmitters associated with relaxation, and blocking excitatory
neurotransmitters that contribute to feelings of stress. Supplementing with L-Theanine can be an effective strategy
to manage stress and achieve a state of focused calm. [7 - 14]
Melatonin to improve sleep quality and calm the central nervous system.
Adequate and quality sleep is crucial for overall well-being, and disruptions in sleep patterns can
contribute to increased stress levels. By promoting better sleep, melatonin indirectly supports stress management.
While most individuals take melatonin to regulate their sleep-wake cycle, its potential benefits extend beyond
sleep. It acts on specific receptors in the brain that regulate stress to help induce a relaxed state. Taking a
combination of melatonin and l-theanine can enhance sleep quality and relaxation immensely. [15 - 21]
Bacopa monnieri to soothe mental stress and improve
mood.
Bacopa Monnieri, also referred to as Brahmi, is another adaptogenic herb that Ayurvedic cultures have used for
centuries to enhance cognition and relieve stress. Cortisol production is an essential stress response, but
chronically elevated cortisol can have detrimental health effects. Bacopa is rich in a class of compounds known as
bacosides that help regulate cortisol for a more adaptive stress response. Bacopa monnieri also influences serotonin
and dopamine in the brain. These neurotransmitters are essential for mood regulation. By modulating their levels,
Bacopa may have a calming effect. [22 - 33]
Omega-3 fatty acids to reduce inflammation and improve stress
resilience.
Omega-3 fatty acids, commonly found in fish oil capsules and certain seeds, have potent anti-inflammatory
properties. Chronic stress can contribute to inflammation, affecting both physical and mental well-being. In
addition to reducing inflammation, omega-3s also improve stress resilience. One study found that omega-3s helped
participants resist the damaging effects of stress better than the placebo group. Omega-3s help regulate
inflammation, provide support for a healthy response to stress, and promote overall cognitive function. Another
study supported these findings, showing that omega-3 supplementation prevented stress-induced adrenal activation,
leading to reduced epinephrine and cortisol secretion. [34 - 36]
B vitamins to energize
the body and mind.
The B-vitamins, including B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7
(biotin), B9 (folic acid), and B12 (cyanocobalamin), are crucial for energy metabolism and synthesizing
neurotransmitters that influence mood. Deficiencies in these vitamins can contribute to feelings of fatigue and
mental fog. The body needs B vitamins to maintain a healthy stress response. They can also improve energy and mood
by lowering homocysteine levels. Additionally, B vitamins provide fuel for the neurotransmitters that help relieve
stress, such as GABA and acetylcholine. [37 - 42]
Magnesium to help you unwind and relax.
Magnesium is an essential mineral involved in hundreds of biochemical reactions in the body, including those related
to stress management, relaxation, and mood regulation. Stress, particularly chronic stress, can increase magnesium
excretion through urine. The body may release more magnesium as part of the stress response, contributing to lower
magnesium levels over time. Unfortunately, the physiological responses to stress, such as muscle tension and
increased heart rate, cause a higher demand for magnesium. The result is a vicious cycle that reduces stress
tolerance by continually depleting magnesium while increasing the need for it. Supplementing with magnesium can
potentially alleviate stress symptoms for better relaxation. [43 - 49]
Stress can stem from various sources, ranging from job-related pressures to financial, health, or relationship
challenges. Fortunately, several vitamins and supplements can help alleviate stress. Supplements like ashwagandha,
l-theanine, melatonin, and magnesium provide relief from stress symptoms, while B complex vitamins, bacopa monnieri,
and omega-3 fatty acids enhance the body's resilience against life's stressors. Incorporating these supplements into
a balanced lifestyle may contribute to a more comprehensive approach to stress management, promoting mental and
physical well-being.
Research and References
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https://health.clevelandclinic.org/what-is-ashwagandha
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252722
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270108
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456824
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788115
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435669
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746283
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- https://pubmed.ncbi.nlm.nih.gov/23772955
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436272
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696156
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538287
-
https://www.nature.com/articles/s41380-021-01077-2
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290459
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316433
- https://www.ncbi.nlm.nih.gov/pubmed/21905094
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- https://pubmed.ncbi.nlm.nih.gov/7836621
- https://www.mdpi.com/2072-6643/9/5/429
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352515