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Toxin elimination is part of the body's natural defense mechanisms to maintain health and homeostasis. Toxins are harmful substances that can disrupt normal cellular function, damage tissues, and lead to various health problems if they accumulate in the body. Our bodies are constantly exposed to various toxins in our environment, food, and even within our bodies due to metabolic processes. Some common toxins encountered in day-to-day life include air pollutants, heavy metals, pesticides, alcohol, cigarette smoke, and food preservatives.
The liver is the primary detoxification organ. It metabolizes and neutralizes toxins, drugs, and metabolic waste products, making them easier to excrete. Detox supplements support the body's natural detoxification processes to reduce the burdens of toxin overload within the body. They work by providing essential nutrients and antioxidants that optimize liver function, promote toxin elimination, enhance antioxidant defenses, and support cellular detoxification pathways. PureBulk carries numerous detox support supplements that fall into three categories: antioxidant detoxification, liver function, and heavy metal binding.
Alpha Lipoic Acid (ALA): ALA is a potent antioxidant that safeguards liver cells from damage by neutralizing free radicals and toxins. Moreover, ALA supports liver health by facilitating the regeneration of glutathione, a crucial antioxidant for detoxification processes within the liver. PureBulk carries Alpha Lipoic Acid (R-ALA) and Alpha Lipoic Acid (RS-ALA). [1 - 4]
Ascorbic Acid (Vitamin C). Vitamin C is another free radical- and toxin-neutralizing antioxidant. It supports detoxification processes by reducing oxidative stress and bolstering the immune system. A well-functioning immune system enhances the body's ability to eliminate harmful substances. PureBulk carries Ascorbic Acid (Vitamin C) Powder, Ascorbyl Palmitate (Vitamin C Ester) Powder, Calcium Ascorbate (Vitamin C) Powder, and Acerola Cherry Vitamin C Extract 25%. [4, 5 - 7]
Glutathione: Glutathione is a powerful antioxidant and a pivotal player in the body's detoxification processes. It supports the liver's detoxification pathways by binding to and neutralizing toxins, heavy metals, and free radicals, helping to eliminate them from the body. [8 - 11]
Grape Seed Extract Powder: Grape seed extract contains antioxidants known as proanthocyanidins. These antioxidants scavenge free radicals and reduce oxidative stress in the body, particularly in the liver. Grape seed extract helps protect liver cells from damage by neutralizing harmful free radicals and supports their optimal function by eliminating toxins and metabolic waste products. [12 - 14]
Grapefruit Seed Extract Powder: Grapefruit seed extract supports detoxification through its potent antioxidant and antimicrobial properties. It supports the liver's ability to neutralize toxins and metabolic by-products by scavenging free radicals and reducing oxidative damage. Its antimicrobial properties promote gut health by helping eliminate harmful bacteria, viruses, and parasites from the digestive tract. Gut health is essential for detoxification because the gastrointestinal tract facilitates toxin elimination. [15 - 17]
Green Tea Extract Powder: Green tea extract contains high levels of antioxidants, including epigallocatechin gallate (EGCG) and polyphenols. EGCG supports detoxification by enhancing liver function and aiding in toxin excretion. Polyphenols reduce oxidative stress and inflammation in the body. Reducing oxidative stress and inflammation in the body is crucial for detoxification because these processes can impair normal cell and organ functions, including those involved in detoxification. PureBulk carries Green Tea Extract Powder (50% EGCG) and Green Tea Extract Powder (50% Polyphenols). [18 - 24]
N-Acetyl L-Cysteine (NAC): As a precursor to glutathione, NAC supports toxin neutralization and elimination. NAC also protects liver cells against oxidative stress and damage. [25 - 28]
Quercetin: Quercetin is a plant flavonoid known for its antioxidant and anti-inflammatory properties. It supports detoxification by scavenging free radicals and reducing inflammation in the body. Quercetin also promotes liver health by aiding in toxin elimination. [29 - 31]
Selenium: Selenium is an essential mineral and cofactor for antioxidant defense system enzymes, including glutathione peroxidase. Supporting glutathione activity enhances antioxidant defenses, reduces oxidative stress, and protects cells from damage. Additionally, selenium helps eliminate toxins by facilitating the metabolism and excretion of harmful substances. [32 - 35]
