PureBulk, Inc.

NAD+ (Nicotinamide Adenine Dinucleotide)

$33.25
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Container: Bags
Size: 25 grams
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Supplement Facts

Serving Size: 500 milligrams
Servings Per Container: Varies
Amount Per Serving % Daily Value*
NAD
(Nicotinamide Adenine Dinucleotide)     500 mg		 †

* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value Not Established
‡ These supplement facts may vary from the product you receive. Please call for exact numbers.

Other Ingredients: None

Contains:

Free of: Added Sugar, Soy, Dairy, Yeast, Gluten, Corn & Additives.

Directions: As a dietary supplement, take 500mg (1/8 tsp) once daily, or as directed by a physician.

Warning: If you are pregnant, nursing, taking any medications or have any medical condition consult your physician before use. Keep out of reach of children.

Tested By Accredited 3rd Party Labs

PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found  here.

*NOTE: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

  • Supports cellular energy and ATP production
  • Promotes circulation and heart health
  • Enhances memory, focus, and brain function
  • Helps slow the signs of aging
  • Aids in DNA repair and provides cellular protection
  • Calms inflammation and oxidative stress
  • Supports metabolism and nutrient utilization
  • Promotes healthy, youthful-looking skin

What is Nicotinamide Adenine Dinucleotide (NAD+)?

NAD vs NMN

Nicotinamide mononucleotide (NMN) is a direct precursor to NAD+. Supplementing with NMN increases NAD+ indirectly by first undergoing enzymatic conversion, while NAD+ supplementation provides the active coenzyme itself. Both approaches aim to restore declining NAD+ levels.

Nicotinamide adenine dinucleotide (NAD+) is a naturally occurring coenzyme present in all living cells. It is critical for energy metabolism, as it helps convert nutrients into adenosine triphosphate (ATP), the primary energy molecule used by cells. Beyond energy production, NAD+ serves as a signaling molecule, playing a crucial role in DNA repair, gene expression, and cellular stress responses.

NAD+ levels decline with age, which may contribute to fatigue, reduced mitochondrial function, and other issues associated with aging. Researchers are investigating how NAD+ can help reverse this decline, supporting longevity, metabolic health, and resilience against cellular stress.

Potential Benefits of NAD+

Supports Cellular Energy Production
NAD+ is indispensable for producing ATP, the molecule every cell relies on for energy. By fueling the enzymes in the mitochondrial electron transport chain, NAD+ helps convert carbohydrates, fats, and proteins into usable energy. Adequate NAD+ levels can reduce fatigue, enhance stamina, and ensure that tissues with high energy demands, such as the brain, muscles, and heart, function optimally.

Improves Cardiovascular Health
The heart is one of the body’s most energy-demanding organs. NAD+ supports healthy cardiovascular function by fueling energy production in heart muscle cells and maintaining vascular integrity. Research shows that NAD+ plays a crucial role in regulating blood vessel dilation, enhancing circulation, and promoting resilience against oxidative stress—all essential factors for maintaining long-term heart health.

Boosts Cognitive Function
Like the heart, the brain consumes a significant amount of energy. NAD+ supports optimal brain function by maintaining the health of neurons’ mitochondria and ensuring the nervous system has an efficient energy supply. Adequate NAD+ levels may help protect against cognitive decline, improve memory retention, and enhance focus by supporting neurotransmitter balance and reducing oxidative damage in the brain.

NAD+ & Resveratrol

Resveratrol, a polyphenol found in grapes and berries, is often paired with NAD+ supplementation. While NAD+ fuels sirtuin enzymes, resveratrol is thought to activate them. Together, they work synergistically to support longevity pathways, mitochondrial health, and cellular resilience.

Provides Anti-Aging Effects
NAD+ is closely tied to longevity pathways, as it is critical for activating sirtuins—proteins associated with healthy aging. By maintaining mitochondrial efficiency and reducing cellular stress, NAD+ supplementation may help combat fatigue, improve vitality, and slow age-related functional decline.

Promotes DNA Repair
NAD+ is essential for activating PARP enzymes, which are crucial for repairing damaged DNA. Maintaining adequate NAD+ levels supports genomic stability, which is critical for healthy aging, cellular resilience, and protection against genetic errors accumulating over time.

Reduces Inflammation
Chronic inflammation accelerates the aging process and contributes to numerous chronic health issues. NAD+ influences inflammatory signaling pathways and helps regulate immune system activity. By reducing oxidative stress and balancing inflammatory responses, NAD+ may help calm chronic inflammation, support joint comfort, and boost overall systemic wellness.

Enhances Metabolic Function
NAD+ drives enzymes involved in glucose and fatty acid metabolism, ensuring that nutrients convert efficiently into usable energy. Adequate NAD+ improves insulin sensitivity, energy balance, and mitochondrial function, making it particularly relevant for weight management and metabolic health.

NAD+ Skincare Benefits
Skin health relies on rapid cell turnover and repair—both of which require NAD+. By supporting DNA repair and reducing oxidative damage, NAD+ may help improve skin elasticity, reduce the appearance of fine lines, and protect against environmental stressors such as UV radiation.

Potential Side Effects of NAD+

Most individuals can take NAD+ supplements without experiencing significant adverse effects. Some may experience mild side effects, including mild digestive discomfort (such as nausea or cramping), headache or dizziness in sensitive individuals, or temporary flushing or warmth. Individuals with preexisting health conditions or those taking medication should consult a physician before starting any new health supplement.

References and Research

How to Use

Solubility: Water-soluble.

What to take with: Individuals can take NAD+ supplements with water. Combining NAD+  and resveratrol may provide synergistic benefits.

When to take: Individuals should take NAD+ supplements in the morning to align with natural NAD+ circadian rhythms.

Recipe

  • NAD+ & Resveratrol Longevity Elixir: Add 300mg of NAD+ supplement powder and 500mg of resveratrol supplement powder to 8 oz of warm (not boiling) green tea. Stir until fully dissolved. Optional: add a teaspoon of honey or stevia for a sweeter flavor.

 Spoon Set or Scale Needed?

Individuals can use measuring spoons for approximate servings, but a milligram scale offers the best precision when measuring supplement serving sizes.