Supplement Facts & Directions
Supplement Facts
Serving Size: 200 milligramsServings Per Container: Varies
| Amount Per Serving | % Daily Value* |
|---|---|
| Diindolylmethane (DIM) 200 mg | † |
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡ These supplement facts may vary from the product you receive. Please call for exact numbers.
Other Ingredients: None
Free of: Added Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives.
Directions: As a dietary supplement, take 200 mg (1/16 tsp) up to twice daily or as directed by a physician. An accurate gram weight scale is recommended. For best results, refrigerate upon arrival.
Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children.
Product Details
What is DIM?
Vegetables in the Cruciferae family, also known as the Brassicaceae family, owe much of their status as healthy foods to diindolylmethane (DIM). Cruciferous vegetables like broccoli, cabbage, and cauliflower contain high amounts of indole-3-carbinol. The body breaks down this compound during digestion to produce 3,3′-Diindolylmethane.
As the name suggests, diindolylmethane is made up of two indole groups and a methane group. It is a potent antioxidant and anti-inflammatory, and it may alleviate several hormone-related health concerns by influencing estrogen metabolism. Many individuals choose to take DIM supplements, as cooking, boiling, and microwaving cruciferous vegetables reduces the bioavailability of DIM and its precursors. It also requires several servings of cruciferous vegetables per day to achieve meaningful DIM benefits.
Potential DIM Supplement Benefits
Antioxidant and Anti-Inflammatory DIM Benefits
Inflammation is an important part of the body’s natural healing process and immune response. The immune system produces free radicals to fight off germs, bacteria, and other invading threats. However, when free radicals overwhelm antioxidant levels, they cause oxidative stress, cellular damage, and inflammation. Too much inflammation or long-lasting inflammation can lead to several health problems and disorders. DIM helps combat inflammation by reducing pro-inflammatory cytokines and endoplasmic reticulum (ER) stress.
DIM also acts as an antioxidant. DIM can boost the activity of enzymes that repair and protect damaged DNA without aiding the survival of harmful cells. DIM may help prevent and protect against the proliferation of harmful, hormone-driven cellular changes by balancing estrogen levels. DIM also synergizes with Phenethyl Isothiocyanate, another cruciferous vegetable compound, to activate antioxidant enzymes.
DIM Supplement for Women
Women may benefit from taking DIM supplements in several ways. DIM may help relieve PMS symptoms caused by fluctuating estrogen. Similarly, it may help reduce the occurrence of hormonal acne. For menopausal women, DIM supplements may reduce hot flashes caused by hormonal shifts.
DIM for Men
Excess estrogen can have several adverse effects on men’s health, such as erectile dysfunction, fertility issues, and growth of breast tissue. DIM may help alleviate these effects by regulating estrogen levels. DIM also supports prostate health and slows the growth of prostate cells. It also exerts antiproliferation and antiandrogenic effects within the prostate, meaning it slows and blocks hormones that worsen unhealthy prostate cells.
DIM Supplements for Weight Loss
DIM supplements may help boost weight loss by balancing estrogen levels, as too much or too little estrogen can cause weight gain in both men and women. DIM supplements may promote the breakdown of fat cells while inhibiting the formation of new fat cells.
Potential DIM Side Effects
Based on current human research, DIM is generally safe for most individuals without causing significant side effects. Some individuals may experience headaches, gas, more frequent bowel movements, and darker urine. Individuals with hormone-sensitive health conditions or taking hormone therapies shouldn’t take DIM supplements without the supervision of a doctor. All individuals should consult with a physician before taking new supplements.
References
- https://pubmed.ncbi.nlm.nih.gov/16651444
- https://pubmed.ncbi.nlm.nih.gov/20653562/
- https://www.ncbi.nlm.nih.gov/pubmed/11352861
- https://www.ncbi.nlm.nih.gov/pubmed/11525594
- https://www.ncbi.nlm.nih.gov/pubmed/14744743
- https://www.ncbi.nlm.nih.gov/pubmed/15563214
- https://www.ncbi.nlm.nih.gov/pubmed/17002432
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059820/
- https://www.frontiersin.org/articles/10.3389/fimmu.2019.01620/full
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249911/
- https://pubmed.ncbi.nlm.nih.gov/25332705/
- https://pubmed.ncbi.nlm.nih.gov/19334074/
- https://www.ncbi.nlm.nih.gov/pubmed/24127581
- https://www.ncbi.nlm.nih.gov/pubmed/21656528
- https://pubmed.ncbi.nlm.nih.gov/25048790/
- https://pubmed.ncbi.nlm.nih.gov/15623462/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548199/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015761/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408989/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459071/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612529/
- https://www.ncbi.nlm.nih.gov/books/NBK279105/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/
- https://pubmed.ncbi.nlm.nih.gov/12665522/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889220/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689796/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835337/
- https://pubmed.ncbi.nlm.nih.gov/28586165/
Tested by Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.