PureBulk, Inc.
Maitake Mushroom Extract (50% Polysaccharides)
Pickup available at PureBulk, Inc. during business hours. (7:00am-3:00pm M-F)
Usually ready in 24 hours
Supplement Facts
Serving Size: 500 mgServings Per Container: Varies
| Amount Per Serving | % Daily Value |
|---|---|
| Maitake Mushroom (Grifola Frondosa)(Fruiting Body) 500 mg (Standardized to ≥50% polysaccharides) |
† |
† Daily Value Not Established
‡These supplement facts may vary from the product you receive. Please call for exact numbers.
Other Ingredients: Maltodextrin
Free of: Added Sugar, Dairy, Soy, Wheat, and Yeast.
Directions: As a dietary supplement, take 500 mg 1-2 times daily or as directed by a healthcare professional. Use an accurate milligram scale for measurement.
Warning: If you are pregnant or nursing, taking medications, or have a
medical condition, consult a healthcare professional before use.
May affect blood sugar and blood pressure.
Use caution if taking medications for diabetes or hypertension.
Consult your healthcare professional if
taking blood-thinning medications.
Discontinue use at least 2 weeks prior to surgery.
Keep out of reach
of children.
Tested By Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Product Details
What is Maitake Mushroom Extract?
Maitake mushroom (Grifola frondosa), sometimes called "hen of the woods" or the "dancing mushroom," is a large, cluster-forming fungus that grows at the base of oak and other hardwood trees across Asia, Europe, and eastern North America. It has a long history of culinary and traditional use and has become one of the most studied functional mushrooms in nutrition science over the past several decades, largely because of its rich concentration of bioactive polysaccharides.
The compounds of greatest interest are beta-glucans, complex sugar molecules found in the mushroom's cell walls, along with specialized polysaccharide fractions researchers refer to as the D-fraction and SX-fraction. Researchers believe these compounds interact with immune cell receptors and metabolic pathways in ways that regular dietary mushrooms, consumed in typical culinary amounts, cannot reliably deliver.
PureBulk standardizes this maitake mushroom extract to contain 50% polysaccharide content, meaning the raw mushroom material is concentrated so that finished product contains a consistent, measurable level of these active compounds in every batch. Standardization matters because raw maitake, like most mushrooms, can vary significantly in potency depending on growing conditions. A standardized extract gives consumers a reliable, repeatable serving of the compounds the research is actually built around.
Potential Maitake Mushroom Benefits
Potent Mushroom Extract Synergy
Research backs up what many formulators have long suspected: maitake works even better in combination with other mushroom extracts.
One study found that pairing maitake with shiitake boosted immune activity more than either mushroom on its own. Another study combined maitake with shiitake and reishi and found the trio outperformed any single extract alone.
Supports Healthy Immune Cell Activity
Maitake's beta-glucans, particularly the D-fraction, are among the most extensively researched immune-supporting compounds in the mushroom kingdom. Laboratory and clinical research indicate that these polysaccharides interact with pattern-recognition receptors on immune cells, including macrophages, natural killer (NK) cells, and T-cells, which may help support the body's normal surveillance and response activity. Notably, researchers have found that maitake's D-fraction retains meaningful activity when taken orally, which distinguishes it from many polysaccharide compounds that break down before they can exert an effect.
Supports Balanced Cytokine Signaling
Beyond activating individual immune cells, researchers have studied maitake extracts for their influence on cytokine production, the chemical messengers that immune cells use to coordinate a response. Research suggests maitake polysaccharides may help support a more balanced, appropriately regulated immune signaling environment rather than simply "revving up" immune activity across the board.
Supports Healthy Blood Sugar Balance
One of the more distinctive areas of maitake research involves glucose metabolism. Several animal studies have identified specific polysaccharide fractions, most notably the water-soluble SX-fraction, that appear to support insulin sensitivity and help maintain circulating glucose levels already within a normal range. Researchers believe these effects may work through multiple mechanisms, including support for peripheral insulin sensitivity and moderation of carbohydrate absorption. While much of this research focuses on animal models to date, human data is still developing and remains a promising but early area of study.
Provides Antioxidant Support
Maitake mushrooms are a rich source of natural antioxidants, including polyphenols, ergothioneine, and other bioactive compounds that help protect cells from oxidative stress caused by free radicals. By helping to neutralize these unstable molecules, maitake may support healthy aging, promote overall cellular health, and contribute to the body's natural defense systems. Emerging research also indicates that the mushroom's antioxidant properties may work alongside its immune-supporting compounds to help maintain a healthy inflammatory response and support long-term wellness.
Potential Maitake Mushroom Side Effects
Most people generally tolerate maitake mushroom extract well. Reported side effects are uncommon and typically mild, and may include:
- Mild digestive upset, such as nausea or stomach discomfort
- Loose stools in sensitive individuals
- Rare allergic reactions in those with mushroom sensitivities
Because maitake may help support healthy blood sugar levels and may have mild blood-thinning effects, individuals taking diabetes medications or anticoagulants should consult a healthcare provider before use to help avoid potenti
Sources
- https://scispace.com/pdf/maitake-d-fraction-healing-and-preventive-potential-for-rojgzdl7c7.pdf
- https://pubmed.ncbi.nlm.nih.gov/14977447
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3751581
- https://pubmed.ncbi.nlm.nih.gov/25351719
- https://pubmed.ncbi.nlm.nih.gov/11874441
- https://pubmed.ncbi.nlm.nih.gov/22873755
- https://pubmed.ncbi.nlm.nih.gov/11207456
- https://pubmed.ncbi.nlm.nih.gov/14975363
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3268513
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7824844
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11068609
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4202470
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6837746
*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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