REPRESENTATIVE DOCUMENTS
COA
*(Documents above may vary from batch received. Click here to request batch-specific documents)
| Amount Per Serving | % Daily Value* |
|---|---|
| Vitamin B12 (Cyanocobalamin) 2000 mcg | 83333% |
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡
These supplement facts may vary from the product you receive. Please call for exact numbers.
Other Ingredients: Mannitol
Free of: Soy, Dairy, Yeast, & Gluten.
Directions: As a dietary supplement, take 200 mg (1/16 tsp) once daily, or as directed by physician. Accurate gram weight scale recommended.
Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Potentially toxic in higher amounts. Use extreme care when measuring. Keep out of reach of children.
Cyanocobalamin is one of several forms of cobalamin that fall under the blanket term Vitamin B12. The cobalamin vitamers exert similar effects, but cyanocobalamin is the most stable when exposed to air and the easiest to purify. As indicated by the name, cyanocobalamin contains cobalt. It converts easily into adenosylcobalamin or methylcobalamin upon ingestion—the active forms of vitamin B12.
The body cannot synthesize vitamin B12, but, as an essential vitamin, it’s necessary to sustain life. The body relies on dietary sources of B12 to meet its nutritional needs. Vitamin B12 is the most chemically complex of all vitamins, and it serves numerous biological functions. Some examples include synthesizing DNA, metabolizing fatty acids and amino acids, synthesizing myelin to protect nerves, producing red blood cells, and more. Like all B vitamins, it plays a role in producing energy from food.
Mannitol is a sugar alcohol that doesn’t contribute to tooth decay, raise blood sugar, or contain many calories like regular sugar. It also has anti-caking properties, making it a good option for triturating highly concentrated vitamins. Blending mannitol and cyanocobalamin helps dilute the potency of vitamin B12 for easier supplementation.
Most individuals obtain vitamin B12 through consuming animal products like eggs, red meat, poultry, fish, and eggs. Certain groups are more susceptible to developing a vitamin B12 deficiency. For example, 20% of adults over the age of 60 have low B12. Medical conditions and lifestyle factors also contribute to B12 deficiencies. These include malabsorptive conditions that impair the body’s ability to absorb vitamin B12, such as pernicious anemia, celiac disease, and gastric bypass surgery. Vegans and (to a lesser extent) vegetarians are also at increased risk of developing B12 deficiencies, as most B12 food sources come from animal products. Taking proton pump inhibitors or metformin can also impair B12 absorption.
Prolonged vitamin B12 deficiency can damage the nervous system and the brain. Even slightly insufficient levels can result in numerous side effects, including tiredness, weakness, faintness, dizziness, balance problems, headaches, breathlessness, mood problems, confusion, memory problems, and paresthesia (e.g., pins and needles sensations).
Vitamin B12 deficiencies can also cause oral health problems, including canker sores, ulcers, and glossitis (shiny, red, and painful tongue). Individuals with B12 deficiency may become pale and notice a yellowing of the skin and eyes. Fatigue is also common.
Cyanocobalamin ensures the body has an adequate supply of vitamin B12. It’s critical for red blood cell (RBC) formation, and deficiencies can result in bloated, misshapen RBCs. Malformed RBCs have a harder time moving through the bloodstream to deliver oxygen throughout the body.
Vitamin B12 is also a cofactor for enzymes the body needs to synthesize methionine and succinyl-CoA. Methionine is essential for reducing homocysteine levels and methylation reactions, while succinyl-CoA is an important part of the citric acid cycle for energy. Myelin sheath synthesis relies on methylation reactions to protect and insulate nerves.
Vitamin B12 may support several other areas of health. These include DNA preservation, bone health, mood balance, heart health, and ocular health.
Vitamin B12 is water-soluble, and the body only absorbs a certain amount of it before excreting the excess. As a result, it has remarkably low toxicity. Large B12 doses may cause headaches, nausea, diarrhea, weakness, or tingling sensations.
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.