What is Choline Bitartrate?
Choline bitartrate is a water-soluble nutrient often included in the B vitamin category and categorized as a
lipotropic compound (Wikipedia).
Lipotropic compounds (lipotropes) support the liver by converting transported fat into energy. Choline is
coupled with bitartrate (tartaric acid) in this dietary supplement to improve its absorption rate within the
human body. This supplement helps synthesize compounds essential for the health of cell membranes. Small
amounts of choline are produced in the human body, but these natural quantities are often insufficient.
Choline (especially in lecithin form) is a basic dietary component present
in many fat and protein-containing foods. Organ meats, eggs, legumes, wheat germ and peanuts are all
excellent natural sources of choline. Choline is usually found in the phospholipids (fat portion) of the
cell membrane as phosphatidylcholine (lecithin) and in the covering of nerve fibers (myelin sheath); it is
believed to influence muscle contractions, coordination and movement.
Aside from its lipotrophic properties, choline works with the central nervous system to regulate nerve
impulse transmissions, cell communications and muscle functioning. Choline helps produce the
neurotransmitter acetylcholine (Wikipedia), which plays a role in appetite, behavior, memory and mood. Choline also
has antioxidant properties that protect cells.
Choline is an essential nutrient required by the body for fat and cholesterol emulsification and
transportation and the production of hormones. It also is used for gallbladder and liver function and
central nervous system regulation.
While not technically a B vitamin, it is often included in the B vitamin complex because it works intimately
with other B vitamins, particularly folic acid (vitamin B9) and cyanocobalamin (vitamin B12) to keep the
Choline bitartrate helps produce lipotropic agents that convert fat into useful products and aid in the
production of HDL cholesterol. A major use of choline in the body is the formation of betaine, an important methyl donor.
Choline bitartrate increases the mobilization of fatty acids.
Several studies indicate choline supplementation is useful for physical endurance. In trained athletes,
plasma choline concentrations can decrease by as much as 40 percent during training or competition.
Reductions in blood choline may lead to a decline in the synthesis of acetylcholine. Choline deficiency can
result in liver and muscle damage.
Purity and Concentrations of Choline Bitartrate
Purebulk's choline bitartrate powder contains no fillers, additives or anti-caking agents. The molecule,
choline bitartrate, provides 40% choline by weight.
How should I store it?
Store in a cool, dry area protected from light. Reseal after each use.
Potential Side Effects of Choline Bitartrate
Typical side effects of ingested choline include an increase in body temperature and sweating. Nausea and
loss of appetite may result from very high serving sizes. Those with poor liver function should discuss
choline supplementation with a physician.
Bioavailability, Mixing and Solubility of Choline Bitartrate
This choline supplement is pharmaceutical-grade choline bound to tartaric acid, making it easier to absorb.
The powder is soluble in water and slightly soluble in alcohol.
References & Further Research
Linus Pauling Institute,
Micronutrient Information Center: Choline
The information at Purebulk.com is NOT a substitute for medical advice.
ALWAYS consult your doctor or pharmacist. Do not use any dietary supplement as a
replacement for conventional care, or as a reason to postpone seeing a doctor about a medical problem. Tell
all your health care providers about any complementary and alternative practices you use. Give them a full
picture of what you do to manage your health. This will help ensure coordinated and safe care.
The U.S. Food and Drug Administration (FDA) regulates herbal and other dietary supplements differently than
conventional medicines. The standards for supplements are found in the Dietary Supplement Health and
Education Act (DSHEA), a federal law that defines dietary supplements and sets product-labeling standards
and health claim limits.
Tested by Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity
and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.