| Amount Per Serving | % Daily Value* |
|---|---|
| Fucoidan Extract (Laminaria japonica) (algae) 500 mg (standardized to ≥75% total polysaccharides) |
† |
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡ These supplement facts may vary from the product you receive. Please call for exact numbers.
Other Ingredients: ≤10% Maltodextrin
Free of: Added Sugar, Soy, Dairy, Yeast and Gluten.
Directions: As a dietary supplement, take 500 mg (3/32 tsp) daily with water or as directed by a physician. An accurate gram weight scale is recommended.
Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children.
Fucoidan is a sulfated polysaccharide found in various brown seaweed species like kelp. Fucoidan’s therapeutic uses date back to ancient Chilean, Greek, and Roman civilizations, who consumed fucoidan-containing seaweeds for their health benefits. However, scientists didn’t isolate fucoidan itself until the 19th century. In the 20th century, researchers began examining its unique structure and biological effects. Today, scientists study fucoidan for its potential to support immune health, reduce inflammation, and improve cellular functions. Fucoidan supplements derived from kelp extract offer a concentrated source of this powerful polysaccharide.
Antioxidant Properties Fucoidan possesses notable antioxidant properties. It scavenges unstable free radical molecules that can cause oxidative damage to cells and tissues. Neutralizing these free radicals helps prevent cellular damage and maintains cellular integrity. Fucoidan also reduces oxidative stress by modulating other antioxidant enzymes’ activity. For example, it helps eliminate reactive oxygen species (ROS) from the body by enhancing superoxide dismutase (SOD), catalase, and glutathione peroxidase expression and activity. Fucoidan’s antioxidant mechanisms help reduce the risk of chronic conditions, support healthy aging, and protect vital cellular functions. Additionally, its ability to inhibit lipid peroxidation and chelate metal ions minimizes oxidative damage to cell membranes, promoting cellular integrity and function.
Immune System Support Fucoidan may enhance immune system function by modulating immune cell activity, such as macrophages, natural killer (NK) cells, and dendritic cells. Activating these cells helps the body identify and eliminate pathogens more effectively. Fucoidan also influences cytokine production. Cytokines are signaling molecules that mediate and regulate immunity and inflammation. Fucoidan helps maintain a healthy immune response by balancing pro-inflammatory and anti-inflammatory cytokines. Additionally, fucoidan possesses antiviral and antimicrobial properties that inhibit certain viruses and bacteria from replicating.
Anti-Inflammatory Effects Research shows that fucoidan has anti-inflammatory properties. In addition to downregulating pro-inflammatory cytokine production, fucoidan also inhibits inflammation signaling pathways, including the NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) pathway. Additionally, fucoidan promotes tissue repair and regeneration, which can be beneficial in inflammatory conditions. Fucoidan may help to resolve inflammation more quickly by facilitating the healing process.
Cellular Health and Longevity Fucoidan promotes cellular health and longevity through several mechanisms. It supports autophagy, a natural cellular process that breaks down and removes damaged or dysfunctional components. Healthy cell function depends on this cellular cleanup, as it prevents harmful proteins and organelles from building up and promoting aging and disease. Fucoidan can also induce programmed cell death (apoptosis) in abnormal or damaged cells while protecting healthy cells from stress-related damage. Its protective effects help cells survive longer while maintaining their normal functions.
Gut Health and Prebiotic Support Fucoidan has numerous beneficial properties for gut health. It acts as a prebiotic, nourishing beneficial gut bacteria (probiotics). Promoting probiotic growth and activity helps maintain a balanced gut microbiome. Fucoidan also strengthens the gut's mucosal barrier, enhancing its integrity and preventing harmful pathogens and toxins from entering the bloodstream. Additionally, fucoidan supports digestion by improving nutrient absorption.
Cardiovascular Health Research shows that fucoidan has heart-protective properties. It promotes healthier cholesterol levels by inhibiting cholesterol absorption in the intestines and promoting its excretion. Fucoidan also supports heart health by improving endothelial function. The endothelium, the thin layer of cells lining blood vessels, is crucial for regulating blood flow and vascular health. Fucoidan enhances endothelial function by acting as an antioxidant, reducing inflammation, promoting angiogenesis (new blood vessel formation), and restoring glycocalyx, a gel-like layer that covers endothelial cells. Additionally, fucoidan helps relax blood vessels and reduce pressure by promoting nitric oxide production.
Most individuals can take fucoidan without experiencing adverse effects. However, some people may experience mild digestive discomfort when consuming high amounts, such as bloating or diarrhea. Individuals with iodine sensitivity should consult their healthcare provider before taking fucoidan supplements, as kelp is a rich iodine source. Additionally, those taking blood-thinning medications should discuss fucoidan supplements with their doctor before adding them to their supplement regimen, as fucoidan may have mild anticoagulant effects.
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity, and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.