Taurine: Taurine is an amino acid with antioxidant properties. It supports the body's detoxification processes by protecting cells from oxidative stress and promoting bile salt production. Bile salts are essential for excreting toxins from the body. [36 - 39]
Zinc: Zinc is an essential mineral for many bodily functions, including immune function and antioxidant defense systems. It also helps synthesize glutathione antioxidants that support detoxification processes in the liver. Among the different forms of zinc, zinc picolinate is the best choice for detox support. Chelating zinc with picolinic acid enhances its absorption, allowing it to reach liver tissues more effectively. [40 - 43]
Beetroot (Betanin): Beetroot contains betanin, a detoxifying compound that supports liver health. It helps the liver metabolize toxins and other harmful substances to reduce their burden on the liver. [44 - 47]
Berberine: Berberine is a compound found in various plants, including goldenseal. It exerts hepatoprotective effects and reduces toxin accumulation in the body by enhancing the liver's ability to metabolize and eliminate these harmful substances. Berberine also facilitates the breakdown and removal of toxic substances from the liver by promoting detoxification pathway enzyme production. Additionally, its anti-inflammatory and antioxidant properties help protect liver cells from oxidative stress and inflammation damage. [48 - 50]
Calcium D-Glucarate: Calcium D-Glucarate is a form of glucaric acid that supports toxin and hormone detoxification in the liver, facilitating their excretion from the body. D-Glucarate enhances glucuronidation activity. Glucuronidation is a detoxification pathway in the liver that binds toxins and makes them more water-soluble for easier removal. [51 - 53]
Diindolylmethane (DIM) Powder: DIM is a compound in cruciferous vegetables like broccoli and cauliflower. It supports liver detoxification by modulating estrogen metabolism, specifically favoring the production of 2-hydroxyestrone, a less harmful form of estrogen. DIM helps to balance hormone levels and reduce the burden of toxins on the liver by promoting the metabolism of estrogen and other hormones. DIM also protects the liver against inflammation-induced damage. [54 - 56]
L-Cysteine: L-Cysteine is an amino acid and an essential building block for glutathione antioxidants. L-Cysteine also helps synthesize metallothionein, a protein that binds heavy metals and aids in their excretion. [57 - 59]
L-Glutamine: L-Glutamine is another amino acid that supports detoxification by promoting glutathione synthesis. It also helps the liver detoxify and remove ammonia. It supports liver function by protecting liver cells from oxidative stress- and toxin-induced damage. [60 - 62]
L-Methionine: L-Methionine is an essential amino acid and precursor to glutathione. It supports detoxification processes and liver function by helping synthesize essential proteins and enzymes for detoxification pathways. PureBulk carries L-Methionine and DL-Methionine. [63 - 65]
Milk Thistle Extract (80% Silymarin): Milk thistle extract contains silymarin compounds with potent hepatoprotective properties. Silymarin supports liver health by promoting hepatic cell regeneration, protecting against toxins, and supporting the liver's antioxidant defenses. Furthermore, milk thistle supports detoxification processes by stimulating bile production, which aids in toxin elimination from the liver and the body. [4, 66 - 72]
Myo-Inositol Powder (Vitamin B8): Myo-inositol is a B-vitamin-like compound that participates in cellular signaling and neurotransmitter function. These processes are crucial for liver health as they regulate metabolic pathways, influence hormone secretion, and ensure optimal liver function. [73 - 76]
TUDCA (Tauroursodeoxycholic Acid): TUDCA is a bile acid that supports liver health and detoxification processes. It enhances the liver's ability to process and excrete toxins and helps protect liver cells from damage. It can also help repair liver damage. [77 - 83]
Chlorella: Chlorella is a vegan-friendly, nutrient-dense freshwater algae that supports liver health and detoxification. Its unique properties enable it to bind to heavy metals and other toxins in the body, facilitating their removal through the digestive system. Binding to these harmful substances also helps reduce their burden on the liver and supports its detoxification functions. [84 - 87]
Spirulina: Spirulina is a blue-green algae with high nutritional content, including vitamins, minerals, antioxidants, and protein. Like chlorella, it supports detoxification processes by binding to heavy metals and toxins to help remove them from the body, particularly in the liver. It is also vegan-friendly. [88 - 90]
