What Does Hyaluronic Acid Do?
Hyaluronic acid, also known as hyaluronan and abbreviated to HA, is a significant component of connective
tissues, joint and tendon tissues, and the synovial fluid that reduces friction between the joints. It binds
cells together to improve cartilage’s resilience against compression and helps lubricate the joints. It also
helps connected tissues slide between neighboring muscles.
Hyaluronic acid’s role in skin appearance is one of its better-known functions. It plays a role in the body’s
inflammation response to help regenerate skin tissues and repair wounds. It can bind up to 1000 times its
weight in water, which is why it gives the skin a supple and hydrated appearance. Naturally occurring
hyaluronic acid levels decrease in the skin with age, which contributes to sagging and wrinkles. Hyaluronic
acid is water-soluble and forms a gel-like substance when combined with water.
Hyaluronic Acid for Joints
Hyaluronic acid supports joint health in several ways. It makes up a significant portion of the synovial
fluid that lubricates joints to reduce friction. Hyaluronic acid also helps joints resist compression by
coating cartilage in a protective layer. It also lubricates connective tissues to allow the tissues and
muscles to slide over each other more easily. It also synergizes without joint health supplements, including
glucosamine and chondroitin.
Potential Hyaluronic Acid Benefits for Skin
Hyaluronic Acid and Wound Healing
Hyaluronic acid levels increase following skin damage to expedite the wound healing process. It helps
regulate the body’s inflammatory response and promotes red blood cell production around the injured area. It
has analgesic and antibacterial properties, which help reduce pain and the risk of infection. It can also
reduce the size of wounds for faster recovery.
Hyaluronic Acid for Skin + Acne
Hyaluronic acid is a significant component of skin. Research shows that oral hyaluronic acid solutions help
improve the appearance of skin. One study noted that participants taking an oral HA solution saw significant
improvements in skin elasticity and hydration. The participants also experienced a notable reduction in skin
roughness and the appearance of wrinkles. HA may help improve the appearance of acne, too. Hyaluronic acid
helps support the body’s skin barrier, which may reduce the irritation and redness caused by acne.
Vegan and Wheat-Free Hyaluronic Acid Supplement
PureBulk’s Hyaluronic Acid supplement is certified vegan. It is produced through wheat-free fermentation and
is free of any animal byproducts.
How to Make Hyaluronic 1% Solution
Only dissolved hyaluronic acid powder in cold water when preparing this Hyaluronic Acid 1% solution. Never
attempt to dissolve Hyaluronic Acid in hot or room temperature water.
- 3.56 grams Hyaluronic Acid Powder.
- 12 fluid ounces cold distilled water.
- 16 fluid ounce or larger capacity wide mouth glass or plastic water bottle with a tightly sealing lid.
- Gram weight measuring scale with an accuracy of 0.01 gram and a capacity of 100 grams.
- Pint sized glass or plastic measuring cup.
- A wide-range cooking thermometer (that can go down to freezing)
For best results, use a digital
milligram scale to weigh the hyaluronic acid supplement.
- Measure out 12 fluid ounces distilled water and pour into water bottle.
- Place in refrigerator for about 4 hours.
- Measure the temperature of water to confirm water temperature is 39°F (4°C) or less.
- Measure 3.56 grams Hyaluronic Acid powder (approximately two level teaspoons).
- Add the Hyaluronic Acid powder into the water bottle on top of the cold water.
- Seal the bottle lid tightly and shake the bottle a few times. The Hyaluronic Acid powder will not appear
to dissolve but will clump together in floating white masses. This is normal.
- Place the water bottle with the Hyaluronic Acid powder and cold water into the refrigerator (but do not
- Periodically, about every two to four hours, shake the bottle and then place immediately back into
The hyaluronic acid clumps will turn clear and begin to dissolve after 4-8 hours. It takes approximately
12-24 hours for all the clumps to dissolve and the water to thicken into a 1% hyaluronic acid serum. The
solution has a viscosity between maple syrup and honey but is still pourable.
For internal use: One ounce equals approximately 150 milligrams of Hyaluronic Acid.
How to Store Hyaluronic Acid Solution
Store the hyaluronic acid solution in the refrigerator to preserve the quality and maximize its shelf-life.
Hyaluronic acid solution lasts a minimum of 48 to 72 hours in the refrigerator. However, it can last longer
so long as the HA solution remains sterile. Microbial contamination causes spoilage and reduces the
solution’s thickness. If the solution becomes thin or loses its thickness, discard it. Changes in viscosity
indicate spoilage. Do not attempt to store your HA solution at room temperature without the addition of
Hyaluronic Acid and Vitamin C
Hyaluronic acid and vitamin C
complement each other’s skin-enhancing properties. They work together to lock in moisture, protect the
skin, and improve signs of aging skin.
Adding Preservatives to the Hyaluronic Acid Solution
Adding preservatives like ascorbic acid
(vitamin C) or DMAE
bitartrate can prolong the HA solution’s shelf-life in the refrigerator and reduce the likelihood of
microbial contamination. Choosing a storage container with a dropper or a pump to dispense the serum also
helps prevent contamination.
Add and dissolve approximately 6 grams Ascorbic Acid and 3 grams DMAE Bitartrate to 12 fluid ounces of
distilled water at room temperature. After both powders dissolve completely, chill the 12 fluid ounces to
39°F (4°C) (check with a wide-range cooking thermometer), then follow the recipe directions above.
When taken orally, this preserved HA solution will net the following nutritional supplements per level
- Hyaluronic Acid: 150mg
- Ascorbic Acid: 250mg
- DMAE Bitartrate: 125mg
This hyaluronic acid solution can last 1-3 months with the addition of vitamin C. If the mixture starts to
turn yellow, it means the vitamin C has oxidized. Once this happens, the solution is less effective and
prone to contamination. Discard any yellowing solution and make a new batch. If this recipe yields too much
product to use before the solution oxidizes, adjust the recipe as needed to make the preferred amount of
Tested by Accredited 3rd Party Labs
PureBulk's supplements are tested by accredited third party labs in the USA to ensure their identity, purity,
and potency. To receive a copy of these test results or any other PureBulk supplement please fill out the COA request form found here.