What is Cholecalciferol (Vitamin D3)?
Vitamin D3, otherwise known as cholecalciferol, is a pro-hormone and fat-soluble nutrient produced in the skin. It is a seco-steroid hormone that regulates calcium homeostasis and balance within the body. It is an essential vitamin and one of 24 critical micronutrients the body needs to survive.
Vitamin D is known as the "sunshine vitamin" because the skin can produce it photochemically from sunlight or ultraviolet light. Vitamin D formed in this manner is called "natural vitamin D" or vitamin D3. Sun exposure for just 15 minutes daily can provide 2,000 to 5,000 IU of vitamin D. Individuals are at a greater risk of vitamin D3 deficiency during the winter, as they tend to spend more time indoors. They’re likely only exposing their hands and face to sunlight as well, which dramatically reduces the body’s ability to produce vitamin D from sunlight. Wearing sunscreen also inhibits vitamin D3 absorption.
Difference Between Vitamin D2 and D3
Vitamins D exists in two forms, D2 and D3. Vitamin D2, ergocalciferol, is derived from fortified milk, herring, mackerel, tuna, salmon, sardines, eggs, fortified cereals, and baked goods. Vitamin D3, cholecalciferol, is the preferable form as it has better bioavailability and efficacy. Some food sources of vitamin D3 include cod liver oil, salmon, and tuna. However, individuals would have to consume these foods almost daily to meet their vitamin D needs via food sources.
Potential Vitamin D3 Benefits
Vitamin D is best known for its role in the development and maintenance of healthy teeth, bones, and cartilage. Vitamin D helps strengthen bones and teeth by improving the absorption of calcium and phosphorus from the small intestine. Vitamin D also affects parathyroid hormone, which regulates bone turnover and release of calcium from bone. Vitamin D3 also reduces the risk of falls and bone fractures.
Vitamin D deficiency can lead to serious effects. Children without adequate vitamin D are more susceptible to developing rickets, a disease characterized by deformation of bones and teeth. Adults with insufficient amounts of vitamin D have an increased risk of developing osteomalacia (similar to rickets) and are more likely to suffer from osteoporosis, a bone-weakening disease.
Other potential vitamin D3 benefits include boosting mood, improving strength in the upper and lower body, and improving longevity.
Optimize Vitamin D and K2
Vitamins and minerals often interact with other nutrients. Some depend on each other to work, while others may deplete certain nutrients. Fat-soluble vitamins work in tandem, and it's a good idea to ensure you’re consuming enough vitamin K2. PureBulk carries vitamin D and K2 capsules.
Calcium and Vitamin D Supplement
Vitamin D promotes and enhances calcium and magnesium absorption, the two essential minerals necessary for strong bones. The body also requires vitamin D3 to utilize phosphorus and to absorb and metabolize vitamin A.
By increasing GI absorption of phosphorus and calcium, cholecalciferol increases serum calcium concentrations. As a result, osteoclastic resorption and distal renal tubular reabsorption of calcium increase, and optimal levels are required to ensure proper bone mineral density and serum (blood) calcium levels.
Potential Side Effects of Vitamin D3 (Cholecalciferol)
Like other fat-soluble vitamins, vitamin D can be toxic when consumed in excessive amounts. Body tissues store excess vitamin D and may lead to hypercalcemia and excess bone loss. Individuals at particular risk include those with hyperparathyroidism, kidney disease, sarcoidosis, tuberculosis, or histoplasmosis.
Symptoms of too much vitamin D include nausea, weakness, constipation, irregular heartbeat, weight loss, seizures, and irritability.
Solubility and Suggested Preparation of Vitamin D3 (Cholecalciferol)
Vitamin D3 is an oil-soluble vitamin; however, it’s important to note that the carriers for this vitamin are water-soluble. For individuals interested in manufacturing standalone tinctures or mixing vitamin D3 with additional fat-soluble vitamins, this should not present a problem. These individuals will need to filter their final tincture, though. Because the carriers are water-soluble, they won’t dissolve into an oil base. To rid tinctures of the water-soluble particulates, these individuals can filter or decant the oil from the undissolved materials.
Vitamin D3 is most effective when taken at mealtimes, preferably with fatty foods.
How Should I Store It?
PureBulk packages vitamin D3 supplement powder in a resealable bag. Store it in a cool, dry area protected from light. Reseal after each use.
Purity and Concentration of Vitamin D3 (Cholecalciferol)
This PureBulk Vitamin D3 (cholecalciferol) powder has a concentration of at least 100,000 IU/gram. (IU refers to International Units, a standard of measurement regarding the amount of the vitamin.)
References & Further Research
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